Browsing Temel Tıp Bilimleri Bölümü by Author "Saygun, Oral"
Now showing items 1-4 of 4
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The Effect of Hypothermia on Splanchnic Flows and Lung in a Two-Hit Hemorrhagic Shock Model
Deniz, Turgut; Agalar, Canan; Agalar, Fatih; Comu, Faruk M.; Caglayan, Osman; Alpay, Yesim; Saygun, Oral (Academic Press Inc Elsevier Science, 2010)Background. To evaluate the effect of hypothermia on bacterial translocation, splanchnic vascular flow, lung tissue weight, and levels of malondialdehyde (MDA) and nitric oxide (NO) in a two-hit model of hemorrhagic shock. ... -
The Effects of Ara-C, Simvastatin and combo therapy on İY energy metabolism of HL-60 promyolocytic leukemia cell lines
Boyunağa, Hakan; Dikmen, Z. Günnur; Kenar, Levent; Saygun, Oral; Keleş, Hatice; Ural, Ali Uğur; Lale, Mustafa (2013)Amaç: Kanser hücrelerinde metabolik yönelim, ortamın oksijen içeriği ve substrat konsantrasyonuna göre düzenlenmektedir. Kanser hücresinin enerji metabolizmasının düzenlenmesine yönelik çeşitli terapotik ajanlar halen ... -
The Effects of Simvastatin on Ischemia Reperfusion Injury in an Experimental Colon Anastomosis Model
Akarsu, Mahmut; Saygun, Oral; Aydinuraz, Kuzey; Aydin, Oktay; Daphan, Cagatay Erden; Tanrikulu, Fatma Benli; Comu, Faruk Metin (Springer India, 2017)Anastomotic leakage is more frequently reported in colonic anastomoses. Ischemia reperfusion injury is one of the main reasons for anastomotic leakage. Simvastatin is known to prevent tissue damage induced by free oxygen ... -
The value of CRP, IL-6, leptin, cortisol, and peritoneal caspase-3 monitoring in the operative strategy of secondary peritonitis
Pehlivanli, Faruk; Agalar, Fatih; Agalar, Canan; Saygun, Oral; Daphan, Cagatay; Aydinuraz, Kuzey; Sahiner, Tayfun (Turkish Assoc Trauma Emergency Surgery, 2011)BACKGROUND We aimed to investigate the impact of C-reactive protein (CRP), interleukin (IL)-6, leptin, cortisol, and caspase-3 on the decision of terminating planned abdominal repair in secondary peritonitis. METHODS Fifteen ...