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Öğe Assessment of sapheno-femoral junction continence in patients with primary adolescent varicocoele(Springer-Verlag, 2003) Karadeniz-Bilgili, M.Y.; Basar, H.; Simsir, I.; Ünal, B.; Batislam, E.Background. Although there is much evidence supporting a relationship between primary varicocoele and venous incompetence of the saphenofemoral junction in adults, there is no evidence for such a relationship during adolescence. Because of the effect of age and future occupation (standing upright for long periods) on the aetiology, pathogenesis and frequency of varicose veins of the lower extremity and incompetence of saphenofemoral junctions in adulthood, a comparison during adolescence is appropriate. Objective. On the basis of a close physiopathological and haemodynamic relationship between primary varicose veins and primary varicocoele, we decided to evaluate the competence of the saphenofemoral junctions in a selected group of adolescents affected by primary varicocoele and compare these results with age-matched healthy adolescents. Materials and methods. Twenty-five adolescents with primary varicocoele and 23 age-matched healthy controls were included in the study. In all cases physical examination and colour Doppler US was used to diagnose or exclude the presence of primary varicocoele and to evaluate the continence of the saphenofemoral junction. Results. On the right side, 10 of 25 varicocoele patients and on the left side 11 of 25 varicocoele patients had incompetence of the saphenofemoral junction. For the control patients the incidence was 2/23 on the right side and 4/23 on the left side. The difference is statistically significant. Conclustions. We demonstrated high concurrence of varicocoele and valvular incompetence of the saphenofemoral junction in a particular adolescent group. We suggest clinical examination and US assessment of the saphenofemoral junctions of adolescents affected by varicocoele in order to detect the early diagnosis of venous insufficiency of the lower limbs among these patients.Öğe Can facet joint infiltrative analgesia reduce postoperative pain in degenerative lumbar disc surgery?(Soc Espanola Neurocirugia, 2008) Bademci, G.; Basar, H.; Sahin, S.; Ozcakir, S.; Anbarci, H.; Evliyaoglu, C.; Keskil, S.Objective. Perioperative analgesia effects the postoperative course of pain. The purpose of this study was to evaluate its possible relation with the consumption of dolantine and analgesics and the facet-induced pain and postoperative pain score in degenerative disc surgery. Methods. We employed perioperative intra- and perifacet bupivacaine infiltration technique to reduce the postoperative pain after lumbar disc surgery. The study was randomized and observer blinded enrolling 40 American Society of Anesthesiologists physical status class I-II patients scheduled for elective degenerative lumbar disc surgery. The patients were divided into two groups of 20 of which Group 1 underwent injection of bupivacaine into the subcutaneous and muscular layers around the incision site, while Group 2 underwent additional intra- and perifacetal joint infiltration. Postoperatively, the patients were provided with a programmed patient-controlled pump which was only activated on demand to infuse dolantine for the next 24 hours. In the postanesthesia care unit the delay for analgesia and the dose of dolantine used were recorded. Results. There was no statistical significance between these two groups regarding postoperative visual analoque scale scores. The time before the first analgesic request was significantly longer in facet group (p = 0,006). The cumulative dolantine dose was also significantly lower in the facet group (p = 0,001). Conclusion. The results indicate that facet joint infiltrative analgesia may have an effect on the postoperative analgesic requirement and reduce the dolantine consumption.Öğe Changes of Pudendal Somatosensory Evoked Potentials (PSEP) after Sildenafil Application in Erectile Dysfunction with Diabetic Polyneuropathy (PNP)(Wiley-Blackwell Publishing, Inc, 2004) Basar, M.; Ulkatan, S.; Batislam, E.; Yilmaz, E.; Uysal-Tan, F.; Basar, H.