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Öğe In vitro evaluation of E. coli and S. epidermidis adhesion on dressing materials used in hypospadias repair(Springer Verlag, 2014) Soyer T.; Bostanoğlu E.; Aslan M.K.; Boybeyi O.; Demirbilek M.; Göçmen J.S.Background: An in vitro study was performed to evaluate the adherence of Escherichia coli and Staphylococcus epidermidis to different dressing materials. Methods: Hydrophyl gauze swab (GS), sterile flax swab (FS), and their nitrofurazone (Furacin®) absorbed forms (GSF and FSF), sterile paraffin-covered gauze with chlorhexidine acetate (0.5 %) (Bactigrass®, BG), and semipermeable transparent film gauze (Tegaderm®, TG) were used in the study. A 1 cm 2 of each material was placed in culture plates, and E. coli ATCC 25922 and S. epidermidis ATCC 12228 were suspended in each plate. After 24, 48 h, and 1 week of incubation period, colony counts were calculated in colony-forming units (CFU) per square centimeter unit. Bacterial adhesion was compared between groups, and each dressing material was also compared for different incubation periods (24, 48 h, and 1 week). Results: The colony counts were significantly decreased in GSF and FSF groups (Kruskal-Wallis test, p < 0.05). There was no difference for E. coli adhesion in GS, FS, BG, and TG groups (p > 0.05). The significant difference detected for S. epidermidis adhesion in the first 24 to 48 h could not be detected at the end of a 1-week period. There was no statistical difference in groups when compared for 24-, 48-h, and 1-week periods of incubations (Wilcoxon signed-rank test, p > 0.05). In BG group, E. coli adhesion was increased, and S. epidermidis adhesion was decreased without a significant difference at the end of a 1-week period (p > 0.05). Conclusions: Nitrofurazone absorbed sterile gauze materials have less bacterial adhesion. In vitro adhesion of E. coli and S. epidermidis did not differ between the 24-h and 1-week period. E. coli adhesion to BG can be increased if the duration of dressing prolonged up to a 1-week period.Level of Evidence: Not ratable. © 2013 Springer-Verlag Berlin Heidelberg.Öğe Infected urachal cyst mimicking incarcerated umbilical hernia: A case report(Logos Medical Publishing, 2011) Dere Günal Y.; Aslan M.K.; Boybeyi Ö.; Soyer T.Urachal cysts are rare in infants and usually asymptomatic. They may present with clinical manifestations when became infected. Ultrasonography (USG) and computed tomography are considered to be the best diagnostic procedures. A case of infected urachal cyst with a presumptive diagnosis of incarcerated umbilical hernia, is presented to evaluate the clinical findings and differential diagnosis of urachal cysts. A 2.5 month-old male infant admitted to our department with complaints of irritability, fever, umbilical bulging and periumbilical erythema. US evaluation is reported as incarcerated umbilical hernia. During exploration an urachal cyst was found and total excision was performed. The postoperative course was uneventful. Infected urachal cysts may cause clinical findings resembling those of incarcerated umbilical hernias. Infected urachal cysts should be kept in mind in infants presenting with umbilical hyperemia, erythema and tenderness, so as to establish accurate diagnosis and treatment. © 2011 Logos Medical Publishing . All Rights Reserved.Öğe Investigation of antibacterial activity of drugs used in enuresis treatment(Logos Medical Publishing, 2012) Boybeyi Ö.; Apan T.; Günal Y.D.; Aslan M.K.; Soyer T.Objective: An in vitro study was designed to evaluate the antibacterial activity of desmopressin (DP), oxybutynin (OX), imipramine (IP), and doxazosin (DX), which are used commonly in enuresis treatment. Material and Methods: To investigate the antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis; the drugs were dispensed to tubes with physiologic saline (PS) or brain-heart broth (BHB). BHB was followed for 6 days and PS for 20 days. Antibacterial activity was examined using in vitro Time-kill method. Bacteria colonies were counted daily from PS and BHB media as colony-forming units (CFU) and evaluated by bacteri-growth graphs. Results: In BHB, none of the drugs affected growth of any bacteria. In PS, E. coli growth increased initially with DP, DX and IP and then decreased on the 5th day. Growth of E. coli was seen to continue in PS without drug on the 5th day. For DX and IP, S. epidermidis growth in PS first increased then decreased. In all PS media, growth of P. aeruginosa was seen to increase gradually. Conclusion: DP, DX and IP decreased growth of E. coli in PS, but did not prevent bacterial growth completely. Drugs used in enuresis treatment have no antibacterial activity for the bacteria evaluated in the current study. © Cocuk Cerrahisi Dergisi. All rights reserved.