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Öğe Age-based success rates after elective oocyte cryopreservation (EOC): a pooled analysis of 2281 thaw cycles(Elsevier Science Inc, 2011) Cil, A. P.; Oktay, K.…Öğe Anti-Mullerian hormone predicts affected sisters of patients with PCOS(Oxford Univ Press, 2012) Cil, A. P.; Guler, Z. B.; Kisa, U.…Öğe Comparison of IVF-ET cycles using vitrified donor versus nondonor oocytes: a pooled analysis of 705 thaw cycles(Elsevier Science Inc, 2011) Cil, A. P.; Oktay, K.…Öğe Dehydroepiandrosterone supplementation improves ovarian response and cycle outcome in poor responders(Elsevier Sci Ltd, 2009) Soenmezer, M.; Oezmen, B.; Cil, A. P.; Oezkavukcu, S.; Tasci, T.; Olmus, H.; Atabekoglu, C. S.The effect of dehydroepiandrosterone (DHEA) supplementation on cycle outcome was assessed in patients with poor ovarian response. In total, 19 poor responder patients who were scheduled to undergo a second intracytoplasmic sperm injection (ICSI)/embryo transfer cycle were enrolled and first ICSI/embryo transfer cycles were taken as the control group. All subjects were given DHEA supplementation (25 me, t.i.d.) for at least 3 months prior to their second ICSI/embryo transfer cycle. In both cycles a fixed dose of rFSH (300 IU/day) and human menopausal gonadotrophin (HMG) (75 or 150 IU/day) along with a flexible gonadotrophin-releasing hormone (GnRH) antagonist protocol were administered. A favourable decrease was noted in mean day 3 serum oestradiol concentrations after DHEA Supplementation (75.14 +/- 28.93 versus 43.07 +/- 11.77; P < 0.01). Increased number of >17 mm follicles (3 +/- 0.7 versus 1.9 +/- 1.3; P < 0.05), MII oocytes (4 +/- 1.8 versus 2.1 +/- 1.8; P < 0.05), top quality day 2 (2.2 +/- 0.8 versus 1.3 +/- 1.1: P < 0.05) and day 3 embryos (1.9 +/- 0.8 versus 0.7 +/- 0.6; P < 0.05) were achieved in DHEA-supplemented cycles. Cycle cancellation rates were reduced (5.3% versus 42.1%; P < 0.01), and the pregnancy rate per patient and clinical pregnancy rate per embryo transfer (47.4% versus 10.5%; P<0.01 and 44.4% versus 0%; P < 0.01) were improved after DHEA supplementation. DHEA supplementation might enhance ovarian response, reduce cycle cancellation rates and increase embryo quality in poor responders.Öğe Myometrial involvement of tumor-like cystic endosalpingiosis: a rare entity(John Wiley & Sons Ltd, 2008) Cil, A. P.; Atasoy, P.; Kara, S. A.Endosalpingiosis is characterized by the presence of benign glands lined by tubal-type epithelium involving the pelvic and lower abdominal peritoneum and pelvic and para-aortic lymph nodes in women. Rarely, cystiflcation can occur, resulting in a neoplasm-like mass associated with clinical manifestations, an intraoperative abnormality, or a striking finding on gross examination. Here we report the transvaginal ultrasound, magnetic resonance imaging and bistopathological appearance of an unusual case of cystic endosalpingiosis involving the right ovary and full thickness of the wall of the uterine fundus in a patient who presented with a 6-month history of menor-rhagia and pelvic pain. Clinicians should be aware of this type of uterine benign manifestation so as to refrain from overtreatment. Copyright (c) 2008 ISUOG. Published by John Wiley & Sons, Ltd.Öğe Power Doppler properties of endometrial polyps and submucosal fibroids: a preliminary observational study in women with known intracavitary lesions(John Wiley & Sons Ltd, 2010) Cil, A. P.; Tulunay, G.; Kose, M. F.; Haberal, A.Objectives To compare power Doppler flow mapping characteristics of endometrial polyps and submucosal fibroids and analyze whether two different power Doppler characteristics, single-vessel pattern and rim-like vessel pattern, can help to differentiate these focal endometrial lesions. Methods Patients suspected of having endometrial polyps or submucosal fibroids on sonohysterography were examined prospectively by transvaginal B-mode and power Doppler sonography. Single-vessel pattern and rim-like vessel pattern were considered to be characteristic of endometrial polyps and submucosal fibroids, respectively. Suspected diagnoses of the lesions according to vascular Doppler characteristics were compared with the final diagnosis following histopathological examination. Results Included in the final analysis were 49 patients with histological confirmation of the type of endometrial lesion: 32 with endometrial polyps and 17 with submucosal fibroids. Power Doppler signals were observed in 47 of these; they were not observed in two patients with endometrial polyps. Of the 32 with endometrial polyps, 26 (81.3%) endometrial polyps showed a single-vessel,P pattern, three (9.4%) showed a multiple-vessel pattern and one (3.1%) showed a scattered-vessel pattern. Of the 17 with submucosal fibroids, 12 (70.6%) showed a rim-like vessel pattern, three (17.6%) showed a multiple-vessel pattern and two (11.8%) showed a single-vessel pattern. Single-vessel pattern was associated with two false-positive cases, but there were no false-positive cases for rim-like vessel pattern. The sensitivity, specificity and positive and negative predictive values for single-vessel pattern in diagnosing endometrial polyps were 81.2%, 88.2%, 92.9% and 71.4% and for rim-like pattern in diagnosing submucosal fibroids they were 70.6%, 100%, 100% and 86.5%, respectively. Conclusions Power Doppler blood flow mapping is a valuable tool in the diagnosis of focal endometrial pathology and is useful in distinguishing submucosal fibroids and endometrial polyps. Copyright (C) 2010 ISUOG. Published by John Wiley & Sons, Ltd.
