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    Colonization, translocation and antibody response in experimental Campylobacter infection of chickens
    (Scientific Technical Research Council Turkey, 2002) Yardimci, H.; Erdeger, J.; Akan, M.; Yildirim, M.
    In this study we examined factors affecting the colonization of campylobacters in chick intestines, colonization times and elicited immune responses. In chicks, infected orally by minimal infective dose (100) (MID100), colonization in the intestines was observed to reach 100% during the 3-week period following C. jejuni and C. coli inoculation. When the SDS-PAGE protein profiles of the inoculated and isolated strains were examined similarities of 98.3% among C. jejuni strains and 98.5% among C. coli strains were determined. The results obtained from the ELISA tests performed with blood sera in the group infected with C. jejuni and in the control group for the 2nd, 3rd and 4th weeks were 0.27-0.25, 0.22-0.18 and 0.27-0.17, and the group infected with C. coli and the control group were 0.28-0.25, 0.24-0.19 and 0.32-0.18. After the immunoblotting analyses, specific bands that have molecular masses of 61, 47.5, 29.8 and 25.6 kDa were identified from C. jejuni strains and 62.5, 48 ve 31 kDa from C. coli strains, respectively.
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    The prevalence, colonization sites and pathological effects of gastric helicobacters in dogs
    (Scientific Technical Research Council Turkey, 2002) Diker, K.S.; Haziroglu, R.; Akan, M.; Çelik, S.; Kabakci, N.
    The prevalence and colonization sites of Helicobacter slap. in the stomachs of dogs, and their association with gastric pathology were investigated. Scraping cytology, culture, urease test and histology were used to detect helicobacters in the stomachs of necropsied dogs. Gastric Helicobacter spp. were detected in 103 (84.4%) of 122 dogs from I month to 14 years of age. The uncultured spiral organisms seen in the most of stomachs were designated as H. heilmannii. Microscopical examination of stained mucosal scrapings was found to be superior for the diagnosis of gastric helicobacters. Six (4.9%) spiral organisms were isolated from 122 stomachs and all were identified as H. felis. Helicobacter spp. were detected in the fundus, corpus and antrum of 103, 101 and 53 dogs, respectively. Organisms were denser in the fundus and corpus than in the antrum, Histological changes comparable to mild chronic gastritis or chronic active gastritis were found in 56.3% of Helicobacter positive dogs and 47.4% of Helicobacter-negative dogs. H. felis was found only in dogs with chronic active gastritis.