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    Acupuncture reduces the postoperative pain in teeth with symptomatic apical periodontitis: a preliminary randomized placebo-controlled prospective clinical trial
    (Quintessence Publishing Co Inc, 2019) Arslan, Hakan; Ahmed, Hany Mohamed Aly; Yildiz, Ezgi Doganay; Gundogdu, Eyup Candas; Seckin, Fatih; Arslan, Sumeyye
    Objective: Endodontic treatment generally results in a wide range of postoperative pain intensity. The aim of this study was to investigate the effect of preoperative acupuncture on postoperative pain in molar teeth with symptomatic apical periodontitis. Method and Materials: Thirty patients having symptomatic apical periodontitis with a preoperative and percussion pain of visual analog scale (VAS) more than 60 were included in this study. The patients were randomly distributed into two groups; G1, real acupuncture; and G2, placebo (mock acupuncture). After 15 minutes of application, root canal treatment was performed. A logistic regression analysis was used to determine the variable(s) (group, age, gender, tooth number, preoperative pain, preoperative percussion pain, and radiographic status) that controls the postoperative pain significantly. Chisquare, Mann Whitney U, and independent t tests were per-formed to analyze the data, and the level of significance was set at .05 (P = .05). Results: A regression analysis demonstrated that the group variable had the most significant effect on postoperative pain at day 1 (P = .003). Results showed that acupuncture reduced the preoperative and percussion pain levels significantly more than placebo group at all day intervals (P < .05). For postoperative pain at the 7-day follow-up, the pain ranged from "mild" to "no pain" in G1, compared with "moderate" to "minimal" in G2. Only one patient required postoperative analgesics in the acupuncture group compared to eight patients for placebo. Conclusions: Preoperative acupuncture can be beneficial in reducing postoperative pain in teeth with symptomatic apical periodontitis.
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    Regenerative Endodontic Procedures in Necrotic Mature Teeth with Periapical Radiolucencies: A Preliminary Randomized Clinical Study
    (Elsevier Science Inc, 2019) Arslan, Hakan; Ahmed, Hany Mohamed Aly; Sahin, Yavuz; Yildiz, Ezgi Doganay; Gundogdu, Eyup Candas; Guven, Yahya; Khalilov, Ruslan
    Introduction: This preliminary study compared clinical and radiographic outcomes of regenerative endodontic procedures (REPs) with that of conventional root canal treatment (CRCT) in necrotic mature teeth with periapical radiolucencies. Methods: Fifty-six mature necrotic teeth with large periapical radiolucencies were distributed into 2 groups: group 1, REPs and group 2, CRCT (n = 28/group). Clinical and radiographic follow-up assessments were undertaken up to 12 months. Statistical analysis was performed using the independent samples t test and the chi-square test, and the level of significance was set at P = .05. Results: With a follow-up rate of about 73.4% of the total patients for 12 months, favorable clinical and radiographic outcomes were found in 92.3% and 80% in REPs and CRCT groups, respectively, and the difference was not statistically significant (P > .05). Half of the teeth treated with REPs responded to the electric pulp test. Conclusions: Regenerative endodontic procedures have the potential to be used as a treatment option for mature teeth with large periapical radiolucencies.