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Öğe Are the Demographic Characteristics of Patients with Primary Hip Osteoarthritis Effective on Functional Improvements After Total Hip Replacement?(2017) Taşdelen, Özlem Yılmaz; Çankaya, Deniz; Yurdakul, Fatma Gül; Çakır, Yalçın; Keskin, Esra Dilek; Tabak, Yalçın; Bodur, HaticeObjective: The aim of this study was to investigate the influence of demographic features such as age, gender, body mass index (BMI), educational and employment status, place of residence and comorbidities of patients with primary hip osteoarthritis and radiographic severity on the functional improvements of the patients after total hip arthroplasty. Material and Methods: Fifty patients (41 females/9 males) with primary hip osteoarthritis were included. The radiographs were graded according to Kellgren-Lawrence system (KL). The operations were performed by the same orthopedist with the same surgical technique. Functional level was determined with hip disability and Osteoarthritis Outcome Score-Physical function Short-form (HOOS-PS) before and six months after the operation. Results: The functional levels of all the patients improved at the sixth month. Age, BMI, presence of a comorbidity, working in a job or not, place of residence (rural or city) and obesity did not influence the functional improvement rates. The males, the patients with KL grade 4 osteoarthritis and the primary school graduates showed significantly much more improvements. Conclusion: The clinical relevance of this study is that age, gender, BMI, co-morbidities, education degree, place of residence and being an employee or not does not need to be considered by physicians when recommending total hip replacement surgery after failure of conservative treatment in patients with primary hip osteoarthritis. Male patients, patients with radiographically end stage osteoarthritis and educated patients may improve much more in comparison with their counterparts.Öğe Correlations among enthesitis, clinical, radiographic and quality of life parameters in patients with ankylosing spondylitis(Taylor & Francis Ltd, 2014) Rezvani, Aylin; Bodur, Hatice; Ataman, Sebnem; Kaya, Taciser; Bugdayci, Derya Soy; Demir, Saliha Eroglu; Sertpoyraz, Filiz MeryemObjectives. To investigate the relationship between enthesitis and disease activity, functional status, fatigue, joint mobility, radiological damage, laboratory parameter and quality of life in patients with ankylosing spondylitis (AS). Methods. A total of 421 patients with AS (323 male and 98 female) who were included in the Turkish League Against Rheumatism Registry were enrolled in the study. The Bath AS Disease Activity Index (BASDAI), fatigue, the Bath AS Functional Index (BASFI), the Bath AS Metrology Index (BASMI), the Maastricht AS Enthesitis Score (MASES), AS quality of life (ASQoL), the Bath AS Radiology Index (BASRI) and erythrocyte sedimentation rate (ESR) were evaluated. Results. Enthesitis was detected in 27.3% of patients. There were positive correlations between MASES and BASDAI, BASFI and fatigue (p < 0.05). MASES was not correlated with BASRI, BASMI, ASQoL and ESR. The mean MASES score was 1.1 +/- 2.4. The most frequent regions of enthesopathies were right iliac crest, spinous process of L5 and proximal to the insertion of left achilles tendon, respectively. Conclusions. Enthesitis was found to be associated with higher disease activity, higher fatigue, worse functional status and lower disease duration. As enthesitis was correlated with BASDAI, we conclude that enthesitis can reflect the disease activity in patients with AS.Öğe Description of the registry of patients with ankylosing spondylitis in Turkey: TRASD-IP(Springer Heidelberg, 2012) Bodur, Hatice; Ataman, Sebnem; Bugdayci, Derya Soy; Rezvani, Aylin; Nas, Kemal; Uzunca, Kaan; Sivrioglu, KoncuyA web-based application patient follow-up program was developed to create a registry of patients with ankylosing spondylitis (AS) by the Turkiye Romatizma Arastirma Savas Dernegi (TRASD) AS Study Group. This study describes the methodological background and patient characteristics. The patient follow-up program is a web-based questionnaire, which contains sections on socio-demographic data, anamnesis, personal and family history, systemic and musculoskeletal examination, laboratory and imaging data and treatment. Between October 1, 2007 and February 28, 2009, 1,381 patients from 41 centers were included in the registry (1,038 males [75.2%]; mean age 39.5 +/- A 10.7 years). Mean disease duration was 12.1 +/- A 8.5 years, and mean time from initial symptom to diagnosis was 5 +/- A 6.8 years (median 2 years). HLA-B27 positivity was detected in 73.7% of 262 patients tested. Manifestations of extraarticular involvement were anterior uveitis (13.2%), psoriasis and other skin and