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Yazar "Apan, Teoman" seçeneğine göre listele

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    The antimicrobial susceptibility of Moraxella species other than Moraxella catarrhalis
    (Turkiye Klinikleri, 2015) İşeri, Latife; Apan, Teoman; Şahin, Esra
    Objective: Although Moraxella species are members of the normal respiratory flora, some species, including M. catarrhalis, M. osloensis, M. nonliquefaciens, and M. lacunata, can cause serious infections in humans. The purpose of this study was to investigate the antimicrobial susceptibility of Moraxella species other than M. catarrhalis. Material and Methods: The study included 17 M. osloensis, 18 M. lincolnii, and three M. nonliquefacie, isolated from 100 nasopharyngeal samples. The isolates were identified by conventional methods. Identification to the species level was performed by a RapID NF Plus identification kit (Remel, USA). The antimicrobial susceptibility of the isolates was examined for ampicillin, amoxicillin/clavulanic acid, gentamicin, ceftazidime, ciprofloxacin, erythromycin and trimethoprim-sulfamethoxazole using the disk diffusion method. The results were evaluated according to guideline published by the Clinical and Laboratory Standards Institute. ?-Lactamase production was tested using nitrocefin discs. Results: The resistance rates of isolates were between 3% and 8% for trimethoprim-sulfamethoxazole, amoxicillin/clavulanic acid. Inhibition zone diameters for ampicillin of 41% of M. osloensis, 33% of M. nonliquefaciens, and 11% of M. lincolnii isolates were relatively small (?15 mm). Five M. osloensis (29%) and one M. nonliquefaciens, isolates were beta lactase positive. Conclusion: Moraxella species other than M. catarrhalis can cause serious infections in humans. Therefore, we suggest that Moraxella species other than M. catarrhalis should be included in surveillance studies. © 2015 by Türkiye Klinikleri.
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    Öğe
    Besin elleyicilerinin burun mukozalarından izole edilen stafilokokların biyotiplendirilmesi ve çeşitli antimikrobiklere duyarlılıkları
    (2006) Apan, Teoman; Yıldırım, Murat; Abut, İşeri Latife
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  • Yükleniyor...
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    The characteristics of nasopharyngeal Streptococcus pneumoniae in children attending a daycare unit
    (Edizioni Int Srl, 2008) Abut, Latife Iseri; Apan, Teoman; Otlu, Baris; Caliskan, Ahmet; Durmaz, Riza
    S. pneumoniae is a component of normal nasopharyngeal flora in children. Nasopharyngeal colonization in children attending daycare units has an important effect on the spread of S. pneumoniae. In this study, we aimed to investigate colonization status, antimicrobial susceptibility, and clonal relatedness of the S. pneumoniae strains in children attending a daycare unit. One hundred and six nasopharyngeal swabs were collected from 25 children attending a daycare unit in an 8-month period. S. pneumoniae was identified by a conventional method. Antibacterial sensitivities of the strains were tested by disc diffusion method. Pulsed field gel electrophoresis (PFGE) was used to analyze the clonal relationship of the strains. A total of 25 (23.5 %) S. pneumoniae strains were identified from 106 nasopharyngeal swaps. S. pneumoniae growth was detected in at least one culture of the 19 children (colonization rate; 76%). Seven of the 25 strains (28%) showed resistance to penicillin, 5 (20%) were resistant to trimethoprim-sulfomethoxsazole. The other tested antibiotics were almost effective. The clonal relationship among strains was found as 54.5%. The highest rate of strain entry was in the winter months with strains of opaque colonies, which are known to be more pathogenic. However, the spreading rate among the children was the highest in the summer months and the strains detected in these months had transparent colonies with more transmitting characteristics. Therefore, to prevent S. pneumoniae infection in closed crowded areas, the summer months should not be overlooked.
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    Comparison of the antimicrobial effect of heavy silicone oil and conventional silicone oil against endophthalmitis-causing agents
    (Medknow Publications, 2014) Örnek, Nurgül; Apan, Teoman; Oğurel, Reyhan; Örnek, Kemal
    Purpose: To conduct an in vitro experimental study comparing the effectiveness of conventional silicone oil and heavy silicone oil against endophthalmitis-causing agents. Materials and Methods: The antimicrobial activity of conventional silicone oil (RS OIL 5000) and heavy silicone oil (heavySil 1500) was tested. The antimicrobial effects of both silicone oils were determined by the growing capability of the microorganism. Results: The number of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans decreased to zero levels at the second day of inoculation in heavy silicone oil. In conventional silicone oil, the microorganisms survived longer than in heavy silicone oil. Conclusion: Heavy silicone oil seems to be more effective than conventional silicone oil against endophthalmitis-causing agents. © 2005 - Indian Journal of Ophthalmology.
