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    Autologous serum effect on corneal endothelial damage in the phacoemulsification rabbit model
    (Derman Medical Publ, 2017) Usta, Gülşah; Oğurel, Reyhan; Onaran, Zafer; Pekcan, Zeynep; Oğurel, Tevfik; Karsli, Birkan; Gökçinar, Nesrin Büyüktortop
    Aim: This study used specular microscopy to evaluate the possible effects of applying autologous serum to the anterior chamber on the corneal endothelial damage created by the ultrasonic vibrations of phacoemulsification (PHACO) in rabbits. Material and Method: The study, which was approved by the Ethics Committee, involved both eyes of nine 5 month-old (about 3 kg) New Zealand genus albino male rabbits. Group 1(6 eyes) received only an application of 0.2 ml autologous serum; Group 2 (6 eyes) received only the ultrasonic vibrations for 20 seconds: and Group 3 (6 eyes) received 0.2 ml autologous serum followed by ultrasonic vibrations for 20 seconds. Measurements were made before the intervention and at the 1st and 7th days postoperatively using specular microscopy, intraocular pressure, and pachymetry metrics, and the data were compared statistically. Results: Postoperative 1st week, the cornea thickness increased from 385 mu to 445 mu in Group 2 (PHACO only) and from 398 mu to 402 mu in Group 2 (PHACO plus autologous serum). However, this difference was not statistically significant. Postoperative 1st day standard deviation (p < 0.05) and variation coefficient (p < 0.05) values of the specular microscopy parameters for Groups 2 and 3 were higher than for Group 1. Postoperative 1st week it was observed that the parameters of the three groups were similar and had returned to the preoperational values. Between the endothelial cell numbers, the cell density, the cell space average, the largest and the smallest percentage of the cell and the hexagonal cell area values, there were no statistically significant differences at the three measurement time points. Discussion: This study showed that, after the phacoemulsification process, autologous serum applied to the anterior chamber can, by positive possible effects on endothelial pump functions, reduce corneal edema without morphological changes, which can be confirmed with specular microscopy
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    Cystoid macular edema following selective laser trabeculoplasty in a patient with ocular hypertension
    (Springer, 2019) Örnek, Nurgül; Örnek, Kemal; Oğurel, Tevfik; Gökçinar, Nesrin Büyüktortop
    Purpose Presentation of a case with ocular hypertension who developed cystoid macular edema (CME) following selective laser trabeculoplasty (SLT). Case report A 62-year-old male patient who had undergone phacoemulsification surgery for traumatic cataract 9 years ago was on ocular hypertension treatment for the last 5 years. Due to uncontrolled intraocular pressure and side effect of medications, a 360 degrees SLT was performed. The patient returned with decrased visual acuity 1 week after the procedure. There was CME in the treated eye. It healed completely after topical prednisolone acetate QID and nepafenac QID for 1 week, and no recurrence was observed during follow-ups. Conclusion Cystoid macular edema may occur following SLT treatment in patients with previous traumatic cataract surgery which responds to topical treatment.