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    Predictive Factors for Muscle Weakness in Rheumatoid Arthritis
    (2022) Önder, Mustafa Erkut; Kılıçarslan, Ayşegül; Keskin, Esra Dilek; Bodur, Hatice
    Objective: We aimed to determine muscle strength in patients with rheumatoid arthritis (RA) and several factors including structural\rjoint damage that may affect decrease in muscle strength. The relations between muscle strength and quality of life and functional disability were examined. Material and Methods: Seventy five RA patients and 51 controls\rwere involved. Demographic characteristics, body mass index, waist circumference, 25-hydroxy vitamin D, and patient global assessments of disease activity (PGA) were documented. Disease Activity Score-28 (DAS28),\rVisual Analog Scale-Pain (VAS-pain), Health Assessment Questionnaire\r(HAQ) and the Rheumatoid Arthritis Quality of Life Questionnaire\r(RAQoL) were calculated. Radiographs of the hands were evaluated by van\rder Heijde modified Sharp score (vdHSS). Grip strength of both hands was\rmeasured by Jamar dynamometer. Results: Demographics (age, gender)\rwere not different between RA patients and control group. Grip strength of\rpatients with RA (22.79±18.58) was lower than control group (26.00±11.25,\rp=0.04). There was a significant correlation with grip strength and disease\rduration, tender joint count, VAS-pain, PGA, DAS28, HAQ, RAQoL, erosion and narrowing score (p<0.05). DAS28 and erosion score were associated\rwith grip strength in multivariate analyses p<0.05). Conclusion: This study\rshowed that RA obtains decreased muscle strength, impaired function and\rquality of life. Joint space narrowing and disease activity are the main parameters that affect muscle strength.\r