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    Clinical and demographic factors associated with early relapse in patients with schizophrenia: a naturalistic observation study
    (Lippincott Williams & Wilkins, 2021) Gundogmus, Ibrahim; Aydin, Mikail Burak; Oz, Sefa; Tasci, Azize Beril; Uzun, Ozcan
    Schizophrenia is a chronic psychiatric disorder progressing in relapses. Identification of many factors that may potentially increase the risk of relapse will be an important step in preventing relapses. The aim of this study was to determine the rate of early relapse in patients with schizophrenia and possible risk factors related to early relapse. The sample of this prospective study with the naturalistic observation design consisted of 308 patients with schizophrenia. The cutoff value for early relapse was determined as 1 year. The mean age of participants was 37.38 +/- 12.28 years and 66.6% of them were male (n = 205). The early relapse rate was 38.3%. The age younger than 35 [hazard ratio (HR) = 2.313; 95% confidence interval (CI), 1.518-3.526; P < 0.001], use of psychoactive substance (HR = 2.200; 95% CI, 1.407-3.440; P = 0.001), previous attempt of suicide (HR = 1.565; 95% CI, 1.028-2.384; P = 0.037), bad adherence to treatment (HR = 3.102; 95% CI, 1.358-7.086; P = 0.007), long-acting injectables (LAIs) antipsychotics in the treatment (HR = 0.534; 95% CI, 0.351-0.812; P = 0.003), combination typical-atypical antipsychotics (HR = 0.326; 95% CI, 0.131-0.807; P = 0.015), number of episodes (HR = 1.088; 95% CI, 1.043-1.134), and the score on the Side Effect factor of the Clinical Global Impressions Scale (HR = 1.826; 95% CI, 1.357-2.458; P < 0.001) were identified as the independent predictors of early relapse. It is remarkable that treatment bad adherence, use of psychoactive substance, no LAIs antipsychotics included in the treatment, and the no presence of the combination of typical and atypical antipsychotics are alterable predictors of early relapse.
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    Comparison of USG-guided or landmark approach fascia iliaca compartment block for positioning in elderly hip fracture patients with spinal anesthesia: a randomized controlled observational study
    (Tubitak Scientific & Technological Research Council Turkey, 2021) Erturk, Tuna; Gundogmus, Ibrahim; Guner, Temel; Yildirim, Cengiz; Ersoy, Aysin
    Background/aim: Currently, the elderly population in the world is rapidly increasing due to technological developments and convenient access to health services. Due to comorbidities in elderly patients, hip fractures are frequently observed after exposure to environmental trauma. To reduce pain during positioning in spinal anesthesia, fascia iliaca compartment block (FICB) can be applied easily and reliably. In our study, we aimed to compare the analgesic effects and duration of fascia iliaca compartment blocks performed with USG guidance or the landmark approach methods for relieving spinal anesthesia position pain. Materials and methods: Our study included 100 patients undergoing operations due to hip fracture and administered spinal anesthesia after FICB. The group with USG-guided FICB (USG) had the blockage needle advanced to the compartment under the fascia iliaca, and 15 mL bupivacaine + 10 mL 2% lidocaine was administered. They were placed in sitting position for spinal anesthesia 20 min later and procedure duration and numerical rating scale (NRS) scores were recorded. In the group with landmark approach FICB (LAND), the spina iliaca anterior superior (SIAS) and pubic tubercle were connected with a line. The same amount of local anesthetic was administered to the external 1/3 portion of this line with the double pop technique. Procedure duration and NRS scores were recorded. Results: There was no statistically significant difference between the two groups in terms of NRS scores (p: 0.073). There was a statistically significant difference in duration of FICB administration between the two groups (p < 0.001). Conclusion: Both USG-guided and landmark approach FICB methods provide adequate and similar analgesia for positioning in spinal anesthesia. However, in cases where there is no problem with access to the ultrasound device or time, safer blockage can be provided by imaging neurovascular structures with ultrasound.
