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    Comparison of Multi Layer Perceptron and Jordan Elman Neural Networks for Diagnosis of Hypertension
    (Tsi Press, 2015) Turk, Fuat; Barisci, Necaattin; Ciftci, Aydin; Ekmekci, Yakup
    In this study, from 150 individuals over the age of 30 taken no drugs, sex, age, height, weight, HDL, LDL, Triglyceride, smoking and uric acid were measured. 65 of them are normal but 85 consist of the patients. This data was transferred to the computer by processing methods of quantitative analysis. Data obtained of each patient was applied Artificial Neural Network (ANN) models. The results obtained will be classified as either normal or the patient. Using Multi Layer Perceptron (MLP) neural network, 80.4% of patient individuals and 81.8% of normal individuals were classified correctly. Using Jordan Elman neural network, 85.3% of the patient individuals and 87.8% of normal individuals were classified correctly.
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    Comparison of Principal Component Analysis and Radial Basis Function Network for Diagnosis of Hypertension
    (Turgut Ozal Univ, 2012) Turk, Fuat; Barisci, Necaattin; Ciftci, Aydin; Ekmekci, Yakup
    In this study, from 150 individuals over the age of 30 taken no drugs, sex, age, height, weight, HDL, LDL, Triglyceride, smoking and uric acid were measured. 65 of them are normal but 85 consist of the patients. Data obtained of each patient was applied Artificial Neural Network (ANN) models. The results obtained will be classified as either normal or the patient. Using Principal Component Analysis (PCA), 89% of patient individuals and 88% of normal individuals were classified correctly. Using Radial Basis Function Networks (RBFN), 89% of the patient individuals and 84% of normal individuals were classified correctly.
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    Evaluation of the effect of chiropractic manipulative treatment on oxidative stress in sacroiliac joint dysfunction
    (BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2020) Kultur, Turgut; Ciftci, Aydin; Okumus, Muyesser; Dogan, Murat; Durmaz, Senay Arikan; Neselioglu, Salim; Erel, Ozcan
    Objectives: This study aims to investigate the effect of chiropractic manipulative treatment on sacroiliac joint dysfunction (SIJD) and its relationship to oxidative stress (OXS) parameters. Patients and methods: Thirty-three patients diagnosed with SIJD (20 males, 13 females; mean age 36.3 +/- 9.7 years; range, 18 to 60 years) and 30 healthy volunteers (20 males, 10 females; mean age 36.4 +/- 12.2 years; range, 20 to 57 years) were included in this cross-sectional, case-control study conducted between February 2017 and September 2017. Manipulation was applied to the patients once a week for a duration of four weeks. The patients were evaluated at pre-treatment and one month after treatment with visual analog scale, SIJD test, and total thiol, native thiol, disulphide, and ischemia-modified albumin (IMA) as OXS indicators. Results: Prior to treatment, we demonstrated that serum native thiol (mu mol/L) and total thiol (mu mol/L) levels in the patient group were lower compared to control subjects (p=0.03 and p=0.02, respectively). Serum IMA levels were higher in the patient group (p=0.01). There was no change in OXS parameters after manipulative treatment in the patient group. Conclusion: Manipulation is useful in SIJD. Thiol/disulphide homeostasis and serum IMA levels may be used to measure the OXS in patients with SIJD.
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    Reply to the Letter to the Editor for "Evaluation of the effect of chiropractic manipulative treatment on oxidative stress in sacroiliac joint dysfunction"
    (BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2020) Kultur, Turgut; Ciftci, Aydin; Okumus, Muyesser; Dogan, Murat; Durmaz, Senay Arikan; Neselioglu, Salim; Erel, Ozcan
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    Serum levels of nitrate, nitrite and advanced oxidation protein products (AOPP) in patients with nonalcoholic fatty liver disease
    (Univ Catholique Louvain-Ucl, 2015) Ciftci, Aydin; Yilmaz, Bulent; Koklu, Seyfettin; Yuksel, Osman; Ozsoy, Metin; Erden, Gonul; Cesur, Salih
    Background and study aims : Oxidative stress is increased and anti-oxidant defense mechanisms are impaired in patients with hepatosteatosis. The aim of the present study was to evaluate the serum levels of several oxidant and anti-oxidant markers in patients with nonalcoholic fatty liver disease (NAFLD). Patients and Methods : Thirty-four patients with NAFLD, and 19 healthy controls were included. In this study, we measured serum nitrate and advanced oxidation protein product (AOPP) as the oxidizing products and nitrite as the anti-oxidizing marker. Nitrate and nitrite levels were measured using a calorimetric method, and levels of serum AOPP were measured by a spectrophotometric method using a commercial ELISA kit. Results : Serum nitrate and AOPP levels were significantly higher in the NAFLD group compared to the control group. Serum nitrite and N-N levels were similar between the two groups. Serum nitrate and N-N levels were found to be significantly higher in patients with elevated ALT levels compared to patients with normal ALT levels. Serum nitrite and AOPP levels were comparable between these groups. Mean platelet volume (MPV) was significantly lower in the NAFLD group compared to the control group. Conclusions : Serum levels of oxidizing agents including nitrate and AOPP increase in patients with NAFLD. In contrast, serum nitrite, an antioxidant agent, does not adequately increase to compensate for the oxidizing effects in these patients.