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  • Küçük Resim
    Öğe
    Effects Of Ankaferd Blood Stopper-Reinforced Platelet-Rich Fibrin Membrane On Guided Tissue Regeneration In Experimental Bone Defects
    (2019) Özer, Taha; Aktaş, Alper; Karahan, Siyami
    Background and Aim: To evaluate the effects of AnkaferdBlood Stopper added platelet-rich fibrin administered incranial bone defects created in rabbits via histomorphometricassessment.Materials and Method: Four circular 5 mm defects werecreated in the crania of 16 New Zealand rabbits. Each defect ineach animal received one of four treatments: no treatment (ECgroup), platelet-rich fibrin administration (PRF group), AnkaferdBlood Stopper added platelet-rich fibrin administration(PRF ABS group) and collagen membrane administration (CMgroup). Histomorphometric assessment was conducted at 4and 8 weeks after surgery.Results: Between-group comparisons of the new bone arearevealed significant differences between the PRF ABS groupand the remaining three groups at 4 weeks. The new bonearea was significantly larger at 8 weeks than at 4 weeks in allgroups.Conclusion: The use of Ankaferd Blood Stopper in conjunctionwith platelet-rich fibrin improves bone healing, strengthens themembrane property of platelet-rich fibrin and promotes betterossification.