Yazar "Tekin, Saban" için Makale Koleksiyonu listeleme
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In vitro antiproliferative/cytotoxic activity of 2,3 '-biindole against various cancer cell lines
Okten, Salih; Erenler, Ramazan; Koprulu, Tugba Kul; Tekin, Saban (Tubitak Scientific & Technical Research Council Turkey, 2015)2,3'-Biindole (2) was synthesized via bromination of indole (1) with molecular bromine and underwent simultaneous dimerization. Antiproliferative and cytotoxic activity of 2 was investigated in vitro on C6 (rat brain tumor), ... -
A SAR Study: Evaluation of Bromo Derivatives of 8-Substituted Quinolines as Novel Anticancer Agents
Okten, Salih; Cakmak, Osman; Tekin, Saban; Koprulu, Tugba Kul (Bentham Science Publ Ltd, 2017)Background: Brominated 8-hydroxy, 8-methoxy, 8-amino quinolines 5, 6, 8, 9 and novel cyano 8-hydroxyquinolines 11, 12 were evaluated in vitro for their anticancer effects on various cell lines. 5,7-Dibromo-5, 7-bromo-6, ... -
Simple and convenient preparation of novel 6,8-disubstituted quinoline derivatives and their promising anticancer activities
Okten, Salih; Cakmak, Osman; Erenler, Ramazan; Yuce, Onem; Tekin, Saban (Scientific Technical Research Council Turkey-Tubitak, 2013)A short and easy route is described for 6,8-disubstituted derivatives of quinoline and 1,2,3,4-tetrahydroquinoline from 6,8-dibromoquinolines 2 and 7 by various substitution reactions. While copper-promoted substitution ...