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Öğe A Case with Hereditary Neuropathy with Liability to Pressure Palsy(Derman Medical Publ, 2013) Dağ, Ersel; İnal, Elem; Türkel, Yakup; Gökçe, Nalan; Orkun, SevimHereditary neuropathy with liability to pressure palsy (HNPP) is an autosomal dominant disease which characterized by recurrent mononeuropathies with focal sensory or motor disturbance precipitated by minor trauma or compression. Clinically, it generally presents with painless pressure palsies, typically in the 2nd and 3rd decades of life, being a rare entity in childhood. We reported a case study of a 22 year-old female who presenting with low back pain, After detection of an Achilles reflex loss in her neurological examination and electrophysiological studies and genetic investigation was done than she diagnosed with HNPP. We want to emphasize that, the diagnosis of hereditary neuropathy with liability to pressure palsy is often delayed because it is rare in the practice of medicine and confused with polyneuropathy, careful neurological examination may be the most important factor in the diagnosis.Öğe ABSANS NÖBET İLE BAŞVURAN DYKE DAVİDOFF MASSON SENDROMU OLGUSU(2015) Türkel, Yakup; Alpua, Murat; Adıgüzel, Ahmet; Habipoğlu, Yasin; Dağ, ErselDyke Davidoff Mason Sendromu(DDMS) serebral hemiatrofinin mevcut olduğu hemiparezi ve rekürren epileptik nöbetlerle karakterize bir sendromdur. Biz de absans nöbetlerle prezente olan kranyal MR'ında hemisferik atrofinin mevcut olduğu tipik bir DDMS olgusu sunmak istedik. Olgunun çekilen elektroensefalografisinde jeneralize 3 Hz diken dalga deşarjları izlendi. Hastanın takibinde uygun antiepileptik tedavi ile nöbetleri kontrol altına alındıÖğe Attention deficit/hyperactivity disorder in adults with multiple sclerosis(Sage Publications Ltd, 2016) Alpua, Murat; Turkel, Yakup; Güneş, Nalan; Oğuztürk, Ömer; Dağ, Ersel; Yoldaş, Tahir K.…Öğe Bilateral Recurrent Optic Neuropathy with Unilateral Oculomotor Nerve Palsy in Giant Cell Arteritis(Informa Healthcare, 2013) Örnek, Nurgül; Dağ, Ersel; Büyüktortop, Nesrin; Oğurel, Reyhan; Örnek, Kemal…Öğe Cerebral Sinus Thrombosis During Pregnancy Associated with Protein S Deficiency: Report of a Rare Case(2014) Bulanık, Murat; Dağ, Zeynep Özcan; Demiray, Demet; Dağ, Ersel; Şimşek, YavuzHerediter trombofilik mutasyonlar genel popülasyonun %10unda görülür ve bir çok olgu gebelik sırasında ortaya çıkan komplikasyonlar sonucunda tanı alır. Bunlardan Protein S eksikliği nadir görülen ve şiddetli trombojenik özellikte bir herediter trombofiliadır. Protein S eksikliği eşlik eden gebelikler genelde fetal kayıpla sonuçlanır. Bu yazıda canlı doğumla son bulan gebeliği sırasında, 30. gebelik haftasında serebral sinüs trombozu geçiren ve tetkiklerinde protein S eksikliği saptanan bir olgu sunularak konu literatür bilgileri eşliğinde tartışıldı.Öğe Cognitive evaluation and quality of life assessment in patients with subjective tinnitus(Neurological Society R.O.C (Taiwan), 2016) Dağ, Ersel ; Bayar Muluk, Nuray; Karabiçak, Hasan; Arıkan, Osman Kürşat; Türkel, YakupPurpose: To investigate the effects of subjective tinnitus on cognitive functions. Methods: There were 15 patients (10 bilateral, 5 unilateral) with tinnitus who were non-psychiatric in the study group. There were 14 controls (28 ears of them) that were healthy, non-psychiatric and did not have tinnitus. We used questionnaire form; Hospital Anxiety and Depression Scale (HAD); The SF-36 Health Survey; and the Montreal Cognitive Assessment (MoCA) test to evaluate cognitive functions of the subjects. Results: In tinnitus patients, all HAD results (HAD-depression, HAD-anxiety and HAD-total) were insignificantly higher; and all SF-36 items were lower than the control group. In tinnitus group, MoCA scores (mean: 22.28 ± 3.90) were significantly lower then the control group (mean = 26.07 ± 1.74). In tinnitus group, higher MoCA scores were related to increased role limitations due to emotional problems (RE) and physical functioning (PF) values. As subjective tinnitus loudness level (STLL) values increased, HAD-Anxiety values increased and social functioning (SF) values were decreased. In well educated tinnitus patients, MoCA scores found significantly increased. Better Quality of life (QoL) results were found with better MoCA scores. The most important SF-36 items were PF, RE and social functioning (SF). Conclusion: Subjective tinnitus had negative impact not only in quality of life, but also in cognitive function of the patients. © 2016, Neurological Society R.O.C (Taiwan). All rights reserved.Öğe Pregabalin-Induced Akathisia(Sage Publications Inc, 2013) Dağ, Ersel; Gökçe, Burcu; Buturak, Sadiye Visal; Tiryaki, Duygu; Erdemoğlu, Ali Kemal…Öğe Rare side effects of valproic acid: Gingival hyperplasia, and cervical lymphadenopathy(2013) Dağ, Ersel; Demirer, Serhat ; Gökçe, Burcu ; Acar, Betül; Keçel, Hüseyin Gencal; Aylıkçı, Uğur Bahadır; Erdemoğlu, Ali KemalGingival hyperplasia is a common disorder seen in patients with epilepsy treated with phenytoin. It is rarely seen in patients taking sodium valproate therapy. Especially in mentally retarded patients, poor oral hygiene causes to the accumulation of bacterial plaque and inflammation might be occurs. Connective tissue increases due to inflammation and gingival hyperplasia is seen. We report a case of gingival hyperplasia due to valproic acid use to draw attention to rare adverse effect of this drug.Öğe Refractory status epilepticus that responded to steroid application(Duzce University Medical School, 2013) Dağ, Ersel; Acar, Betül; Kasımcan, Ömer; Erdemoğlu, Ali KemalThe minimum duration of a seizure needed to be described as status epilepticus is a matter of great debate; but many authors use a time period of 5 to 20 minutes. In refractory status epilepticus, despite treatment with conventional antiepileptic drugs, seizures continue or baseline values of consciousness between seizures do not return. Status epilepticus due to a brain tumor may be resistant to antiepileptic therapy. A case of refractory status epilepticus controlled by steroid application is presented in this report and discussed in the light of literature. © 2013 Düzce Medical Journal.Öğe Retinal nerve fiber layer thickness in patients with essential tremor(Asean Neurological Assoc, 2015) Türkel, Yakup; Örnek, Nurgül; Dağ, Ersel; Örnek, Kemal; Alpua, Murat; Oğurel, Tevfik; Ölmez, YaşarObjective: To investigate the retinal nerve fiber layer (RNFL) thickness in essential tremor (ET). Methods: Twenty-seven eyes of 27 patients with essential tremor were included in this study. Twenty-seven eyes of 27 healthy volunteers served as controls. All eyes were examined with spectral domain optical coherence tomography (OCT) (Retinascan Advanced RS-3000; NIDEK, Gamagori, Japan) using image filling software program (NAVIS-EX, NIDEK, Tokyo, Japan). Results: No statistically significant difference was detected between ET patients and control group for overall (RNFL) and foveal retinal thickness parameters. [RNFL thickness (Average thickness p=0.86, superior average p=0.22, inferior average p=0.24, nasal average p=0.06, temporal average p=0.88), foveal retinal thickness p=0.63] There was no relationship between OCT parameters and age, gender and duration of ET (all p>0.05). Conclusion: We did not find altered RNFL and foveal thickness values in patients with ET compared to controls. Retinal thickness changes do not seem to be a potentially useful biomarker in ET patients.