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Öğe Cognitive evaluation and quality of life assessment in patients with subjective tinnitus (2)(Neurological Society R.O.C (Taiwan), 2016) Dağ E.; Bayar Muluk N.; Karabiçak H.; Arikan O.K.; Türkel Y.Purpose: To investigate the effects of subjective tinnitus on cognitive functions. Methods: There were 15 patients (10 bilateral, 5 unilateral) with tinnitus who were non-psychiatric in the study group. There were 14 controls (28 ears of them) that were healthy, non-psychiatric and did not have tinnitus. We used questionnaire form; Hospital Anxiety and Depression Scale (HAD); The SF-36 Health Survey; and the Montreal Cognitive Assessment (MoCA) test to evaluate cognitive functions of the subjects. Results: In tinnitus patients, all HAD results (HAD-depression, HAD-anxiety and HAD-total) were insignificantly higher; and all SF-36 items were lower than the control group. In tinnitus group, MoCA scores (mean: 22.28 ± 3.90) were significantly lower then the control group (mean = 26.07 ± 1.74). In tinnitus group, higher MoCA scores were related to increased role limitations due to emotional problems (RE) and physical functioning (PF) values. As subjective tinnitus loudness level (STLL) values increased, HAD-Anxiety values increased and social functioning (SF) values were decreased. In well educated tinnitus patients, MoCA scores found significantly increased. Better Quality of life (QoL) results were found with better MoCA scores. The most important SF-36 items were PF, RE and social functioning (SF). Conclusion: Subjective tinnitus had negative impact not only in quality of life, but also in cognitive function of the patients. © 2016, Neurological Society R.O.C (Taiwan). All rights reserved.Öğe Lamotrigine induced seizures in juvenile myoclonic epilepsy(2013) Acar B.; Dağ E.; Türkel Y.Juvenile myoclonic epilepsy (JME) is a common epileptic syndrome. Before the development of the new antiepileptic drugs (AEDs) after the 1990s, Valproate (VPA) was the first-line treatment in juvenile myoclonic epilepsy. However, the frequent adverse effects and the risk for teratogenicity have resulted in a search for alternative therapies especially in women. Lamotrigine (LTG), topiramate, and levetiracetam, have been used as monotherapy or adjunctive therapy for juvenile myoclonic epilepsy in small patient series. We report a case of a thirty one-years-old female suffered from severe aggravation in myoclonic and generalized tonic-clonic (GTC) seizures after decreasing the lose of VPA and initiating LTG. © 2013 OMU.Öğe Rare side effects of valproic acid: Gingival hyperplasia, and cervical lymphadenopathy(2013) Dağ E.; Demirer S.; Gökçe B.; Acar B.; Keçel H.G.; Aylikçi U.B.; Erdemoğlu A.K.Gingival hyperplasia is a common disorder seen in patients with epilepsy treated with phenytoin. It is rarely seen in patients taking sodium valproate therapy. Especially in mentally retarded patients, poor oral hygiene causes to the accumulation of bacterial plaque and inflammation might be occurs. Connective tissue increases due to inflammation and gingival hyperplasia is seen. We report a case of gingival hyperplasia due to valproic acid use to draw attention to rare adverse effect of this drug.Öğe Refractory status epilepticus that responded to steroid application(Duzce University Medical School, 2013) Dağ E.; Acar B.; Kasimcan O.; Erdemoğlu A.K.The minimum duration of a seizure needed to be described as status epilepticus is a matter of great debate; but many authors use a time period of 5 to 20 minutes. In refractory status epilepticus, despite treatment with conventional antiepileptic drugs, seizures continue or baseline values of consciousness between seizures do not return. Status epilepticus due to a brain tumor may be resistant to antiepileptic therapy. A case of refractory status epilepticus controlled by steroid application is presented in this report and discussed in the light of literature. © 2013 Düzce Medical Journal.
