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    Effects of oral contraceptives with low-dose estrogen and desogestrel on leptin concentrations
    (Sci Printers & Publ Inc, 2002) Sagsöz, N.; Akcay, F.; Bayram, M.
    OBJECTIVE: To evaluate short-term leptin concentrations in women who use low-dose oral contraceptives. STUDY DESIGN: From 15 women without medical problems, venous blood samples were taken: basal, between days 3 and 5 of menstruation, and in the third month. The Human Leptin Radioimmunassay Kit (Linco Reseach, Inc., St. Charles, Missouri) was used for leptin measurement. Statistical analysis was done with the Wilcoxon test. RESULTS: The average patient age was 30.1 +/- 6.7 years. The basal leptin concentrations and leptin concentrations at the third month were 22.17 +/- 8.85 and 23.04 +/- 6.77 ng/mL, respectively. This increase was not statistically significant. CONCLUSION: Oral contraceptives with low-dose estrogen and desogestrel do not affect leptin concentrations in a three-month period.