Tıbbi Genetik Anabilim Dalı
Güncel Gönderiler
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CAG polymorphism in the androgen receptor gene in women may be associated with nodulocystic acne
(Termedia Publishing House Ltd, 2019)Introduction: Acne vulgaris (AV) is a multifactorial, inflammatory disease of the pilosebaceous unit. Hormones play a major role in the pathogenesis of acne. In cases of hyperandrogenism; hirsutism, acne, seborrhoea and ... -
Interleukin (IL)-17F (H161R) and IL-23R (R381Q) Gene Polymorphisms in Turkish Population with Periodontitis
(Amber Publication, 2015)Background: Periodontitis is triggered by periodontal pathogens and influenced by environmental and genetic factors. Genes encoding molecules related to the immune response are the main candidates for polymorphisms analysis ... -
The frequency of Familial Mediterranean fever gene mutations and genotypes at Kirikkale and comparison with the mean of regional MEFV mutation frequency of Turkey
(Springer, 2014)In this study we have retrospectively analysed the mutation spectrum of the 351 Familial Mediterranean fever patients referred to KA +/- rA +/- kkale University Faculty of Medicine, Department of Medical Genetics Laboratory ... -
MEFV gene mutations in Henoch- Schonlein purpura
(Wiley, 2013)AimCoexistence of familial Mediterranean fever (FMF) with various systemic vasculitides, including Henoch-Schonlein purpura (HSP) and other inflammatory disorders has been reported and the MEFV gene has been suggested to ... -
Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction
(Oxford Univ Press, 2010)Methods. Given the phenotype of Tshz3 mutant mice, we considered that Teashirt genes, which code for a family of transcription factors, might represent candidate genes for human PUJO. To evaluate this possibility, we used ... -
Hereditary haemochromatosis gene (HFE) H63D mutation shows an association with abnormal sperm motility
(Springer, 2009)The aim of this study was to screen infertile men for HFE H63D mutation in correlation with clinical characteristics of infertile men (sperm concentration, sperm motility, morphology, testicular volume, Follicle Stimulating ... -
The effect of the angiotensin-converting enzyme gene polymorphism on the depression and anxiety levels
(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2009)Objective: We aimed to investigate the relationship between the angiotensin-converting enzyme (ACE) gene insertion (I) and deletion (D) polymorphism and the levels of anxiety and depression. Methods: This is a cross-sectional ... -
Adhesion of beta1 integrin to fibronectin regulates CAM-DR phenotype via p21(WAF1/cip1) in HL60 acute myeloid leukemia (AML) cells
(Tubitak Scientific & Technical Research Council Turkey, 2008)Aims: Drug resistance is a major obstacle for a successful cancer therapy. Cell adhesion mediated drug resistance (CAM-DR) is a novel type of drug resistance and generated via interaction of cancer cells with the ... -
Salmonella typhimurium aroB-encoding murine IL-18 or CD40L: evaluation for gene therapy
(Blackwell Publishing, 2006)… -
HFE H63D mutation frequency shows an increase in Turkish women with breast cancer
(Bmc, 2006)Background: The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously been shown including hepatocellular and nonhepatocellular ...
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