…Öğe Combination of adenosine with prilocaine and lignocaine for brachial plexus block does not prolong postoperative analgesia(Australian Soc Anaesthetists, 2003) Apan, A.; Basar, H.; Özcan, S.; Büyükkocak, Ü.Adenosine analogues have been used by subarachnoid injection for the treatment of inflammatory and neuropathic pain. There is no data on the use of adenosine in peripheral nerve blocks. The aim of the present study was to determine the analgesic efficacy of adenosine in combination with a local anaesthetic solution for brachial plexus (BP) block With local ethics committee approval, 50 consenting adult patients undergoing upper limb surgery were enrolled in this double-blind, prospective, randomized study. Patients with a history of bronchospastic disease were excluded. Patients were instructed not to take theophylline-containing drugs and beverages for at least one day before surgery or on the first postoperative day. A supraclavicular BP block was performed by injecting a mixture totalling 35 ml made up of prilocaine 1% 10 ml and lignocaine 2% 20 ml with adrenaline 1:200 000, and adenosine 10 mg in 5 ml saline (Group 1) or 5 ml saline (Group 2) as a placebo control group. Postoperative analgesia was assessed by time to first rescue analgesia, analgesic consumption in the first 24 hours, and VAS at rest at 4, 8, 12, 16, 20 and 24 hours. Side effects were also noted. Vital signs were stable in both groups throughout the operation. There were no significant differences between the groups in onset of motor and sensory block. Time to first pain sensation from block was not significantly longer in the adenosine group (379 +/- 336 min) compared with controls (304 +/- 249 min, mean +/- SD, P=0.14). Time to first analgesic requirements and analgesic consumption in the first 24 hours were also similar in both study groups. In the present study, the addition of adenosine to local anaesthetic in brachial plexus block did not significantly extend the duration of analgesia.Öğe Comparison of three analgesics for extracorporeal shock wave lithotripsy(Taylor & Francis As, 2002) Özcan, S.; Yilmaz, E.; Büyükkoçak, Ü.; Basar, H.; Apan, A.Objective: The aim of the study was to compare the clinical efficacy of three different analgesic drugs with respect to their level of sedation, analgesia and quick mobilisation without cardiopulmonary depression, for outpatient extracorporeal shock wave lithotripsy (ESWL) procedure. Material and Methods: Sixty outpatients undergoing elective ESWL using a third generation lithotriptor were studied. The patients were randomly divided into three groups of twenty patients. All patients received midazolam (2 mg) intravenously five minutes before the procedure. In group F, fentanyl was given (I mug kg-(1) IV) at the same time with midazolam. In group D, diclofenac sodium was given (I mg kg-(1), IM) intramuscularly 45 minutes before ESWL. In group T, tramadol was given (1.5 mg kg-(1)) 30 minutes before ESWL. Arterial pressure, heart rate, respiratory rate and oxygen saturation were recorded before the procedure, after sedation, at the first minute, and every ten minutes during the procedure. Pain intensity was identified with a Visual Analogue Scale. The level of sedation was evaluated by using the Observer's Assessment of Alertness/Sedation Scale. All patients were asked to assess their satisfaction with the seven point Verbal Rating Scale before discharge. Side-effects were also recorded during the procedure. Results: The incidence of nausea and vomiting was higher in fentanyl group compared with the other groups. In patients who received fentanyl, the decrease of oxygen saturation at the first and tenth minute of the procedure was statistically significant (p < 0.05). Conclusions: Diclofenac sodium and tramadol were found to be safe and effective analgesics with lower side-effects than fentanyl.