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    Anostomose Covered by Mesh: Can We Prevent Leakage with New Instrumantation Methods?
    (Nature Publishing Group, 2014) Ay, Aybala Agac; Sozen, Vural; Ay, Ahmet; Yanik, Serdar; Daphan, Cagatay Erden
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    Effects of melatonin and dexpanthenol on antioxidant parameters when combined with estrogen treatment in ovariectomized rats
    (Springer, 2013) Turgut, Ozan; Ay, Aybala Agac; Turgut, Hulya; Ay, Ahmet; Kafkas, Samet; Dost, Turhan
    The purpose of the study was to assess whether it is possible to reduce the oxidative damage using antioxidant agents combined with hormone replacement therapy after menopause. In this prospective experimental study, 50 mature female Wistar albino rats weighing 270-310 g were used. Rats were divided into the following six groups: (1) Ovx group (n = 7): the animals underwent bilateral ovariectomy. No drug was administered following bilateral ovariectomy. (2) Ovx + E (2) group (n = 7): bilateral ovariectomy + 17 beta-estradiol (100 mu g/kg/day); (3) Ovx + E (2) + MT5 group (n = 7): bilateral ovariectomy + 17 beta-estradiol (100 mu g/kg/day) + melatonin (5 mg/kg/day); (4) Ovx + E (2) + MT20 group (n = 7): bilateral ovariectomy + 17 beta-estradiol (100 mu g/kg/day) + melatonin (20 mg/kg/day); (5) Ovx + E (2) + Dxp250 group (n = 7): bilateral ovariectomy + 17 beta-estradiol (100 mu g/kg/day) + dexpanthenol (250 mg/kg/day); (6) Ovx + E (2) + Dxp500 group (n = 7): bilateral ovariectomy + 17 beta-estradiol (100 mu g/kg/day) + dexpanthenol (500 mg/kg/day), and the activity of these antioxidative enzymes and oxidative stress products were measured. Enzymatic activity levels of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase(GSH-Px), and glutathione reductase and levels of free radicals (malondialdehyde (MDA) and nitric oxide) were both analyzed. We observed an increase in the level of GSH activity, but no significant differences in levels of CAT, SOD, and GSH-Px enzymatic activity and in levels of free radical MDA following 17 beta-estradiol or additional antioxidant treatment (melatonin or dexpanthenol). Despite the present study indicating that the addition of melatonin and dexpanthenol into the hormone replacement therapy regimen may contribute to the antioxidant effect of estrogen, the existence of limited data in this field indicates that further studies are warranted.
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    İnguinal Kitle Ayırıcı Tanısında Nuck Kanal Hidroseli
    (2015) Ağaç, Aybala Ay; Halaçlar, Bülent; Ay, Ahmet; Turgut, Ozan
    Kadın popülasyonunda Nuck kanalı hidroseli oldukça nadir bir durum olup, parietal peritonun Nuck kanalına invajinasyonu olarak da tanımlanabilir. Bu makalede kadın olguda Nuck kanalı hidroseli sunuyoruz. Otuz dokuz yaşında kadın hasta son üç aydır, dış merkezde verilen antibiyoterapiye rağmen büyüme gösteren inguinal kitle ile başvurdu. Nuck kanal hidroseli saptanan hasta ameliyat edilerek defekt yüksek ligasyonla onarıldı. Inguinal kitlelerin ayırıcı tanısında oldukça nadir görülen bu antitenin, özellikle herni ile uyumsuz inguinal kitle saptanan kadın hastalarda akılda tutulmasının önemli olduğu görüşündeyiz
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    Risk Factors for Perioperative Anxiety in Laparoscopic Surgery
    (Soc Laparoendoscopic Surgeons, 2014) Ay, Aybala Agac; Ulucanlar, Haluk; Ay, Ahmet; Ozden, Mustafa
    Background and Objectives: Our aim is to investigate the anxiety status of the patient before elective cholecystectomy and to analyze the relation between the level of anxiety for a given operation type (laparoscopic and open cholecystectomy) and the corresponding demographic and social data. Methods: A total of 333 patients undergoing cholecystectomy due to cholelithiasis were included in the study; 218 patients (66.1%) received laparoscopic cholecystectomy and 115 patients (33.9%) were treated with open cholecystectomy. The Beck Anxiety Inventory was given to all patients to be completed. We evaluated levels of anxiety in 3 groups as follows: 0 to 15, low to mild anxiety; 16 to 25, moderate anxiety; 26 to 63, severe anxiety. The following patient information remained confidential and was recorded: age and sex, associated disease, civil status, educational status, having open/laparoscopic cholecystectomy, previous knowledge of the operation, job status, economic status, health insurance, and having a child in need of care. Results: The following criteria were determined: the most determinant factors in differentiating between the score groups were having a low level of education, being of the female sex, being single, and having laparoscopic operation; the factors of being a homemaker and over the age of 25 years were determined to have significant effects. Conclusions: When analyzing the results that may appear during the intraoperative and postoperative period, understanding preoperative anxiety, analyzing the risk factors in depth, and taking the necessary precautions are all considerations that need to be the primary objectives of operators who are involved with laparoscopic, endoscopic, and robotic surgery.