Ara
Toplam kayıt 42, listelenen: 11-20
Synthesis, characterization, and SAR of arylated indenoquinoline-based cholinesterase and carbonic anhydrase inhibitors
(Wiley-V C H Verlag Gmbh, 2018)
We report the synthesis of bromoindenoquinolines (15a-f) by Friedlander reactions in low yields (13-50%) and the conversion of the corresponding phenyl-substituted indenoquinoline derivatives 16-21 in high yields (80-96%) ...
Theoretical Study of Synthesis of 1,3-dibromonaphthanlene
(Chem Soc Pakistan, 2018)
Naphthalene derivatives have been attracted the interest for synthesis of natural products having biological properties. Elimination reaction of tetrabromonaphthalene (1) resulted in the formation of 1,3-dibromonaphthalene ...
The inhibition effect of garlic-derived compounds on human immunodeficiency virus type 1 and saquinavir
(Wiley, 2018)
Garlic has been used as a traditional medicine to treat various diseases. Garlic reduces the risk of some diseases. This protective effect is due to the organosulfur compounds of garlic. The aim of this study was to ...
An investigation of the olive phenols activity as a natural medicine
(Food & Drug Adminstration, 2018)
The natural antioxidants of olive oil have phenolic structure and their activities are related to the formation of stable derivatives. In this study, the single components of the phenolic fraction of olive oil (1,4-hydroquinone, ...
Simple and convenient preparation of novel 6,8-disubstituted quinoline derivatives and their promising anticancer activities
(Scientific Technical Research Council Turkey-Tubitak, 2013)
A short and easy route is described for 6,8-disubstituted derivatives of quinoline and 1,2,3,4-tetrahydroquinoline from 6,8-dibromoquinolines 2 and 7 by various substitution reactions. While copper-promoted substitution ...
SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors
(Assoc Pharmaceutical Teachers India, 2019)
Background: The inhibition of both hydrolysis products of acetylcholine (ACh), Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), is essential for successful treatment of Alzhemier patients. Objectives: This ...
Synthesis, characterization, crystal structures, theoretical calculations and biological evaluations of novel substituted tacrine derivatives as cholinesterase and carbonic anhydrase enzymes inhibitors
(Elsevier Science Bv, 2019)
The six and seven hydrocycle membered disilylanilino acridine (tacrine) analogues (9-11) were synthesized by one-pot procedures. The structures of novel silyl tacrine derivatives were characterized by NMR spectroscopy, ...
The adaptation of the pedagogical knowledge and skills survey into Turkish: Validity and reliability study
(Mehmet Tekerek, 2019)
This research aims to adapt the Pedagogical Knowledge and Skills in Teaching (PKST) survey developed by Wong, Chong, Choy and Lim (2012) to Turkish. The participants of the study are 830 4th year students of education ...
Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties
(Wiley-V C H Verlag Gmbh, 2019)
The synthesis, characterization, aggregation behavior, theoretical studies, and investigation of antimicrobial, antidiabetic, and anticholinergic properties of 4-(2-(5-amino-4-(4-bromophenyl)-3-methyl-1H-pyrazol-1-yl)eth ...
Synthesis of novel cyano quinoline derivatives
(Pergamon-Elsevier Science Ltd, 2015)
6,8-Dibromo-1,2,3,4-tetrahydroquinoline (2) and 3,6,8-tribromoquinoline (3) were converted into the corresponding cyano derivatives via copper assisted nucleophilic substitution reactions. While bromination of 6-bromo-8- ...