Öğe Four analgesic techniques for shockwave lithotripsy: Eutectic mixture local anesthetic is a good alternative(Mary Ann Liebert, Inc, 2003) Basar, H.; Yilmaz, E.; Ozcan, S.; Büyükkoçak, Ü.; Sari, F.; Apan, A.; Batislam, E.Background and Purpose: Various sedative and analgesic medication has been used for shockwave lithotripsy (SWL). The aim of this study was to evaluate the efficacy of different anesthesia modalities in these patients. Patients and Methods: One hundred patients were randomly divided into four groups. The first (Group F) received fentanyl 1 mug/kg intravenously (IV), the second (Group D) received diclofenac sodium 1 mg/kg-intramuscularly (IM), the third (Group T) received tramadol 1.5 mg/kg IM, and the fourth (Group E) was given 15 g of eutectic mixture local anesthetic (EMLA) cream containing lidocaine and prilocaine. After routine preoperative evaluation, all patients received midazolam 2 mg IV 5 minutes before lithotripsy for sedative premedication. In all groups, a supplemental 25-mug bolus of fentanyl was administered IV when patients complained of pain, moved, or grimaced in response to the shockwaves. Pain intensity was evaluated on a 0- to 100-mm visual analog scale (VAS). The level of sedation was determined using the Observer's Assessment of Alertness/Sedation (OAS/S). Side effects such as bradypnea, oxygen desaturation, bradycardia, pruritus, and nausea and vomiting were recorded. Results: There were no statistically significant differences among the four groups with regard to VAS, OAS/S scores, or side effects. In Group F, the mean arterial pressure was decreased significantly at 10 and 20 minutes. The patients in this group also manifested a decrease of oxygen saturation at the first, tenth, and twentieth minutes and the end of SWL. Conclusion: Application of EMLA cream was as safe and effective as fentanyl, diclofenac, and tramadol,. and reduction of the fentanyl dose during SWL was possible.Öğe Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy(Elsevier Science Inc, 2003) Yilmaz, E.; Özcan, S.; Basar, M.; Basar, H.; Batislam, E.; Ferhat, M.Objectives. To evaluate the efficacy of music on sedation in extracorporeal shock wave lithotripsy (ESWL) treatment to compare its anxiolytic effects with those of midazolam. Methods. Ninety-eight urolithiasis patients were randomly divided into two groups. Hemodynamic parameters, including mean arterial pressure, heart rate, respiration rate, and oxygen saturation, were recorded in all patients. In 50 patients (group 1), 2 mg of midazolam was administered intravenously 5 minutes before ESWL. In group 2 (n = 48), music chosen by the patients was listened to with a headset and continued during the treatment. The visual analog scale (0 to 100 mm), Observer's Assessment of Alertness/Sedation Scale, State and Trait Anxiety Inventory-Trait Anxiety test, and State and Trait Anxiety Inventory-State Anxiety test were administered for the evaluation of pain, sedation level, and patient anxiety. Results. For the hemodynamic parameters, a statistically significant decrease in mean arterial pressure was noted at the end of the ESWL procedure in group 2 and in oxygen saturation from the 10th minute to the end of the treatment in group I. Although the visual analog scale, Observer's Assessment of Alertness/Sedation Scale, and State and Trait Anxiety Inventory-State Anxiety test did not show statistically significant differences, the State and Trait Anxiety Inventory-Trait Anxiety score was found to be lower in the music group (group 2) than in the midazolam group (group 1). Conclusions. With the anxiolytic effects of music, ESWL can be performed more effectively with the patient in a comfortable state. Listening to music by patients during the ESWL session is a feasible and convenient alternative to sedatives and anxiolytics.Öğe OREXIN EXPRESSION IN PROSTATE(Wiley-Blackwell Publishing, Inc, 2010) Basar, M. M.; Han, U.; Cakan, M.; Alpcan, S.; Basar, H.[Abstract No tAvailable]Öğe Perioperative intravenous adenosine infusion to extend postoperative analgesia in brachial plexus block(Lippincott Williams & Wilkins, 2003) Apan, A.; Özcan, S.; Büyükkocak, Ü.; Anbarci, O.; Basar, H.Background and objective: Adenosine infusions have been shown to reduce requirements of anaesthetics, to decrease the need for postoperative analgesics and to attenuate hyperaesthesia related to neuropathic pain. We decided to investigate the effects, beneficial or otherwise, of an adenosine infusion administered during surgery. A brachial plexus block was used to produce anaesthesia for the surgery. Methods: Sixty adults undergoing upper extremity surgery were included in the study. Brachial plexus block was performed via an axillary approach with