dc.contributor.author | Vural, Altugan Cahit | |
dc.contributor.author | Odabas, Sedat | |
dc.contributor.author | Korkusuz, Petek | |
dc.contributor.author | Saglam, Atiye Seda Yar | |
dc.contributor.author | Bilgic, Elif | |
dc.contributor.author | Cavusoglu, Tarik | |
dc.contributor.author | Vargel, Ibrahim | |
dc.date.accessioned | 2020-06-25T18:23:14Z | |
dc.date.available | 2020-06-25T18:23:14Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Altugan Cahit Vural, Sedat Odabas, Petek Korkusuz, Atiye Seda Yar Sağlam,
Elif Bilgiç, Tarık Çavuşoğlu, Erhan Piskin & İbrahim Vargel (2017) Cranial bone regeneration via
BMP-2 encoding mesenchymal stem cells, Artificial Cells, Nanomedicine, and Biotechnology,
45:3, 544-550. | en_US |
dc.identifier.issn | 2169-1401 | |
dc.identifier.issn | 2169-141X | |
dc.identifier.uri | https://doi.org/10.3109/21691401.2016.1160918 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/7050 | |
dc.description | Odabas, Sedat/0000-0002-7844-7019; KORKUSUZ, PETEK/0000-0002-7553-3915 | en_US |
dc.description | WOS: 000394598300019 | en_US |
dc.description | PubMed: 27002739 | en_US |
dc.description.abstract | Cranial bone repair and regeneration via tissue engineering principles has attracted a great deal of interest from researchers during last decade. Here, within this study, 6mm critical-sized bone defect regeneration via genetically modified mesenchymal stem cells (MSC) were monitored up to 4 months. Cranial bone repair and new bone formations were evaluated by histological staining and real time PCR analysis in five different groups including autograft and bone morphogenetic protein-2 (BMP-2) transfected MSC groups. Results presented here indicate a proper cranial regeneration in autograft groups and a prospering regeneration for hBMP-2 encoding mesenchymal stem cells. | en_US |
dc.description.sponsorship | Turkish Academy of Sciences (TUBA)Turkish Academy of Sciences; Kirikkale University Scientific Research Projects Coordination UnitKirikkale University | en_US |
dc.description.sponsorship | Erhan Piskin was supported by the Turkish Academy of Sciences (TUBA) as a full member. This study is partially supported by Kirikkale University Scientific Research Projects Coordination Unit. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.relation.isversionof | 10.3109/21691401.2016.1160918 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Bone morphogenetic protein-2 | en_US |
dc.subject | cranial bone regeneration | en_US |
dc.subject | critical size defect | en_US |
dc.subject | mesenchymal stem cell | en_US |
dc.subject | transfection | en_US |
dc.title | Cranial bone regeneration via BMP-2 encoding mesenchymal stem cells | en_US |
dc.type | article | en_US |
dc.contributor.department | Kırıkkale Üniversitesi | en_US |
dc.identifier.volume | 45 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 544 | en_US |
dc.identifier.endpage | 550 | en_US |
dc.relation.journal | Artificial Cells Nanomedicine And Biotechnology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |