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Öğe The Investigation of Serum Estrogen, Progesterone, AMH and IGF-1 Profiles in Lactating and Non Lactating Mares after Altrenogest Administrations(2020) Polat, İbrahim Mert; Korkmaz, Ömer; Elifoğlu, Taha Burak; Pir, İlknur Yağcı; Çolakoğlu, Hatice Esra; Pekcan, MertThe objective of this study is to follow up the follicular growth in ovaries until mating by ultrasonography to determine of pregnancy rates, serum estrogen, progesterone, AMH and IGF-1 concentrations in mares which synchronized with altrenogest and to compare the obtained data with non-lactating mares. The study was carried out during breeding season while ovaries were active; lactating mares were included in Group 1 (n = 8) and non-lactating mares in Group 2 (n = 8). In both groups, synchronization was performed by administration of altrenogest (Regumate®) and prostaglandin F 2 alpha (PGF2?). Dominant follicle diameters of non-lactating mares were found to be greater than those of lactating ones. During the study, estrogen, progesterone, AMH and IGF-1 levels were significantly lower in the lactating mares. The non- lactating mares were found to have a first pregnancy conception rate (75%), similar to that of lactating mares (62%) (x2=1.54, P=0.62). It was concluded that in the mares synchronized with altrenogest, the presence of lactation and the foal are significantly influences ovarian activities, ovarian steroid levels, AMH and IGF-1 levels. Therefore, in order to increase pregnancy rates in lactating mare, sexual cycle synchronization with altrenogest are considered to be a suitable method.Öğe Postmastectomy life-threatening hypersensitivity reactions induced by rifamycin sv in companion animals: Evaluation of 7 cases(Ataturk Universitesi, 2018) Çolakoğlu, Hatice Esra; Polat, İbrahim Mert; Yazlık, Murat Onur; Çolakoğlu, Ekrem ÇağatayDrug-induced hypersensitivity and adverse symptoms related to the high mortality remain as a major problem for veterinary practitioners. Although application of Rifamycin SV without intradermal susceptibility tests have been commonly used in wound management in veterinary medicine, there is no literature about this subject. In cases presented here, neoplastic masses on the mammary glands of queens (n=3) and bitches (n=4) were removed by mastectomy. Subcutaneous Rifamycin SV was performed intra- and post-operatively. After the multiple subcutaneous usage of Rifamycin SV, acute symptoms including hypersensitivity reactions such as facial and sublingual swelling, hypersalivation, respiratory distress, tachycardia, acute vomiting, erythema and itchiness around the face, seizures and ataxia developed. In conclusion, although Rifamycin SV provides better healing effects on incision line, veterinary practitioners should consider the serious side effects of subcutaneous Rifamycin SV usage after gynaecological surgeries in companion animals. © 2016 Ataturk Universitesi. All rights reserved.