Oxidative stress in akkaraman ewes with seropositive for schmallenberg Virus

Abstract

The aim of this study was to determine oxidant-antioxidant status by evaluating some oxidative stress parameters (nitric oxide (NO), malondialdehyde (MDA), total antioxidant status (TAS), total oxidant status (TOS), catalase activity) in clinically healthy Akkaraman ewes with seropositive for Schmallenberg virus (SBV). The study consisted of four positive, six suspected and seven negative-control blood sera in terms of specific antibody for SBV by using commercial ELISA kits. Even though there were no significant statistical differences (P>0.05), the highest NO level was in sera with SBV specific antibody positive while the lowest TOS level was in sera with SBV specific antibody negative. The values of TAS in sera were very similar in the groups (P=0.981). While the MDA levels of sera with SBV specific antibody positive and suspected were similar, the statistical difference was found between the MDA level of sera with SBV specific antibody positive and negative (P=0.021). The catalase activity of sera with SBV specific antibody positive was lower (P=0.030) than the catalase activity of sera with SBV suspected whereas the catalase activities in positive and negative groups and the catalase activities in suspected and negative groups were similar. In conclusion, it was determined that MDA level was affected in Akkaraman ewes that are SBV specific antibody positive without clinical symptoms. © 2018 Ataturk Universitesi.All Rights Reserved.