dc.contributor.author | Ulker, Hayriye Esra | |
dc.contributor.author | Ulker, Mustafa | |
dc.contributor.author | Gumus, Hasan Onder | |
dc.contributor.author | Yalcin, Muhammet | |
dc.contributor.author | Sengun, Abdulkadir | |
dc.date.accessioned | 2020-06-25T18:07:40Z | |
dc.date.available | 2020-06-25T18:07:40Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Hayriye Esra Ülker, Mustafa Ülker, Hasan Önder Gümüş, Muhammet Yalçın, Abdulkadir Şengün, "Cytotoxicity Testing of Temporary Luting Cements with Two- and Three-Dimensional Cultures of Bovine Dental Pulp-Derived Cells", BioMed Research International, vol. 2013, Article ID 910459, 6 pages, 2013. | en_US |
dc.identifier.issn | 2314-6133 | |
dc.identifier.uri | https://doi.org/10.1155/2013/910459 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/5635 | |
dc.description | SENGUN, Abdulkadir/0000-0002-6053-160X | en_US |
dc.description | WOS: 000323072000001 | en_US |
dc.description | PubMed: 23984419 | en_US |
dc.description.abstract | This study evaluated the cytotoxicity of eugenol-containing and eugenol-free temporary luting cements. For cytotoxicity testing, bovine pulp-derived cells transfected with Simian virus 40 Large T antigen were exposed to extracts of eugenol-containing (Rely X Temp E) and eugenol-free (Provicol, PreVISION CEM, and Rely X Temp NE) temporary luting cements for 24 h. The cytotoxicity of the same materials was also evaluated in a dentin barrier test device using three-dimensional cell cultures of bovine pulp-derived cells. The results of the cytotoxicity studies with two-dimensional cultures of bovine dental pulp-derived cells revealed that cell survival with the extracts of Rely X Temp E, Provicol, PreVISION CEM, and Rely X Temp NE was 89.1%, 84.9%, 92.3%, and 66.8%, respectively. Rely X Temp NE and Provicol showed cytotoxic effects on bovine dental pulp-derived cells (P < 0.05). The results of the dentin barrier test revealed that cell survival with the above-mentioned temporary cement was 101.5%, 91.9%, 93.5%, and 90.6%, respectively. None of the temporary luting cements significantly reduced cell survival compared with the negative control in the dentin barrier test (P > 0.05). Biologically active materials released from temporary luting cements may not influence the dentine-pulp complex if the residual dentine layer is at least 0.5 mm thick. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Hindawi Publishing Corporation | en_US |
dc.relation.isversionof | 10.1155/2013/910459 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | Cytotoxicity Testing of Temporary Luting Cements with Two- and Three-Dimensional Cultures of Bovine Dental Pulp-Derived Cells | en_US |
dc.type | article | en_US |
dc.contributor.department | Kırıkkale Üniversitesi | en_US |
dc.relation.journal | Biomed Research International | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |