Yazar "Akgul, M. H." seçeneğine göre listele

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    Diffusion-weighted imaging measurements of central smell regions in COVID-19 patients: insular gyrus, corpus amygdala, and thalamus
    (Verduci Publisher, 2023) Burulday, V.; Muluk, N. bayar; Akgul, M. H.; Sayar, M. S.
    OBJECTIVE: The aim of this study was to investigate central smell centers with cranial magnetic resonance imaging (MRI) diffusion-weighted imaging (DWI) in COVID-19.PATIENTS AND METHODS: This retrospec-tive study evaluated cranial MRI images of 54 adults. The experimental group (Group 1), con-sisting of 27 patients with positive COVID-19 real-time Polymerase Chain Reaction (RT-PCR) assays, was compared to the control group (Group 2), comprising 27 healthy con-trols without COVID-19. The apparent diffu-sion coefficient (ADC) values were measured in the corpus amygdala, thalamus, and insular gyrus in both groups. RESULTS: Thalamus ADC values of the COVID-19 group were significantly lower com-pared to the control group bilaterally. Howev-er, no differences were found in the insular gy-rus and corpus amygdala ADC values between the two groups. Positive correlations were ob-served between the insular gyrus and cor-pus amygdala ADC values and the thalamus ADC values. Insular gyrus ADC values (right) were higher in females. Left insular gyrus and corpus amygdala ADC values were higher in COVID-19 patients with smell loss. Right in-sular gyrus and left corpus amygdala ADC values were lower in COVID-19 patients with lymphopenia.CONCLUSIONS: Diffusion restriction in ol-factory areas can be considered an obvious indicator that the COVID-19 virus affects and damages the immune system at the neuro-nal level. Given the urgency and lethality of the current pandemic, acute onset odor loss should be considered a high suspicion-adhe-sive index for patients with SARS-CoV-2 infec-tion. Therefore, the sense of smell should be considered and evaluated simultaneously with other neurological symptoms. DWI should be widely used as an early imaging method for central nervous system (CNS) infections, espe-cially in relation to COVID-19.
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    Preoperative and postoperative ultrasound elastography findings of the sciatic nerve in patients with unilateral lumbar foraminal disc herniation: a pre-test and post-test design
    (Verduci Publisher, 2022) Burulday, V; Celebi, U. O.; Ogden, M.; Akgul, M. H.; Dogan, A.; Ozveren, M. F.
    OBJECTIVE: The aim of this study was to compare preoperative and postoperative findings of the sciatic nerve by using B-mode ultrasound. strain elastography (SE), and shear wave elastography (SWE) in patients with unilateral lumbar foraminal disc herniation. PATIENTS AND METHODS: In this prospective study group, patients with complaints of foraminal disc herniation due to one level (L4-5 or L5-S1) were included. Preoperative and postoperative (one month after surgery) B-mode ultrasound, SE. and SWE findings of the affected sciatic nerve in patients who underwent unilateral spinal decompression surgery were compared. Evaluations were performed on the axial plane from the gluteal region using a convex probe of 5-9L MHz. The reference method used to assess nerve root compression was 1.5-T Magnetic Resonance Imaging (MRI). RESULTS: A total of 20 patients (9 males, 11 females) with a mean age of 46.2 +/- 13.1 years were included. The cross-sectional area (CSA), diameter, SWE values of the sciatic nerve were significantly higher in the affected side compared to those of the non-affected side (all for p<0.05). Blue and blue-green were the most common color codes in the affected side while green and green-yellow-red were the most common color codes in the non-affected side. The CSA, diameter. and SWE values of the sciatic nerve decreased after the surgery in the affected side (all for p<0.05), nonetheless. those did not differ in the non-affected side (all for p>0.05). CONCLUSIONS: Lumbar decompression surgery decreases the sciatic nerve diameter, CSA, and stiffness of the sciatic nerve.