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    Comprehensive microsurgical anatomy of the jugular foramen and review of terminology
    (Elsevier Sci Ltd, 2001) Tekdemir, I.; Tuccar, E.; Aslan, A.; Elhan, A.; Ersoy, M.; Deda, H.
    The microsurgical anatomy of the jugular foramen was studied in 12 formalin preserved cadavers (24 foramina) and 40 dry-skulls (80 foramina). The jugular foramen was exposed by microsurgical dissection with drilling from a superior to inferior direction. Observations regarding dural architecture of the jugular foramen and relationships between neurovascular structures passing through the foramen were noted in cadavers. Normal bony construction of the foramen and its variational anatomy were examined in dry-skull specimens. Using photographs and drawings, the anatomy of the jugular foramen is presented and related terminology is discussed in the light of a literature review. (C) 2001 Harcourt Publishers Ltd.
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    The Physiological And Dna Damage Response Of In The Lichen Hypogymnia Physodes To Uv And Heavy Metal Stress
    (CORVINUS UNIV BUDAPEST, 2020) Hamutoolu, R.; Derici, M. K.; Aras, E. S.; Aslan, A.; Cansaran-Duman, D.
    This work aims to determine the response of Hypogymnia physodes (L.) Nyl. (hooded tube lichen) collected in an unpolluted site (Yenice Forest in Karabiik, Turkey) to stress conditions. In the present study, the effect of exposure to different heavy metals (Cd+2, Pb+2, and Cr+6) for different durations and UV radiations dosages on lichen was examined at the physiological and molecular levels. The effects of stress conditions were determined in the case of different parameters concerning heavy metal, protein, chlorophyll, and carotenoid contents and changes in the DNA profiles. According to the results obtained that exposure to heavy metals and UV radiations leads to a physiological response in a concentration and dose-dependent manner through differences in chlorophyll, protein content in heavy metals and UV treated lichen specimen. Furthermore, changes in RAPD assay and DNA methylation analysis showed that homologous nucleotide sequences in the genome from untreated and stress conditions treated lichen specimen showed different band patterns and methylation under heavy metals and UV stress. The results determined that lichen specimen suggest as a possible bioindicator able to measure the biological effects of heavy metal pollution and damage to UV radiation.
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    The utility of F-18-FDG PET/CT in solitary fibrous tumors of the pleura
    (Elsevier Doyma Sl, 2016) Tazeler, Z.; Tan, G.; Aslan, A.; Tan, S.
    Objective: To demonstrate the utility of F-18-FDG PET/CT in the differentiation of benign and malignant solitary fibrous tumors of the pleura (SFTP). Materials and methods: A retrospective review was performed on the F-18-FDG PET/CT data from 17 patients with histopathologically diagnosed benign or malignant SFTP. The size, side of SFTP, presence of necrosis, calcification, pleural effusion, hilar lymphadenopathy (LAP), density on CT images (Hounsfield unit-HU), and F-18-FDG uptake (SUVmax) were recorded and compared in order to detect malignant SFTP. Statistical significance was set as p < 0.05. Results: The difference in size, presence of necrosis, and hilar LAP on CT images were statistically significant (p = 0.004, p < 0.001, p = 0.015, respectively) in a comparison of benign and malignant SFTPs. The mean HU of benign SFTP was 46.16 +/- 5.52 HU, and for malignant SFTP it was 35.03 +/- 4.61 HU (p = 0.003). The mean SUVmax was 3.02 +/- 1.02 for benign SFTP and 4.89 +/- 2.12 for malignant SFTP (p = 0.021). A cut-off value of >= 7 cm for size, <= 39.81 HU for density, and >= 3.47 for SUVmax was obtained by ROC analysis for detecting malignant SFTP. Conclusions: F-18-FDG PET/CT may have a limited role in diagnosing malignant SFTP in suspected patients. (C) 2015 Elsevier Espana, S.L.U. and SEMNIM. All rights reserved.