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Öğe BÖBREK ÜSTÜ BEZLERİNİN DİFÜZYON AĞIRLIKLI GÖRÜNTÜLEME İLE NORMAL ADC DEĞER ARALIKLARININ SAPTANMASI(2019) Bilgili, Mirace Yasemin KaradenizAmaç: Sağlıklı bireylerde böbrek üstü bezine ait görünendifüzyon katsayısı değerler aralıklarının saptanması.Gereç ve Yöntem: Retrospektif olarak planlanançalışmamızda, böbrek üstü patolojisi veya endokrin patolojitanımlamayan 25 sağlıklı erişkin olgu dahil edildi. 1.5 TeslaMRG cihaz ile b 0 ve 800 s/ mm2 değerleri kullanılarak her ikiböbrek üstü bezinde ikişer kere ölçüm yapıldı. Elde edilengörünen difüzyon katsayısı değerleri istatistiksel olarakkıyaslandı ve ortalaması elde olundu.Bulgular: Ortalama 21.4 mm2 ROI ile sağ böbrek üstü bezineait ile elde olunan görünen difüzyon katsayısı ölçüm değerlerisırasıyla 1.33±0.2x10-3 mm2/s ve 1.29±0.3x10-3 mm2/s(ortalama 1.31±0.25x10-3 mm2/s) olarak saptandı. Sol böbreğeait görünen difüzyon katsayısı ölçümleri ise sırasıyla1.3±0.2x10-3 ve 1.30±0.2x10-3 mm2/s (ortalama 1.3±0.2x10-3mm2/s) olarak saptandı. Her iki adrenal için ortalama değer1.3±0.2x10-3 mm2/s olarak bulundu. Elde olunan her dörtölçüm arasında istatistiksel olarak anlamlı farklılık saptanmadı.Sonuç: Sağlıklı bireylerde mevcut MRG cihazı veprotokollerimizle elde olunan ortalama görünen difüzyonkatsayısı değerleri, belirgin yer kaplayıcı lezyon göstermeyendiffüz böbrek üstü bezi patolojilerinin değerlendirmesine ışıktutacağı inancındayız.Öğe Idiopathic Hypereosinophilic Syndrome as a Rare Cause of Stroke: A Case Report(Turkish Neurological Soc, 2021) Turğut, Esra; Alpua, Murat; Yalçın, Selim; Coşkun, Oya; Bilgili, Mirace Yasemin Karadeniz; Açıkgöz, Ergin Ayaşlıoğlu; Coşkun, ÖzlemHypereosinophilic syndrome (HES) is a rare hematological disease that causes organ damage by eosinophil infiltration in the tissue with increased eosinophil production in the bone marrow. HES is a rare but important cause of stroke. Central nervous system involvement findings can be serious and life-threatening. Eosinophil values should be examined as the cause of stroke, and hypereosinophilia should be suspected, especially in young patients with no etiology. Reported herein is a case of a 47-year-old female patient who was followed up with the diagnosis of acute cerebrovascular disease due to idiopathic HES.Öğe Olgular Eşliğinde Tedaviye Dirençli Bronkospazmın Ayırt Edici Tanısında Mounier-Kuhn Sendromu(2015) Baççıoğlu, Ayşe; Yıldırım, Eylem; Kalpaklıoğlu, Ayşe Füsun; Bilgili, Mirace Yasemin KaradenizMounier-Kuhn Sendromu (MKS), trakea ve bronşların genişlemesi, tekrarlayan solunum yolu enfeksiyonları ve bronşektazi ile karakterizedir. Burada MKS sapta- nan iki olgu nadir görülmesi nedeniyle sunuldu. Ol- guların ortak özellikleri yıllardır zor astım/KOAH tanılarıyla takip edilmeleri, radyolojik incelemelerinde bronşektazi varlığı ve bronş sekresyonlarında nadir görülen bakterilerin üremesiydi. Birinci olgu 43 ve ikinci olgu 63 yaşında kadın olup toraks radyolojisin- de trakea ve ana bronş çaplarının ileri derecede geniş olması ile tanı aldılar. Tedavi olarak birinci olguda trakeaya stent konuldu ve semptomları dü- zelmekle beraber her seferinde stent yerinden çıkıp hemoptiziye yol açınca vazgeçildi. İkinci olguda ise hipoksemisi olmamasına rağmen polistemisi vardı. Her iki olguya tedavi olarak bronkodilatör, mukolitik ve enfeksiyon kontrolü için proflaktik antibiyoterapi ve aşılarla immünizasyon uygulandı. Sonuç olarak MKS, tedaviye dirençli bronkospazmda ayırt edici tanı ola- rak akla getirilmelidir.