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Öğe Analysis of Biochemical, Hormonal and Radiological Morphological Measurement Values in Patients with Empty Sella: A Clinical Study(Georg Thieme Verlag Kg, 2024) Özdemir, Alemiddin; Erdoğan, Ahmet Melih; Sevimoğlu, Özge; Durgun, Efe Barış; Ermiş, Süha Alp; Yalçın, Rümeysa; Karaca, Yusuf EminObjective This study investigated the relationship between radiological morphological findings and hormone levels in patients with empty sella. Methods Patients (32 female, 3 male) with empty sella detected on radiological images were grouped as partial empty sella (PBS) group (subarachnoid space volume < 70%) and total empty sella (TBS) group (subarachnoid space volume > 70%). Age, gender, sella volume, pituitary gland thickness, the ratio of subarachnoid space height to pituitary gland height, and diaphragm sellae diameter were measured on radiological images. All patients' blood count results, biochemistry results, and serum hormone values were recorded. Results Age, complete blood count, serum biochemistry parameters, and hormone levels were not different between PBS and TBS groups. Correlation analysis revealed a negative correlation between gender and subarachnoid space invasion volume, between gender and sagittal width of the sella turcica (ST), between cortisol level and ST axial diameter, between progesterone level and ST axial diameter, between testosterone level and ST axial diameter, between adrenocorticotropic hormone level and ST axial diameter, between TSH level and subarachnoid space invasion rate, between free T4 level and diaphragm sellae sagittal width, and between free T4 level and ST sagittal width. Conclusion This study showed that some serum hormone values may decrease when the sella tursica dimensions or the volume of subarachnoid space invading the sella tursica increase in patients with empty sella, and therefore, periodic follow-up of hormone levels and radiological images of these patients would be appropriate.Öğe Analysis of radiological measurement parameters that can predict the type of treatment to be applied in odontoid fractures: Clinical research(Wolters Kluwer Medknow Publications, 2023) Öğden, Mustafa; Erdoğan, Ahmet Melih; Karagedik, Mustafa İlker; Başer, Selçuk; Bulut, İbrahim Umud; Sevimoğlu, Özge; Yüksel, UlaşIntroduction: Although various conservative and surgical treatment methods have been proposed, treatment options for patients with odontoid fractures remain controversial. This study was conducted to determine some demographic and radiological measurement parameters that can predict treatment options in patients with odontoid fractures. Materials and Methods: The patients were separated into the surgery (-) group (n = 9) and the surgery (+) group (n = 10). Patient data were recorded of age, gender, type of odontoid fracture, morphological measurement results obtained from computed tomography images, treatment regimens, duration of stay in the hospital, and mortality rate. In the operating room, a halo-vest corset or Philadelphia-type cervical collar was applied to the surgery (-) patients after the reduction of the fracture under fluoroscopy. Anterior odontoid lag screw fixation was performed on surgery (+) patients. Results: The amount of displacement of the fractured odontoid, the distance between the C1 vertebra and the odontoid process, the angle between the posterior wall of the odontoid process and the posterior wall of the clivus, the slip angle, and the anterior to posterior width of the spinal canal were not different between the groups. No difference was determined between the groups in respect of the amount of lateral displacement of the odontoid process in the spinal canal in the axial plane and the angle of the fractured odontoid process with the C2 vertebral body. Conclusion: This preliminary study showed that the demographic data and radiological measurement parameters analyzed in the present study could not be used as predictive markers either in decision-making for treatment modality or mortality risk.