lidocaine 1.25 % and epinephrine 1/200 000 (40 mL). Patients were randomly assigned to two groups. During surgery, saline (control) or adenosine 80 mug kg min was infused intravenously in a double-blind fashion for 1 h. Visual analogue scores every 4 h, analgesic consumption, time to first spontaneous pain sensation, time to first rescue analgesic and adverse effects were noted during the first 24 h. Results: Vital signs were stable in both groups throughout surgery. During the adenosine infusion, one patient fainted while another complained of palpitations and tightness of the chest; both patients were excluded from further analyses. The time to first sensation of pain was significantly longer in the adenosine group compared to the control group (438 +/- 387 vs. 290 +/- 227 min, P = 0.02). The time to first rescue analgesic, the visual analogue scale scores and analgesic consumption in the postoperative period were similar. Conclusions: In patients undergoing surgery with an axillary plexus block, a perioperative adenosine infusion prolongs the duration of postoperative analgesia to some extent. However, the time to first rescue analgesic, total analgesic requirements and pain scores were unchanged; the risk of potentially serious adverse effects is high. This therapy cannot be recommended.Öğe Relationship between nocturnal penile tumescance (NPT) rigi scan monitoring results, symptom scores (IIEF) and Sildenafil responses(Wiley-Blackwell Publishing, Inc, 2004) Basar, M.; Tuglu, D.; Yilmaz, E.; Basar, H.; Batislam, E.…Öğe Relationship with international index of erectile function (IIEF) and international prostate symptom scores' (IPSS) degrees in patienst with BPH after 50 years old(Wiley-Blackwell Publishing, Inc, 2004) Basar, M.; Yilmaz, E.; Unal, S.; Basar, H.; Batislam, E.…Öğe Sildenafil citrate for penile hemodynamic determination: An alternative to intracavernosal agents in Doppler ultrasound evaluation of erectile dysfunction(Elsevier Science Inc, 2001) Başar, M.M.; Batislam, E.; Altınok, D.; Yılmaz, E.; Basar, H.Objectives. To suggest a new noninvasive method for penile Doppler ultrasound (PDU) evaluation of erectile dysfunction using oral sildenafil citrate as an erection induction agent. Methods. A total of 20 patients admitted with the complaint of erectile dysfunction were evaluated by the short form of the international Index of Erectile Function. A total score of less than 25 was accepted as erectile dysfunction and PDU was performed. The initial penile study consisted of PDU examination under visual sexual stimulation (VSS), and the peak systolic velocity, end-diastolic velocity, and resistance index were recorded. Measurements of all the parameters were repeated on the same patients after intracavernosal papaverine, intracavernosal prostaglandin E-1 (PGE(1)), and oral sildenafil citrate administration, plus VSS. All patients had these four tests in the same order at weekly intervals. Sildenafil citrate was given orally 45 minutes before Doppler investigation, and patients had VSS during the waiting period. The patients were asked about their satisfaction and comfort after each test. Statistical analysis was performed using the Wilcoxon and Mann-Whitney U tests. Results. The measurements with papaverine, PGE(1), and sildenafil citrate were significantly different from those after only VSS (P < 0.008); however, the papaverine, PGE(1), and sildenafil citrate results were not different from each other according to the peak systolic velocity, end-diastolic velocity, and resistance index measurements (P > 0.008). Patients commented that although PGE(1) was the strongest erectogenic agent, sildenafil citrate was the most convenient. Conclusions. Since the results of PDU with oral sildenafil citrate in association with VSS were not statistically different, we suggest a new noninvasive erection induction method for the purpose of PDU evaluation of erectile dysfunction. UROLOGY 57: 623-627, 2001. (C) 2001, Elsevier Science Inc.Öğe Sildenafil citrate for penile hemodynamic determination: An alternative to intracavernosal agents in Doppler ultrasound evaluation of erectile dysfunction - Reply (editorial material)(Elsevier Science Inc, 2001) Basar, M.M.; Batislam, E.; Altinok, D.; Yilmaz, E.; Basar, H.…