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    Öğe
    Addison hastalığı ile renal tüberküloz birlikteliği
    (2019) Cesur, Salih; Hatipoğlu, Çiğdem Ataman; Bulut, Cemal; Ergün, Emine; Kırıklı, Sami; Karakök, Taliha; Yağcı, Serap
    Renal tüberküloz akciğer tüberkülozunun lenfohematojen yayılımı sonucunda gelişir. Renal tüberkülozun en önemli bulgusu steril pyüridir. Gelişmekte olan ülkelerde Addison hastalığının %10-15’inden tüberküloz hastalığı sorumludur. Tüberküloza bağlı adrenal tutulum bilateral adrenal genişleme, atrofi ve kalsifikasyon şeklinde görülebilir. Mycobacterium tuberculosis komplekse bağlı adrenal bezlerin infeksiyonu hematojen yaylılım sonucu gelişir. Klinik bulguları yıllar sonra belirgin olabilir, asemptomatik infeksiyon oldukça sıktır. Bu yazıda, önceden Addison hastalığı (adrenokortikal yetmezlik) tanısı alan 60 yaşında bir kadın hastada saptanan renal tüberküloz sunuldu .
  • Küçük Resim
    Öğe
    Five-Years Tigecycline Experience an Analysis of Real-Life Data
    (2018) Temoçin, Fatih; Tülek, Necla Eren; Hekimoğlu, Şirin; Ilgar, Tuba; Bulut, Cemal; Erdinç, Fatma Şebnem; Ertem, Günay Tuncer
    Aim: Tigecycline has been approved by the Food and Drug Administration for the treatment of complicated intra-abdominal infections, skin and soft tissue infections and community-acquired pneumonia. In our study, we examined the efficacy of tigecycline in clinical practice and reported real life data from our hospital over a period of five years. Methods: The study was conducted between 2008 and 2013 on patients who received tigecycline for longer than 48 hours in Ankara Training and Research Hospital. Clinical success was defined as clinical recovery and microbiological cure in patients who used tigecycline. Any reason for discontinuation of tigecycline treatment was considered a clinical failure. Results: In our hospital, 320 patients were administered tigecycline between 2008 and 2013. Tigecycline was mainly used for pneumonia and skin and soft tissue infections. Tigecycline was used as monotherapy in 174 patients (54.1%). The most frequently isolated agent in tigecycline-treated patients was Acinetobacter baumannii (43.4%) followed by Enterococcus (6.9%). A change in treatment was not considered necessary in 243 (75.9%) patients who received tigecycline, while it was changed in 77 patients (24.1%). Conclusion: In conclusion, the use of tigecycline can be an effective treatment choice, either as monotherapy or as a combination antibiotic therapy.
  • Küçük Resim
    Öğe
    Reliability of VITEK (R) 2 System for Identification of Yeasts: An Isolate of Candida parapsilosis Incorrectly Identified as Cryptococcus neoformans
    (Aves, 2017) Kacmaz, Birgul; Gul, Serdar; Karabicak, Nilgun; Ayaslioglu, Ergin; Bulut, Cemal; Caliskan, Okan
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