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    Effects of the EMDR Couple Protocol on Relationship Satisfaction, Depression, and Anxiety Symptoms
    (Springer Publishing Co, 2021) Dogan, Ceren Kurtay; Yasar, Alisan Burak; Gundogmus, Ibrahim
    The aim of the present study was to evaluate the effect of the eye movement desensitization and reprocessing (EMDR) Couple Protocol on the relationship-satisfaction, depression, and anxiety levels of couples. This protocol differs from standard EMDR procedures in that the partners are together in the treatment session, and engage in bidirectional stimulation simultaneously.The treatment targets are disturbing events that the couples have experienced together. Couples have the opportunity to accept, recognize, and witness each other's recovery process during the session.The EMDR Couple Protocol consists of eight phases, and it was developed for couples wanting to improve their relationship. The study sample consisted of 18 couples suitable for the application of the EMDR Couple Protocol. Treatment was provided by an EMDR Europe Level 2 EM DR psychotherapist to the couples. The mean number of sessions was 14.27 +/- 4.04.The couples showed significant improvement between pre-EM DR, post-EMDR, and at three months follow-up with large effect sizes for relationship satisfaction (eta(2) = 0.944), depression (eta(2) = 0.385), and anxiety (eta(2) = 0.258). The present study evaluating the effectiveness of the EMDR Couple Protocol showed a positive effect on the relationship-satisfaction, depression and anxiety symptoms of the couples. The EMDR Couple Protocol appeared to be safe and effective.
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    Evaluation of Intracranial Pressure Change During Electroconvulsive Treatment by Optic Nerve Sheath Diameter
    (Mediafarm Group, 2021) Erturk, Tuna; Gundogmus, Ibrahim; Ersoy, Aysin
    Background: Electroconvulsive therapy (ECT) is an irreplaceable form of treatment used in many psychiatric disorders. However, its effect on the central nervous system is not clearly known. Optic Nerve Sheath Diameter (ONSD) can be measured by ultrasound and has been shown to vary with intracranial pressure. In our study, we aimed to evaluate the intracranial pressure changes that may be caused by ECT with ONSD. Methods: In this study, ONSD measurements of 20 psychiatric patients who underwent ECT were evaluated before and after the ECT session. Results: There was a statistically significant increase in ONSD from that measured after anesthetic administration but before rocuronium administration (baseline) to after the completion of individual ECT treatments, and baseline ONSD also showed a steady increase from the first to the fifth treatment, which reached statistical significance at the fifth treatment. Conclusion: Classically, it was found that ICP increased with ECT. But more importantly if ONSD reflects the ICP realistically; these results showed that ICP tends to increase with each ECT, and this increase significantly differs as the number of sessions progresses.
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    Impact of the first, second and third peak of the COVID-19 pandemic on anxiety, depression and stress symptoms of healthcare workers
    (Aepress Sro, 2022) Gundogmus, Ibrahim; Bolu, Abdullah; Unsal, Cansu; Alma, Leyla; Gundogmus, Pinar Demir; Takmaz, Taha; Okten, Sabri Berkem
    BACKGROUND AND OBJECTIVES: Numerous studies have been conducted on the psychological effects of the COVID-19 pandemic. However, how the mental health of health workers will be affected among the number of peaks during the pandemic has not been evaluated yet. The study aims to investigate the effects of the first, second, and third peaks of COVID-19 on anxiety, depression, and stress symptoms in healthcare workers. METHODS: The current study included 4031 healthcare workers, 1051 during the first peak period, 1409 during the second peak period, and 1571 during the third peak period. The Depression Anxiety Stress scale-21(DASS-21) was used to assess the participants' levels of anxiety, depression, and stress symptoms. RESULTS: The mean age of the participants was 33.74 +/- 7.95, and 2634 (66.3 %) were female. 36.9 %(n = 1486) of the participants were physicians, 41.1 % (n = 1655) were nurses and 22.1 % (n = 890) were other healthcare workers. A statistically significant difference was documented in the DASS-21 anxiety (F(2:4028) = 502.893, p < 0.001, Post-hoc = 3. Peak > 2. Peak > 1. Peak), DASS-21 depression (F(2:4028) = 46.034, p < 0.001, Post-hoc = 3. Peak > 2. Peak > 1. Peak), DASS-21 stress (F(2:4028) = 65.548, p < 0.001, Post-hoc = 3. Peak = 2. Peak > 1. Peak), and DASS-21 total scores (F(2:4028) = 156.860, p < 0.001, Post-hoc = 3. Peak > 2. Peak > 1. Peak) of healthcare workers during all three peak periods. CONCLUSIONS: Our findings show that as the peak number rises, so do the levels of anxiety and depression among healthcare workers. As a result, it is possible to assert that prolongation of the COVID-19 pandemic worsens mental problems (Tab. 2, Fig. 3, Ref. 35). Text in PDF www.elis.sk