Öğe Sneddon’s syndrome presenting with neuropathic pain(Pulse Marketing and Communications LLC, 2013) Dağ, Ersel; Gökçe, Burcu; Koçak, MukadderA 55-year-old man was admitted to us with a sense of numbness, tingling, and burning in his feet and headache, characterized as a feeling of pressure all around his head, for 1 year and aggravated in the past 3 months. The patient’s neurologic examination was normal and he had no other known diseases except for hypertension according to his medical history. During the examination, we recognized purplish lesions on the patient’s body. His kidney, liver, and thyroid function test results and vitamin B12 levels were all normal. His hematocrit level was 41.8%, platelet value was 234,000 (150,000-500,000), and sedimentation rate was 9 mm/h (0-20). Electromyography was performed and results were found to be normal. The patient was diagnosed as having small fiber neuropathy. Dermatologic examination revealed reddish blue mottling of the skin with fishnet reticular pattern on his back, on the front side of the body, and on both arms and legs, and the lesions were classified as livedo racemosa (Figure 1). Brain magnetic resonance imaging (MRI) showed subcortical hyperintense ischemic-gliotic signal changes on T2-FLAIR in the deep white matter of bilateral frontoparietal vertex, centrum semiovale, and corona radiata (Figure 2). FLAIR sequence axial MRI of the brain of our patient showed subcortical hyperintense lesions in both cerebral hemispheres. His cardiac examination was normal and minimal aortic regurgitation was seen on echocardiography. His cognitive assessment Minimental Test Score was 22, and Montreal Cognitive Assessment score was 18. Laboratory values for inflammatory markers and autoimmune antibodies including syphilis serology, lupus anticoagulants, and anticardiolipin antibodies were negative. Factor V Leiden mutation was not detected in the patient. The patient was diagnosed with Sneddon’s syndrome with the above signs and symptoms and small fiber neuropathy. Clopidogrel 75 mg and gabapentin 1200 mg was started once a day and blood pressure regulation was achieved. © 2013 Pulse Marketing & Communications, LLC.Öğe Solifenacin induced dyskinesia(2012) Dağ, Ersel; Azapoğlu, Burcu; Deniz, TurgutAşırı aktif mesane inkontinans olsun ya da olmasın urgency ile ilişkili kronik bir durumdur. Solifenazin günde tek doz kullanılan selektif antimuskarinik bir ajandır. Günde 5 mg olarak başlanır, tolere edilebilirse 10 mg’a artırılabilir. Biz burada solifenazin kullanımı sonrası ortaya çıkan ve ilacın kesilmesini takiben birkaç gün içinde ortadan kaybolan diskinezili bir olguyu sunduk.Öğe Status Epilepticus in a Patient with Amyotrophic Lateral Sclerosis(Aves, 2014) Dağ, Ersel; Şahin, Oruç; Gökçe, Burcu; Erdemoğlu, Ali KemalIntroduction: Amyotrophic Lateral Sclerosis, the most common and well-known form of motor neuron disease, is characterized by progressive degeneration of upper and lower motor neurons. Respiratory failure and aspiration due to respiratory muscle weakness is the most common causes of mortality in patients with amyotrophic lateral sclerosis. Status epilepticus is the second most frequent neurological emergency with a risk of major morbidity or mortality. Status epilepticus, due to causes such as prolonged seizures, respiratory distress, acidosis, hypoglycemia, and hypotension may lead to mortality. Case Report: A forty-eight year old male patient had been followed for 4 years with a diagnosis of amyotrophic lateral sclerosis and was referred to our clinic with the diagnosis of status epilepticus. The refractory status epilepticus patient was treated with a diagnosis of respiratory failure and the need for mechanical ventilation evolved. Conclusion: We report the development of status epilepticus in a patient with amyotrophic lateral sclerosis, and in addition to the appropriate anti-epileptic medication, ventilator support and intensive care was needed, emphasizing the life-saving procedure.Öğe Transient global amnesia after ventricular fibrillation during acute myocardial infarction(2013) Tulmaç, Murat; Şimşek, Vedat; Dağ, Ersel; Tireli, Emine; Eser, Özer; Ebinç, Haksun; Doğru, Mehmet TolgaBurada akut inferolateral miyokard infarktüsü seyrinde anında tedavi edilen ventrikül fibrilasyonu sonrası geçici global amnezi gelişen 48 yaşında bir erkek hastayı bildiriyoruz. Hekimler ventrikül fibrilasyonu ile komplike olan miyokard infarktüsü ile gelen hastalarda geçici global amnezi varlığını araştırmaya özellikle dikkat etmelidir.
