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    Distalization of Mandibular Molars Using Mini-Plate Anchorage Fixed on Ramus: Case Report
    (Aves Press Ltd, 2006) Uysal, Tancan; Gelgor, Ibrahim Erhan; Sari, Zafer; Dolanmaz, Dogan
    Distalization of the lower molars has been one of the most difficult biomechanical problems in the orthodontic treatments. Nowadays it has become possible to move mandibular molars distally with temporary skeletal anchorage systems to correct mandibular crowding and dental asymmetries without lower premolars extraction. In this study, the efficacy and potency of mini-plates in lower molar distalization were evaluated and skeletal, dental and soft tissue changes were analyzed with cephalometric radiographs and dental casts.
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    Histomorphometric evaluation of the effects of zoledronic acid on mandibular distraction osteogenesis in rabbits
    (W B Saunders Co-Elsevier Inc, 2008) Pampu, A. Alper; Dolanmaz, Dogan; Tüz, Hakan H.; Avunduk, M. Cihat; Kisnisci, Reha S.
    Purpose: To assess the effect of systemic administration of zoledronic acid (ZA) on mineralization of newly formed bone and to determine strain-related osteoporosis on surrounding bone during lengthening of immature rabbit mandible. Materials and Methods: Eighteen New Zealand white rabbits were divided randomly into 2 groups, and bone lengthening was carried out in the left portion of the mandible through distraction osteogenesis with a rate of 0.5 mm every 12 hours for 5 days. The experimental group was administered 0.1 mg/kg ZA intravenously. The control group was given saline infusion only during operation. All animals were sacrificed at the end of the 28-day consolidation period. The mandibles of all animals were removed and regenerate was evaluated. Osteoblasts, osteoclasts, collagen fibers, and fibroblasts were marked within 0.1-mm(2) area and newly formed bone area was measured within 0.5-mm(2) area. All data were analyzed using Mann-VAiitney U test. Results: Although irregular bone destruction spots were seen in the control group, the experimental group showed regular ossification areas and significant difference between osteoblast and osteoclast numbers (P < .05). In the regenerate zone, there was considerable difference between the 2 groups in terms of osteoblast, osteoclast, and collagen amounts (P < .05). Additionally, newly formed bone areas and fibroblast count were higher in experimental group. Conclusions: The results of this study showed that ZA had positive effects on the new bone formation, which may potentially shorten the consolidation period. (c) 2008 American Association of Oral and Maxillofacial Surgeons.
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    Histomorphometric examination of long-term changes in temporomandibular joints after mandibular lengthening by distraction osteogenesis in rabbits
    (Elsevier Science Inc, 2012) Mihmanli, Ahmet; Dolanmaz, Dogan; Tuz, Hakan; Pampu, Alper; Donmez, Hasan Huseyin
    Objective. The purpose of this study was to evaluate long-term histomorphometric changes in temporomandibular joints (TMJs) of rabbits after mandibular distraction osteogenesis (DO). Study Design. Twenty-six rabbits were used in this study. Two of them served as control subjects, and the remaining 24 underwent DO procedures in their left mandibular bodies. After a latency period of 5 days, 5 mm lengthening was performed at a rate of 1 mm/d. The rabbits in the experimental group were randomly divided into 4 subgroups and killed after 1, 2, 4, and 6 months. TMJs from both sides were harvested and prepared with hematoxylin and eosin stain for histomorphometric examination under an optical microscope. Results. Compared with control subjects and nondistracted sides, fibrous articular, proliferative, and hypertrophic areas were significantly increased (P < .05) in the first 2 months in distracted sides. The changes were insignificant in the fourth and sixth postoperative months. Conclusion. Unilateral mandibular distraction of 5 mm was found to be well tolerated and no degenerative changes were observed histologically in the rabbit TMJs in the long-term period. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;113:600-603)