mucous membrane lesions (6%) and inflammatory bowel disease (3.8%). The prevalence of peripheral arthritis was 11.2%. In 51.7% of patients, the Bath AS Disease Activity Index was a parts per thousand yen4. But since our patients consisted of the ones with more severe disease who referred to the tertiary centers and needed a regular follow-up, they may not represent the general AS population. Disease-modifying anti-rheumatic drugs were being used by 41.9% of patients, with 16.4% using anti-TNF agents. TRASD-IP (Izlem Programi: Follow-up program) is the first AS registry in Turkey. Such databases are very useful and provide a basis for data collection from large numbers of subjects. TRASD-IP gives information on the clinical and demographic profiles of patients, and the efficacy and safety of anti-TNF drugs, examines the impact on quality of life, and provides real-life data that may be used in cost-effectiveness analyses.Öğe Long thoracic nerve injury: Report of two cases(2006) Bodur, Hatice; Eser, Filiz; Akbulut, Lale; Han, Serdar; Atan, ÇiğdemScapular winging is lateralization of the medial border of scapula from the posterior chest wall. The main causes of winging are serratus anterior, rhomboid and trapezius muscle paralyses. The most dramatic one is serratus anterior paralysis due to long toracic nerve injury. Herein, we present two cases with long thoracic nerve injury, discuss the diagnosis and differential diagnosis of scapular winging.Öğe Predictive Factors for Muscle Weakness in Rheumatoid Arthritis(2022) Önder, Mustafa Erkut; Kılıçarslan, Ayşegül; Keskin, Esra Dilek; Bodur, HaticeObjective: We aimed to determine muscle strength in patients with rheumatoid arthritis (RA) and several factors including structural\rjoint damage that may affect decrease in muscle strength. The relations between muscle strength and quality of life and functional disability were examined. Material and Methods: Seventy five RA patients and 51 controls\rwere involved. Demographic characteristics, body mass index, waist circumference, 25-hydroxy vitamin D, and patient global assessments of disease activity (PGA) were documented. Disease Activity Score-28 (DAS28),\rVisual Analog Scale-Pain (VAS-pain), Health Assessment Questionnaire\r(HAQ) and the Rheumatoid Arthritis Quality of Life Questionnaire\r(RAQoL) were calculated. Radiographs of the hands were evaluated by van\rder Heijde modified Sharp score (vdHSS). Grip strength of both hands was\rmeasured by Jamar dynamometer. Results: Demographics (age, gender)\rwere not different between RA patients and control group. Grip strength of\rpatients with RA (22.79±18.58) was lower than control group (26.00±11.25,\rp=0.04). There was a significant correlation with grip strength and disease\rduration, tender joint count, VAS-pain, PGA, DAS28, HAQ, RAQoL, erosion and narrowing score (p<0.05). DAS28 and erosion score were associated\rwith grip strength in multivariate analyses p<0.05). Conclusion: This study\rshowed that RA obtains decreased muscle strength, impaired function and\rquality of life. Joint space narrowing and disease activity are the main parameters that affect muscle strength.\rÖğe Quality of life and related variables in patients with ankylosing spondylitis(Springer, 2011) Bodur, Hatice; Ataman, Sebnem; Rezvani, Aylin; Bugdayci, Derya Soy; Cevik, Remzi; Birtane, Murat; Gunendi, ZaferTo evaluate quality of life (QoL) and related variables in patients with ankylosing spondylitis (AS), a chronic inflammatory disease of the spine. Nine-hundred and sixty-two patients with AS from the Turkish League Against Rheumatism AS Registry, who fulfilled the modified New York criteria, were enrolled. The patients were evaluated using the Assessment of SpondyloArthritis International Society core outcome domains including Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), fatigue (BASDAI-question 1), pain (last week/spine/due to AS), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Radiology Index (BASRI), Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and two QoL questionnaires (the disease-specific ASQoL and generic the Short Form-36 [SF-36]). The mean ASQoL score was 7.1 +/- A 5.7. SF-36 subscales of general health, physical role and bodily pain had the poorest scores. ASQoL was strongly correlated with disease duration, BASDAI, fatigue, BASFI, BASMI, BASRI, MASES, pain and SF-36 subscales (P < 0.001). SF-36 subscales were also strongly correlated with BASDAI and BASFI. Advanced educational status and regular exercise habits positively affected QoL, while smoking negatively affected QoL. In patients with AS, the most significant variables associated with QoL were BASDAI, BASFI, fatigue and pain. ASQoL was noted to be a short, rapid and simple patient-reported outcome (PRO) instrument and strongly correlated with SF-36 subscales.
