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Öğe Compass cutter for periareolar incisions(Springer, 2008) Yazici, I.; Cavusoglu, T.; Karakaya, E. I.; Vargel, I.…Öğe Cryogel scaffolds with stem cells for bone tissue engineering: an animal model(Mary Ann Liebert Inc, 2008) Boelgen, N.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guezel, E.; Piskin, E.…Öğe Electrospun spiral-wounded polycaprolactone scaffolds with or without stem cells for cranial bone defects: an animal model(Mary Ann Liebert Inc, 2008) Isoglu, I. A.; Bolgen, N.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guzel, E.; Piskin, E.…Öğe Filling cranial defects in rats: 6 months animal study(Mary Ann Liebert Inc, 2008) Aydin, H. M.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guzel, E.; Piskin, E.[Abstract No tAvailable]Öğe Lactide-PEG cryostructures with stem cells as tissue engineering scaffolds in reconstruction of cranial bone defects in rat model(Mary Ann Liebert Inc, 2008) Egri, S.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guzel, E.; Uckan, D.; Piskin, E.…Öğe Plasma D-lactate levels in diagnosis of appendicitis(Taylor & Francis Inc, 2003) Çağlayan, F.; Cakmak, M.; Çağlayan, O.; Cavusoglu, T.We investigated the possible use of D -lactate as a predictor in the diagnosis of appendicitis. C-reactive protein level (CRP) and leukocyte counts were also evaluated. Venous blood D -lactate, CRP, and leukocyte counts were measured preoperatively in 53 patients undergoing surgery for appendicitis, as well as in 20 healthy subjects. Levels of all three parameters in the surgical patients were significantly higher than in the control group ( p < .05). Previous studies have shown that venous D -lactate is more specific to the intestine than CPR or leukocyte count. Based on our data, venous D -lactate, which had the lowest false-negative rate among these laboratory parameters, may be a useful diagnostic marker for appendicitis. None of these parameters were helpful in identifying the type of the appendicitis.Öğe Simvastatin releasing novel PCL scaffolds in rat cranium defects(Mary Ann Liebert Inc, 2007) Piskin, E.; Isoglu, A.; Bolgen, N.; Griffiths, S.; Vargel, İ.; Cavusoglu, T.; Cartmell, S.…Öğe W-Plasty Technique in Tracheal Reconstruction: A New Technique?(Karger, 2008) Han, S.; Han, U.; Atinkaya, C.; Cavusoglu, T.; Osmanoglu, G.; Dikmen, E.Background: Tracheal stenosis and dehiscence of anastomosis due to excessive tension are well-known problems after long-segment tracheal resections. The aim of this study was to evaluate the efficacy of the W-plasty technique to prevent these two complications. Methods: Animals were divided into a study and a control group. Each group consisted of 6 animals. In the control group, we performed a 5-cm tracheal segment resection, and then reconstruction was performed with an interrupted technique with 6/0 Prolene sutures. In the study group, we used the W-plasty technique with 6/0 Prolene interrupted sutures. The animals were sacrificed on the 30th day postoperatively and tracheal resection including the entire anastomosis site was performed. The traction and pullout test was applied to each specimen and all the specimens were analysed histopathologically. The intraluminal diameter and the thickness of the tracheal wall at the level of anastomoses were measured by using a micrometer. The pattern of the reaction and localization were recorded. Results: The traction and pullout test results were 131.6 +/- 4.3 g and 187.5 +/- 6.4 g in the control and the study group, respectively, which was a significant difference (p = 0.004). The intraluminal diameters were 3.3 +/- 1.2 mm and 4.3 +/- 0.9 mm in the control and study group, respectively (p = 0.134). In contrast to the control group, early inflammatory and late fibroblastic reactions were negative in the study group. Conclusion: Considering the outcomes of this study, we think that the W-plasty technique has much more advantages than the standard techniques in terms of anastomosis durability and development of stenosis. Copyright (C) 2008 S. Karger AG, Basel
