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    Evaluation of palatal donor site haemostasis and wound healing after free gingival graft surgery
    (Wiley-Blackwell, 2015) Keceli, Huseyin Gencay; Aylikci, Bahadir Ugur; Koseoglu, Serhat; Dolgun, Anil
    AimEvaluating effectiveness of a medicinal plant extract (MPE) in achieving haemostasis and early wound healing at free gingival graft (FGG) donor site in a randomized controlled fashion. MethodsForty patients requiring FGG at lower anterior area were randomly assigned into two groups. FGG was performed to all patients and following graft procurement; wet gauze (WG) was applied alone (control: WG group) or with MPE (test: MPE+WG group) for haemostasis. Donor site working time, bleeding (BLE), colour match (CM), pain, epithelization (EP) and sensation loss (SL) were evaluated. ResultsThirty-three participants completed a 6-month period study. In the test group, primary BLE was shorter (p<0.001) and fewer individuals showed secondary BLE during 3days (p<0.001). During the 6days, pain scores were higher in WG patients (p<0.05). Later on, no inter-group difference was observed. EP was relatively faster (p<0.001) and CM was slightly better (p<0.05) in MPE+WG group. ConclusionMPE provided faster and continuous haemostasis that made a positive contribution to the early soft tissue healing to some extent but due to limitations; further trials are needed to demonstrate the efficiency of this material.
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    Evaluation of the adjunctive effect of platelet-rich fibrin to enamel matrix derivative in the treatment of intrabony defects. Six-month results of a randomized, split-mouth, controlled clinical study
    (Wiley, 2016) Turkal, Humerya Aydemir; Demirer, Serhat; Dolgun, Anil; Keceli, Huseyin Gencay
    Aim: This study aimed to compare the results obtained with enamel matrix derivative (EMD) and EMD + platelet-rich fibrin (PRF) in the treatment of intrabony defects (IBDs) in chronic periodontitis patients. Materials and Methods: Using a split-mouth design, 28 paired IBDs were randomly treated either with EMD or with EMD + PRF. Clinical and radiographic measurements including clinical attachment level (CAL), probing depth (PD), gingival recession (GR), defect depth (DD), defect width (DW) and defect angle (DA) were recorded at baseline (BL) and at six months following therapy. Results: BL clinical and radiographic measurements were similar for EMD and EMD + PRF groups. Although postsurgical measurements revealed significant reduction for PD and CAL in both groups, no intergroup difference was detected. When EMD and EMD + PRF groups were compared, defect fill was not also statistically different. Conclusions: Both therapies resulted in significant clinical improvement in IBD treatment. Addition of PRF did not improve the clinical and radiographic outcomes.