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Öğe Characterization of Leiurus abdullahbayrami (Scorpiones: Buthidae) venom: peptide profile, cytotoxicity and antimicrobial activity(Biomed Central Ltd, 2014) Erdes, Efe; Dogan, Tugba Somay; Cosar, Ilhan; Danisman, Tarik; Kunt, Kadir Bogac; Seker, Tamay; Ozen, CanBackground: Scorpion venoms are rich bioactive peptide libraries that offer promising molecules that may lead to the discovery and development of new drugs. Leiurus abdullahbayrami produces one of the most potent venoms among Turkish scorpions that provokes severe symptoms in envenomated victims. Methods: In the present study, the peptide profile of the venom was investigated by electrophoretic methods, size-exclusion and reversed-phase chromatography and mass spectroscopy. Cytotoxic and antimicrobial effects were evaluated on a breast cancer cell line (MCF-7) and various bacterial and fungal species. Results: Proteins make up approximately half of the dry weight of L. abdullahbayrami crude venom. Microfluidic capillary electrophoresis indicated the presence of 6 to 7 kDa peptides and proved to be a highly practical peptidomics tool with better resolution when compared to conventional polyacrylamide gel electrophoresis. Mass spectroscopy analysis helped us to identify 45 unique peptide masses between 1 to 7 kDa with a bimodal mass distribution peaking between molecular weights of 1 to 2 kDa (29%) and 3 to 4 kDa (31%). L. abdullahbayrami crude venom had a proliferative effect on MCF-7 cells, which may be explained by the high concentration of polyamines as well as potassium and calcium ions in the arachnid venoms. Antimicrobial effect was stronger on gram-negative bacteria. Conclusions: This work represents the first peptidomic characterization of L. abdullahbayrami venom. Considering the molecular weight-function relationship of previously identified venom peptides, future bioactivity studies may lead to the discovery of novel potassium and chloride ion channel inhibitors as well as new antimicrobial peptides from L. abdullahbayrami venom.Öğe A Contribution to the Knowledge of the Linyphiid Spider Fauna of Turkey (Araneae: Linyphiidae)(Inst Zoology, Bas, 2013) Danisman, Tank; Cosar, IlhanThis paper reports six linyphiid spider species which are new to the Turkish araneo-fauna. Descriptive notes, drawings and photographs of Araeoncus mitriforinis Tanasevitch, 2008, Diplostyla concolor (Wider, 1834), Megalepthyphantes nebulosus (Sundevall, 1830), Neriene radiata (Walckenaer, 1841), Porrhomma microphthalmum (O. P.-Cambridge, 1871) and Walckenaeria antica (Wider, 1834) are presented.Öğe DESCRIPTION OF A NEW ZODARIINE SPIDER, ZODARION GAZIANTEPENSE SP. N., IN THE Z. SPINIBARBE SPECIES GROUP FROM TURKEY (ARANEAE: ZODARIIDAE)(Amer Entomol Soc, 2021) Danisman, Tarik; Cosar, IlhanA new species, Zodarion gaziantepense sp. n. is described from the southeastern region of Turkey. Z. gaziantepense sp. n. can be easily distinguished from all other Turkish and European representatives of the genus by the structure of a triangular-shaped median apophysis.Öğe DESCRIPTION OF THE HITHERTO UNKNOWN FEMALE OF PELECOPSIS TOPCUI (TURKES ET. AL. 2015), COMBN (ARANEAE, LINYPHIIDAE)(Amer Entomol Soc, 2020) Danisman, Tarik; Cosar, Ilhan; Ozkutuk, Recep Sulhi; Kunt, Kadir BogacIn this study, Abacoproeces topcui Turkes et. al. 2015 is shown to be an inappropriate generic assignment. The male and hitherto unknown female are redescribed and the species is transferred to Pelecopsis comb.n.Öğe First description of the females of two species of Zodarion (Araneae: Zodariidae)(Magnolia Press, 2022) Cosar, Ilhan; Danisman, Tarik; Elverici, MertThe females of Zodarion samos Bosmans, 2009 and Zodarion varoli Akp??nar, 2016 are described for the first time. Z. samos Bosmans, 2009 is further a new record to the Turkish araneofauna. Characteristic features and photographs of both species are presented, and known localities in Turkey are provided. Previous records of Zodarion rubidum Simon, 1914, and Zodarion ruffoi Caporiacco, 1951 from Turkey are based on misidentifications and shall be omitted from the national species list.Öğe Four new records for the spider fauna of Turkey (Araneae: Salticidae)(Tubitak Scientific & Technical Research Council Turkey, 2015) Cosar, IlhanFour Salticidae spider species, Euophrys sulphurea (L. Koch, 1867), Neon levis (Simon, 1871), Pellenes brevis (Simon, 1868), and Sibianor aurocinctus (Ohlert, 1865), are recorded for the first time from Turkey. Their morphology is briefly described and illustrated.Öğe A new species of Coelotes Blackwall, 1841 (Araneae: Agelenidae) from Turkey(Tubitak Scientific & Technical Research Council Turkey, 2016) Danisman, Tarik; Karanfil, Kubra Ceren; Cosar, IlhanThe species Coelotes sinopensis sp.n. is described from Sinop Province, Turkey. Differences between the new species and related species are discussed.Öğe A new species of the genus Hersiliola Thorell, 1870 from Turkey (Araneae: Hersiliidae)(Taylor & Francis Ltd, 2012) Danisman, Tarik; Sancak, Zafer; Erdek, Melek; Cosar, IlhanA new species of Hersiliola Thorell, 1870 is described from Antalya Province, Turkey. Differences between the new species and related species are discussed.Öğe A New Species Of The Genus Zodarion Walckenaer, 1826 (Araneae: Zodariidae) From Turkey(AMER ENTOMOL SOC, 2020) Danisman, Tarik; Cosar, IlhanAnew species, Zodarion izmirense sp. nov. is described and illustrated based on material collected in the Izmir Province of Turkey. Differences between the new species and the closely related Zodarion tireboluensis Danisman and Rubio, 2017 are discussed.Öğe Orchestina topcui sp n., a new spider from Turkey (Araneae: Oonopidae)(Taylor & Francis Ltd, 2012) Danisman, Tarik; Cosar, Ilhan…Öğe Six new records for the spider fauna of Turkey (Araneae: Salticidae)(Entomological Soc Turkey, Ege Univ, 2016) Cosar, Ilhan; Varol, Muhammed IsmailSix Salticidae spider species, Evarcha laetabunda (C. L. Koch, 1846), Heliophanus verus Wesolowska, 1986, Pellenes seriatus (Thorell, 1875), Plexippoides flavescens (O. Pickard-Cambridge, 1872), Pseudicius palaestinensis Strand, 1915 and Saitis barbipes (Simon, 1868) are new records for the spider fauna of Turkey. Their morphology is briefly described and illustrated.Öğe Three new Genus Records of the Spider Fauna of Turkey (Araneae: Salticidae)(Florida Entomological Soc, 2013) Cosar, Ilhan; Elverici, Mert; Danigman, Tarik; Kunt, Kadir BogacNew records of 3 genera and 3 species of Salticidae from Turkey are presented for Bianor albobimaculatus (Lucas, 1846), Dendryphantes rudis (Sundevall, 1833) and Hyllus insularis Metzner, 1999. Their morphology is briefly described and illustrated. Current knowledge on diversity of Salticidae in Turkey is also reviewed. Total number of Salticidae species recorded from Turkey now is 102.
