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    Comparison Between One and Two Dose Vaccine Applications Based on COVID-19 Cases with Simulation Method
    (Kırıkkale Üniversitesi, 2022) Demirbilek, Mustafa
    COVID-19 pandemic started Wuhan city in China affected world for almost one and half years and caused millions of infected and death people and great loss in economic activities. The most effective intervention strategy is vaccination to stop COVID-19 pandemic as it stopped other pandemics in history. The number of shots produced so far is insufficient for societies even though studies for developing vaccines started with the pandemic. Insufficient number of vaccines and the reasonable level protection of one-dose shot on individuals caused widespread criticisms of applications of two doses. In this study, applications of one dose and two dose vaccines are compared based on the number of cases by considering different efficacy levels, the number of shots, and delivery periods. SIR (Susceptible-Infectious-Recovered) Network model where individuals can directly interact with others only in homes, schools, and workplaces while indirectly interacting with the remainings is used to mimic the pandemic. Thirty trials are conducted for each scenario included an application of one or two dose vaccines and independent sample t tests are carried out to understand whether differences between results are statistically significant for the model a-year pandemic duration and a-million population are considered in. The application of one dose vaccine significantly decreases the number of cases compared to two doses for the 60-day delivery period.