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    Disseminated tuberculosis with lymphatic, splenic and scrotal abscesses: A case report
    (2009) Ayaşlıoğlu, Ergin; Başar, Halil; Duruyürek, Nihal; Kalpaklioğlu, Füsun; Göçmen, Sedef; Ertürk, Arzu; Yılmaz, Şinasi
    Introduction: Disseminated tuberculosis can involve several organs and clinically present with a potpourri of signs and symptoms. Early diagnosis and timely initiation of proper treatment are of great importance in preventing the later complications of the disease. Case presentation: We report a case with disseminated tuberculosis who exhibited a wide spectrum of extrapulmonary involvement. The present case had lung and lymph node tuberculosis with abscess formation and remained undiagnosed for two years. Thereafter, multiple splenic abscesses developed that necessitated splenectomy, and at the final stage, he presented with scrotal abscesses. Conclusion: This paper highlights the diverse clinical appearances of disseminated tuberculosis and the significant importance of early diagnosis and treatment. © 2009 Ayaslioglu et al.; licensee Cases Network Ltd.
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    Helicobacter pylori in bronchiectasis: A polymerase chain reaction assay in bronchoalveolar lavage fluid and bronchiectatic lung tissue
    (Elsevier Science Inc, 2007) Gülhan, Meral; Özyılmaz, Ezgi; Tarhan, Gülnur; Demirag, Funda; Capan, Nermin; Ertürk, Arzu; Ahmed, Kamruddin
    Background. A number of studies have implicated an association between H. pylori and diverse extra-gastroduodenal pathologies. Chronic inflammation and increased immune response have been observed in bronchiectasis, likely gastroduodenal inflammatory diseases. H. pylori has been found in the trachea-bronchial aspirates of mechanically ventilated patients. Furthermore, the seroprevalence of H. pylori was found to be significantly higher in patients with bronchiectasis than in the control group. The present study was performed to investigate the possible role of H. pylori in the pathogenesis of bronchiectasis. Methods. Prospectively, bronchoalveolar lavage fluid (BALF) was obtained from patients with bronchiectasis (n = 26) and control (n = 20). BALF was subjected to polymerase chain reaction (PCR) to determine the presence of H. pylori and serum IgG against H. pylori was determined with micro-ELISA kit. In addition, PCR was performed to determine H. pylori in surgically removed lung tissues from patients with bronchiectasis (n = 97). Results. H. pylori DNA was not detected in the BALF or in lung tissue samples. In addition, anti-H. pylori IgG level in patients with bronchiectasis did not show statistically significant difference from that of the control. Conclusions. Our study provided evidence that there might be no direct association between H. pylori and bronchiectasis; however, the indirect role of soluble products of H. pylori could not be excluded. (C) 2007 IMSS. Published by Elsevier Inc.
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    Investigation of Pneumocystis Jiroveci Carriage in Patients with Various Lung Diseases
    (Kırıkkale Üniversitesi, 2008) Kaygusuz, Sedat; Ertürk, Arzu; Kılıç, Dilek; Konur, Özcan; Kubar, Ayhan
    Pneumocyctis jiroveci is one of the major reasons of morbidity especially in immunosuppressive individuals. Recently, a large number of asymptomatic colonization has been noted. The aim is to investigate the frequency of P. jiroveci colonization in patients (Group I) with lung cancer who do not take oral corticosteroid and the patients (Group II) with other lung problems by using immunofluorescence (IF) method and polymerase chain reaction.Incidence of P. jiroveci has been investigated in the bronchoalveolar lavage samples taken by bronchoscopy for diagnose and treatment by using IF method and P. jiroveci DNA has been defined with PCR method.In Group I, 1 (1.8%) IF and 3 (5.5%) PCR positivism (one of them is the case which is found positive by using IF method) have been acquired. In Group II, both of the methods have produced no positivism.Colonization of P. jiroveci is noted in patients with HIV negative. The fact that the cases only with lung cancer have positivity supports the idea that lung cancer is important risk factor. The patients with lung cancer should be monitored closely for prophylaxis and treatment and the treatment should not be applied to each PCR positive case.