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Öğe Antimicrobial Activity of Centaura derderiifolia, Stachys aleurites and Anthemis aciphylla(2009) Güven, Kıymet; Karabacak, Ersin; Çelik, Sezgin; Uysal, İsmetThe antimicrobial activity of the ethanol, aseton, ethyl asetate and chloroform extracts from Centaurea derderiifolia Wagenitz (Asteraceae) , Stachys aleurites Boiss. (Lamiaceae) and Anthemis aciphylla Boiss. var.aciphylla (Asteraceae) were investigated by agar-well diffusion assay. These extracts were tested in vitro against 26 bacterial and 3 yeast species. Etyhl acetate and acetone extracts of C. derderiifolia, S. aleurites and A. a.var. aciphylla showed antimicrobial activity in varying degrees on all the microorganisms tested. However, chloroform and ethanol extracts of all the plants were not active on some microorganisms tested. Ethyl asetate extracts of the samples exhibited stronger and broader spectrum of antimicrobial activity as compared to ethanol, aseton and chloroform extracts. Therefore, minimal inhibitory concentration (MIC) of only ethyl acetate extracts of the samples was determined for seven bacteria chosen from agar-well diffusion assay. MIC values of the extracts were between 250-125 ?g/ml. In conclusion, ethyl asetate extract of C. derderiifolia was the most active against Aeromonas hydrophila both in agar-well diffusion and MIC assaysÖğe Antimicrobial and Antioxidant Activities of Some Species of Centaurea Collected from Turkey(Asian Journal Of Chemistry, 2013) Uysal, İsmet; Çelik, Sezgin; Sağlam, Hüsniye; Güven, KıymetThe antimicrobial activity of the ethanol, acetone, ethyl acetate and chloroform extracts from Centaurea persica Boiss., C. polyclada DC. and C. consanguinea DC. (Asteraceae) were investigated by agar-well diffusion assay. All of the extracts exhibited an antimicrobial effect against most of the bacteria and all of the yeasts tested. The plant extracts were also screened for radical scavenging potential using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) in vitro model system for antioxidant activity. Ethyl acetate extracts showed the most significant inhibitory activity. Therefore, the minimal inhibitory concentration (MIC) of only ethyl acetate extracts of the samples was determined and C. consanguinea showed the highest antimicrobial effect. However, the ethanol extract of C. polyclada at 0.5 mg/ml, concentration displayed the highest antioxidant activity. This activity was followed by ethanol extracts of. C. persica, ethyl acetate extracts of C. polclada, C. persica and C. consanguinea respectively.