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    Effect Of Ciprofloxacin As An Adjunctive Antibiotic On Periodontal Clinical Parameters And Crevicular Fluid Interleukin-8 And Soluble Intercellular Adhesion Molecule-1 Levels In The Treatment Of Generalized Chronic Periodontitis
    (2013) Olgun, Ebru Erdemir; Apan, Teoman; Keçeli, H. Gencay
    Amaç: Kronik periodontitisli bireylerde birleşik siprofloksasin (SIP) tedavisinin klinik periodontal parametreler, dişeti oluğu sıvısı (DOS) interlökin-8 (IL-8) düzeyi ve çözünebilir interselüler adezyon molekülü-1 (sICAM-1) düzeyi üzerine etkisini değerlendirmek. Bireyler ve Yöntem: Çalışmaya kronik periodontitisli yirmi sekiz birey dahil edildi. Hastalar iki tedavi grubuna ayrıldı. Bir gruba sadece diş yüzeyi temizliği ve kök yüzeyi düzleştirmesi (DKYD) yapılırken (DKYD grubu), diğer gruba DKYDne ek olarak sistemik olarak siprofloksasin (SIP) verildi (DKYDSIP grubu). Hastalar tedaviden önce (başlangıç) ve tedaviden bir ve üç ay sonra muayene edildi. Her randevuda klinik periodontal parametreler ölçüldü, DOS örnekleri toplandı ve DOS içerisindeki IL-8 ve sICAM-1 düzeyleri ölçüldü. Bulgular: Her iki grupta da tüm klinik periodontal parametrelerin başlangıca göre üç aylık değerlendirmelerde düştüğü gözlendi. DKYDSIP grubunda toplam IL-8 düzeyinin ve DOS hacminin başlangıçta, birinci ve üçüncü aydan daha fazla olduğu tespit edildi. DKYD grubunda, başlangıca gore üçüncü ayda DOS hacmi azalırken, sICAM-1 düzeyinde çalışma süresi boyunca anlamlı bir değişiklik gözlenmedi. Sonuç: Orta şiddetli kronik periodontitis tedavisinde her iki yöntem de etkili bulundu. Tek başına DKYDne kıyasla, DKYDne ilave olarak SIP kullanılması IL-8 düzeyini azalttı. Bu çalışmadaki tedavi yöntemleri ile DOS içerisindeki sICAM-1 düzeyi arasında anlamlı bir ilişki bulunmadı.
  • Yükleniyor...
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    Investigation of antibacterial activity of drugs used in enuresis treatment
    (Logos Medical Publishing, 2012) Boybeyi, Özlem; Apan, Teoman; Günal, Yasemin Dere; Aslan, Mustafa Kemal; Soyer, Tutku
    Objective: An in vitro study was designed to evaluate the antibacterial activity of desmopressin (DP), oxybutynin (OX), imipramine (IP), and doxazosin (DX), which are used commonly in enuresis treatment. Material and Methods: To investigate the antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis; the drugs were dispensed to tubes with physiologic saline (PS) or brain-heart broth (BHB). BHB was followed for 6 days and PS for 20 days. Antibacterial activity was examined using in vitro Time-kill method. Bacteria colonies were counted daily from PS and BHB media as colony-forming units (CFU) and evaluated by bacteri-growth graphs. Results: In BHB, none of the drugs affected growth of any bacteria. In PS, E. coli growth increased initially with DP, DX and IP and then decreased on the 5th day. Growth of E. coli was seen to continue in PS without drug on the 5th day. For DX and IP, S. epidermidis growth in PS first increased then decreased. In all PS media, growth of P. aeruginosa was seen to increase gradually. Conclusion: DP, DX and IP decreased growth of E. coli in PS, but did not prevent bacterial growth completely. Drugs used in enuresis treatment have no antibacterial activity for the bacteria evaluated in the current study. © Cocuk Cerrahisi Dergisi. All rights reserved.
  • Yükleniyor...
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    Massive oculofacial myiasis infestation with Lucilia sericata
    (Mosby-Elsevier, 2009) Çavuşoğlu, Takir; Apan, Teoman; Eker, Esabil; Vargel, İbrahim; Saray, Aydin
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  • Yükleniyor...
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    Molecular characterization of rotaviruses in mid-western Turkey, 2006-2007
    (Versita, 2010) Altındiş, Mustafa; Banyai, Krisztian; Kalayci, Raike; Gülamber, Cihangir; Köken, Resit; Apan, Teoman; Aykurt, Pınar
    Vaccines against rotaviruses are now available in numerous countries, including Turkey. As the vaccines may show various efficiencies against different type specificities and routine vaccination in infants might result in selection and immune escape of wild-type rotavirus strains, strain surveillance has been initiated before and during the vaccine introduction. We aimed to provide corresponding information on local strain prevalence in Anatolia, mid-western Turkey during the introduction of rotavirus vaccines. Stool samples positive for group A rotavirus by commercial enzyme immunoassay were subjected to reverse transcription-polymerase chain reaction based genotyping of the outer capsid antigens, VP7 and VP4, determining G and P type specificities respectively. Among 36 fully and 5 partially typeable strains we detected genotype G1, G2, and G9 VP7 specificities and genotype P[4], P[6] and P[8] VP4 specificities in 5 individual and 4 mixed combinations. The most common strain was G2P[4] (n=17), followed by G9P[8] (n=9). Other strains were G1P[8] (n=2), G2P[8] (n=2), G1+2P[8] (n=2), G9P[4] (n=1), G2+9P[8] (n=1), G4+9P[6] (n=1), and G2P[4+8] (n=1). Partially typed strains included 2 G1P[NT] and 3 G2P[NT] strains. Our data may help determine a baseline of the rotavirus genotype prevalence in Turkey and see if changes in the incidence of individual strains will be observed after routine use of vaccine.

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