Öğe The prevalance of enuresis nocturna among 6-10 year-old primary school children in Kırıkkale(Logos Medical Publishing, 2011) Soyer T.; Boybeyi Ö.; Aslan M.K.; Durmuş G.; Çakmak Z.A.; Ensari C.Objective: A cross-sectional study was performed to evaluate the prevalence of enuresis nocturna (EN) among 6-10 year-old primary school children in Kırıkkale. Material and Method: Children (n:1500) aged between 6-10 years were included in the study. Questionnaires were answered by the parents to evaluate the demographic and voiding characteristics, time of toilet training, dysfunctional voiding (DV) symptoms, prevalence of EN, methods and results of EN treatment. DV score (DVS) validated for Turkish children were surveyed and scores greater than 8.5 were considered significant. Results: Children (n:1372) who completed the questionnaire were included in the study. The mean age of students was 8.27 years (M: F: 707:659). EN was noted in 11.4 % (n:157, group 1) of children. EN history was noted in 37.5 % (n:515, group 2) of children, and 51.1 % (n:700, group 3) of them had never EN. Toilet training was completed after 5 years of age in 5.2 % of the students with EN and 1.3 % of the children without EN (p<0.05). The mean DVS was 8.8 (1-28), 3 (1-16) and 2 (1-16) in Groups 1,2, and 3, respectively. DVSs greater than 8.5 were noted in 45.2 %, 4.5 % and 1.6 % in these 2 groups (p<0.05), respectively. In Group 2, 42.9 % EN cases were cured spontaneously whereas 57.1 % of them were cured with treatment. Supportive treatment was recommended for 80.2 % of the children, while 19.1 % of the children had medical treatment. Desmopressin (30 %), oxybutinin (26.6 %) and imipramine (20 %) were used in 3.82 % of the children. The 24.4 % of the parents found supportive treatment effective. Parents found medical and alarm treatment effective in 20 % and 16.6 % of the cases, respectively. Conclusion: The prevalence of enuresis was 11.4 % among 6-10 year-old primary school children in our province. DV symptoms were more frequent in children with EN. Nearly half of the children with EN had been never consulted to a physician. No standard mode of follow-up and treatment was noted for these children. © 2011 Logos Medical Publishing. All right reserved.Öğe Re: Evaluation of contralateral kidney, liver and lung after extracorporeal shock wave lithotripsy in rabbits(Elsevier Inc., 2013) Senyucel M.F.; Boybeyi O.; Ayva S.; Aslan M.K.; Soyer T.; Demet A.I.; Cakmak M.A.[No abstract available]Öğe Serum procalcitonin level in monitorization of surgical site infections in neonates(Ondokuz Mayis Universitesi, 2016) Boybeyi O.; Soyer T.; Akbas O.T.; Guzoglu N.; Aslan M.K.; Gunal Y.D.; Aliefendioglu D.A retrospective study was performed to evaluate the role of white blood cell (WBC), C-reactive protein (CRP) and procalcitonin (PCT) levels in the follow-up and treatment of surgical site infections (SSI) in neonates. Neonates who underwent surgical intervention (n: 34) were evaluated for gestational age, sex, diagnosis, inflammatory markers (WBC, CRP, PCT), clinical findings, results of cultures and response to antimicrobial treatment. Records of 34 neonates and 36 surgical interventions were included to the study. Twenty (58.8%) of patients had SSI. Postoperatively CRP, WBC and PCT levels were increased (77%, 77%, 77% respectively) in patients with SSI. Postoperatively CRP, and WBC levels were increased (57% and 64% respectively) in patients without SSI. In conclusion, CRP levels and WBC count were significantly increased in 77% of cases after surgery. Increased PCT levels were detected only in patients with SSI. PCT levels may be considered as the most valuable marker to monitor SSI in neonates after surgery. © 2016 OMU.