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Öğe Burnout syndrome in medical faculty students(Klinik Psikiyatri Dergisi, 2022) Akkoyun, Ayşe Zeynep; Aksu, Elif; Eker, Zeynep; Mutlu, Hilal; Uyar, Mustafa; Göbekçi, Burak TaylanObjective: In this study, it was aimed to show the level of burnout , the factors related to burnout in Afyonkarahisar Health Sciences University School of Medicine students.Method: Data; sociodemographic data form was collected through Maslach Burnout Inventory, Beck Depression Inventory, Beck Anxiety Inventory and Beck Hopelessness Inventory. The burnout level of medical students was first examined within the framework of personal and demographic variables. Afterwards, the sample was divided into two groups as preclinical (grades 1, 2 and 3) and cli-nical (grades 4, 5 and 6). The relationship between burnout and depression, anxiety and hopelessness levels was investigated between the groups and in the whole sample.Results: The results of the analysis showed us the following: There are significant diffe-rences in terms of burnout according to the variables of gender, age, class, frequency of going to the hometown, choosing the faculty, living with whom and the average daily amount of sleep. In addition, significant relationships were found between the sub-dimensions of burnout and the levels of depres-sion, anxiety and hopelessness. Among these para-meters, depressive symptoms were found to be asso-ciated with burnout at a higher level. In addition, no significant difference was found in any area of burnout between the preclinical and clinical groups.Conclusion: Our study determined that the burnout levels of medical students are high. It is thought that this study contributed to revealing the factors that lead doctor candidates to burnout.Öğe Effects of Gold Nanoparticles on Angiogenesis in A Chick Chorioallantoic Membrane Model(BEZMIALEM VAKIF UNIV, 2020) Cirik, Samet; Elesad, Musa; Basar, Ebrar; Aksu, Elif; Erdem, Muaz; Yildiztekin, Faruk; Menekse, SinanObjective: Today, nanotechnology is widely used in many fields because of its ability to alter the structure of molecules at the atomic level. Metallic nanoparticles attracted great attention from researchers because of their unique properties. Based on the notable features of gold nanoparticles (AuNPs), they have long been evaluated as a potential diagnostic tool for several cancers and for drug delivery applications. Angiogenesis is the development of new vessels that support embryonic up growth and critically modulate many biological processes through adulthood. The inhibition of angiogenesis causes regression of development and metastasis of malign tumours. In this study we aim to examine the effects of AuNPs on angiogenesis in an in vivo chick chorioallantoic membrane (CAM) model. Methods: We applied 20 mL concentrations of AuNPs solution to 24 eggs of the CAM on the fifth day. After then, we evaluated results macroscopically on the 6th and 7th days. Results: In our study, we observed that AuNPs induced angiogenesis. Conclusion: We suggest that AuNPs may not be ideal nanoparticles to make biosensors due to increasing angiogenesis during the course of cancers.