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Öğe Clinical characteristics and response to growth hormone treatment in patients with Prader-Willi Syndrome(Karger, 2019) Evliyaoglu, Olcay; Cakir, Aydilek Dagdeviren; Bas, Firdevs; Akin, Onur; Siklar, Zeynep; Ozcabi, Bahar; Berberoglu, Merih[Abstract No tAvailable]Öğe Incidence of iodine deficiency in Turkish patients with congenital hypothyroidism(Blackwell Publishing, 2008) Evliyaoglu, Olcay; Kutlu, Alev; Kara, Cengiz; Atavci, Sevil G.Background: Turkey is located in an area of mild to moderate iodine deficiency. The aim of the present study was to investigate the incidence of iodine deficiency in patients with congenital hypothyroidism. Methods: Twenty five patients with a median age of 12 days (6 days-6 months) at diagnosis and followed for a median time of 7 months (1-60 months) were enrolled in the study. Thyroid function tests, thyroid scintigraphy, ultrasonography and urine iodine measurements of the patients and mothers were performed. Results and conclusion: Congenital hypothyroidism was diagnosed within postnatal day 13, between days 13 and 30, and after 30 days of age in 68%, 20% and 12% of the patients, respectively. At the time of diagnosis mean serum thyroid-stimulating hormone and total T4 were 85.3 +/- 27.6 mIU/L and 3.9 +/- 2.8 mu g/dL, respectively. Incidence of iodine deficiency was 36% in the patients (median, 110 mu g/L) and 88% in the mothers (median, 40 mu g/L). Thyroid scintigraphy and ultrasound were normal in all of the patients with iodine deficiency. At scintigraphic evaluation, thyroid gland was not visualized in 28% of patients; in the patients whose thyroid glands were not visualized scintigraphic ally thyroid ultrasonography indicated agenesis in 57%, and hypoplasia in 43%. In all the patients with thyroid agenesis or hypoplasia iodine levels were normal. In 36% of the patients imaging studies of thyroid gland and urine iodine measurements were normal. Despite salt iodization program, incidence of iodine deficiency is still high in patients with congenital hypothyroidism and mothers. National measures are urgently required for correction of iodine deficiency in Turkey.Öğe Life quality in girls with Turner syndrome a cross sectional study(Karger, 2008) Bideci, Aysun; Evliyaoglu, Olcay; Cetinkaya, Ergun; Aycan, Zehra; Berberoglu, Merih; Siklar, Zeynep; Yesilkaya, Ediz[Abstract No tAvailable]Öğe Rathke Cleft Cyst in Seven Year-old Girl Presenting with Central Diabetes Insipidus and Review of Literature(Freund Publishing House Ltd, 2010) Evliyaoglu, Olcay; Evliyaoglu, Çetin; Ayva, SebnemRathke cleft cysts (RCC) are benign cysts derived from remnants of Rathke cleft, and are rarely symptomatic in children. Symptoms due to RCC are associated with mass effect and pituitary hormone deficiencies. Slow growth rate of the cyst makes its incidence increase with aging. Here we report on a seven year old girl who presented with central diabetes insipidus (CDI). Her sella MRI revealed a lesion in the sellar region which grew rapidly in follow-up. She underwent microneurosurgical operation and the lesion was totally excised. Pathologic examination revealed RCC with degenerative changes. In her follow-up, growth hormone deficiency developed in addition to arginine vasopressin deficiency. Rapid growth of the cyst is not the usual course of RCC's. Mechanisms regarding the cyst growth are unclear as they are in this case. This is the youngest child to date presenting with central diabetes insipidus due to RCC. Rapid growth of RCC can cause CDI in young children.Öğe Urine iodine levels and prevelance of goitre in school children in Kirikkale(Karger, 2008) Cakir, Baris; Evliyaoglu, Olcay; Sanli, Cihat…
