Güncel Gönderiler: Makale Koleksiyonu
Toplam kayıt 85, listelenen: 21-40
-
Effects of oral zinc administration on long-term ipsilateral and contralateral testes damage after experimental testis ischaemia-reperfusion
(Wiley, 2017)The purpose of this study was to examine potential long-term post-torsion changes that can occur in the histopathology, biochemistry and spermatogenesis of both torsioned and nontorsioned opposite testes. The study also ... -
Somatic SNPs of the BRCA2 gene at the fragments encoding RAD51 binding sites of canine mammary tumors
(Wiley, 2017)Mammary tumors are the most common tumor type both in women and in female dogs. In women, heritable breast cancers have been linked mutations in the breast cancer susceptibility gene BRCA2 and it contains eight BRC repeats ... -
Nephroprotective potential of carnitine against glycerol and contrast-induced kidney injury in rats through modulation of oxidative stress, proinflammatory cytokines, and apoptosis
(British Inst Radiology, 2016)Objective: Contrast media (CM) are a major cause of nephropathy in high-risk patients. The aim of this study was to examine the effects of carnitine (CAR) in advanced nephrotoxicity due to CM administration in rats with ... -
Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa
(Taylor & Francis Ltd, 2016)Context Nigella sativa L. (Ranunculaceae) (NS) is traditionally used to treat many conditions such as inflammation. Objective This study evaluates the effects of NS seeds ethanol extract in paracetamol-induced acute ... -
The Effects of Argan Oil in Second-degree Burn Wound Healing in Rats
(H M P Communications, 2016)Argan oil, produced from the kernels of the argan tree (Argania spinosa), has been shown to have antioxidant properties. To examine the effect of argan oil in second-degree burn wound healing, an in vivo experiment was ... -
Role of oxidative stress in the pathophysiology of Toxoplasma gondii infection
(Sage Publications Inc, 2016)Oxidative stress (OS) plays an essential role in the pathogenesis of common neurodegenerative diseases. We have previously shown that Toxoplasma gondii (T. gondii) induces high nitric oxide (NO) production, glial activation, ... -
Increased expressions of ADAMTS-13 and apoptosis contribute to neuropathology during Toxoplasma gondii encephalitis in mice
(Wiley, 2016)Toxoplasma gondii (T. gondii) is a protozoan parasite with the potential of causing severe encephalitis among immunocompromised humans and animals. Our previous study showed that T. gondii induces high nitric oxide (NO) ... -
Effect of Platelet-Rich Fibrin on Peripheral Nerve Regeneration
(Lippincott Williams & Wilkins, 2016)Purpose:This study aimed to evaluate the effect of platelet-rich fibrin (PRF) on peripheral nerve regeneration on the sciatic nerve of rats by using functional, histopathologic, and electrophysiologic analyses.Materials ... -
Tnf-alpha inhibition by infliximab as a new target for the prevention of glycerol-contrast-induced nephropathy
(Elsevier Science Bv, 2015)Contrast medium-induced nephropathy (CIN) remains as a problem with high incidence and mortality rates. The aim of this study is to examine the roles of infliximab (INF) in the glycerol (GLY) and CIN model in rats. The ... -
Does Bosentan Protect Diabetic Brain Alterations in Rats? The Role of Endothelin-1 in the Diabetic Brain
(Wiley, 2015)Diabetes mellitus (DM) is a major problem all over the world, affecting more people in recent years. Individuals with diabetes are more prone to disease than non-diabetics, especially vascular complications. The aim of ... -
Increased Expressions of ADAMTS-13, Neuronal Nitric Oxide Synthase, and Neurofilament Correlate with Severity of Neuropathology in Border Disease Virus-Infected Small Ruminants
(Public Library Science, 2015)Border Disease (BD), caused by Pestivirus from the family Flaviviridae, leads to serious reproductive losses and brain anomalies such as hydranencephaly and cerebellar hypoplasia in aborted fetuses and neonatal lambs. In ... -
Neospora caninum: the First Demonstration of the Enteroepithelial Stages in the Intestines of a Naturally Infected Dog
(Elsevier Sci Ltd, 2015)A 1.5-month-old Kangal breed puppy from a dairy cattle farm died after showing severe diarrhoea and incoordination. Necropsy examination revealed multifocal pulmonary consolidation and necrosis and fibrinohaemorrhagic ... -
Nitric oxide production increases during Toxoplasma gondii encephalitis in mice
(Academic Press Inc Elsevier Science, 2015)Toxoplasma gondii is an intracellular parasite with the potential of causing severe encephalitis among immunocompromised human and animals. The aim of this experimental study was to investigate the immunomodulatory and ... -
What is the role of bosentan in healing of femur fractures in a rat model?
(Springer Japan Kk, 2015)The purpose of this study was to examine the effects bosentan (which is a strong vasoconstrictor) on bone fracture pathophysiology, and investigate the roles of the nonselective endothelin 1 receptor blocker bosentan on ... -
The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus
(Springer, 2015)Purpose The aim of this study is to show the effect of a new mechanism on endothelin (ET) receptors in the physiopathology of diabetes-related pulmonary injury. We tested the hypothesis that dual ET-1 receptor antagonism ... -
eNOS and iNOS trigger apoptosis in the brains of sheep and goats naturally infected with the border disease virus
(F Hernandez, 2015)In this study, apoptotic and anti-apoptotic mechanisms and if present, which pathway to trigger the apoptosis in the brains of Border Disease Virus (BDV) infected lambs (n=10) and goat kids (n=5) were investigated. Briefly, ... -
A new approach to Neospora caninum infection epidemiology: neosporosis in integrated and rural dairy farms in Turkey
(Scientific Technical Research Council Turkey-Tubitak, 2014)Both cattle and dogs were examined in modern and rural dairy farms that had a history of abortion over 5%. The blood samples were collected from 427 aborted cattle and the sera were tested using a commercial ELISA test ... -
Ginkgo Biloba Extract (EGb 761) Protects The Mice Brain Against Fluoride-Induced Oxidative Stress
(Parlar Scientific Publications (P S P), 2014)The aim of this study was to investigate the effects of Ginkgo biloba extract (EGb 761) on oxidative stress and the histopathological changes in brain tissues of mice exposed to fluoride administration. A total of 24 mice ... -
Effects of ozone therapy and taurine on ischemia/reperfusion-induced testicular injury in a rat testicular torsion model
(Tubitak Scientific & Technical Research Council Turkey, 2014)Background/aim: To investigate the effect of ozone and/or taurine treatment comparatively on testicular damage due to ischemia/reperfusion (I/R) injury in an experimental torsion model in rats. Materials and methods: Adult ... -
The Ocular Endothelin System: A Novel Target for the Treatment of Endotoxin-Induced Uveitis With Bosentan
(Assoc Research Vision Ophthalmology Inc, 2014)PURPOSE. We compared the anti-inflammatory effects of bosentan and dexamethasone in endotoxin-induced uveitis (EIU). METHODS. Endotoxin-induced uveitis was induced by subcutaneous injection of lipopolysaccharide (LPS, 200 ...