Öğe Reproductibility of apparent diffusion coefficients measurements in diffusion-weighted MRI of the abdomen with different b values(Elsevier Ireland Ltd, 2012) Bilgili, Mirace Yasemin KaradenizPurpose: To test the reproducibility of apparent diffusion coefficients (ADC) measurements of the normal liver, kidney and spleen parenchyma with different b values. Materials and methods: Eleven healthy volunteers were imaged twice with use of the same protocol. Each DWI was performed with b-factors of 0, 100 and 500s/mm(2). The ADCs were organized according to session (1 or 2), anatomic location and repetition (twice with two different b value per session). The ADC data were analyzed with repeated-measures analysis of variance to demonstrate the influence of anatomic location, session and different b values. The coefficient of variation was calculated for each subject, b value and anatomic location, then analyzed by using repeated-measures analysis of variance. Results: There were significant differences in mean ADCs among the three anatomic locations and with different b values (P < .05). There were no significant differences in ADCs between imaging sessions 1 or 2 for both b values (P > .05). The CV values range between 7.3% and 14.7%. There were no significant differences in CV values neither between the two b values nor for the various organ locations (P > .05). Conclusion: Using the same technical parameters, patients and the same observer, CV values range between 7.3% and 14.7%. And we recommend to be careful in examination and comparison of the measured ADC values, below these limits, without knowledge technical parameters that has been used, otherwise differences that are merely because of changes in the measurement technique could be interpreted as differences because of progression of disease or therapy. (C) 2011 Elsevier Ireland Ltd. All rights reserved.Öğe Superior Mesenteric Artery Syndrome Accompanying With Nutcracker Syndrome: A Case Report(Kowsar Publ, 2014) Inal, Mikail; Daphan, Birsen Unal; Bilgili, Mirace Yasemin KaradenizIntroduction: Superior mesenteric artery syndrome is an uncommon cause of duodenal obstruction, and its manifestations are generally associated with compression on the third part of the duodenum between the abdominal aorta and superior mesenteric artery. Case Presentation: In this report, a patient is described presenting with epigastric pain and weight loss due to superior mesenteric artery syndrome. The patient has also nutcracker syndrome, which is the compression of the left renal vein between the aorta and the superior mesenteric artery at its origin. Conclusions: In addition to an appropriate clinical history, CT findings indicating decreased aortomesenteric angle and a shortened aortomesenteric distance can suggest the diagnosis for both the superior mesenteric artery syndrome and accompanying nutcracker syndrome.Öğe Vitreous Humor Diffusion Changes in Behcet's Disease and Multiple Sclerosis(Bentham Science Publ Ltd, 2018) Inal, Mikail; Sahan, Mehmet Hamdi; Ergun, Ufuk; Bilgili, Mirace Yasemin KaradenizObjective: The aim of this study is to examine the diffusional changes in the vitreous humor in multiple sclerosis and Behcet's disease. Materials and Methods: Apparent diffusion coefficient values were investigated in diffusion magnetic resonance imaging scans of a total 111 vitreous, 31 of which were Behcet's disease patients, 40 had multiple sclerosis and 40 were healthy volunteers. Then, multiple sclerosis and Behcet's disease group were statistically compared with healthy volunteers and their apparent diffusion coefficient values amongst themselves. Results: There was no significant difference in terms of age and sex distribution among the three study groups (p>0.05). While there was no significant difference between multiple sclerosis and control groups (p>0.05), apparent diffusion coefficient values of Behcet's patients were significantly lower than multiple sclerosis and control groups (p<0.001). There was no significant difference between the patients with uveitis and those without uveitis in Behcet's disease. The apparent diffusion coefficient value of 2934,3(x10(-6) mm(2)/s) had a very high sensitivity and specificity (72.42-92.5%) for the Behcet's group, and by the use of ROC curve analysis, the detected cut off value for Behcet's disease was <= 2934,3(x10(-6) mm(2)/s). Conclusion: Our study showed that diffusion values in the vitreous humor were found to be decreased in patients with Behcet's disease, in comparison with the multiple sclerosis and the control groups. To the best of our knowledge, this has not been reported before.
