Ara
Toplam kayıt 4, listelenen: 1-4
In vitro antiproliferative/cytotoxic activity of 2,3 '-biindole against various cancer cell lines
(Tubitak Scientific & Technical Research Council Turkey, 2015)
2,3'-Biindole (2) was synthesized via bromination of indole (1) with molecular bromine and underwent simultaneous dimerization. Antiproliferative and cytotoxic activity of 2 was investigated in vitro on C6 (rat brain tumor), ...
Simple and convenient preparation of novel 6,8-disubstituted quinoline derivatives and their promising anticancer activities
(Scientific Technical Research Council Turkey-Tubitak, 2013)
A short and easy route is described for 6,8-disubstituted derivatives of quinoline and 1,2,3,4-tetrahydroquinoline from 6,8-dibromoquinolines 2 and 7 by various substitution reactions. While copper-promoted substitution ...
SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors
(Assoc Pharmaceutical Teachers India, 2019)
Background: The inhibition of both hydrolysis products of acetylcholine (ACh), Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), is essential for successful treatment of Alzhemier patients. Objectives: This ...
Synthesis Of Brominated Quinolines
(Yildiz Technical Univ, 2015)
this study, bromination reactions of 1,2,3,4-tetrahydroquinoline by molecular bromine and aromatization reactions of brominated tetrahydroquinolines were reinvestigated. Optimal reaction conditions were established for ...