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Öğe Clinical aspects of blood transfusion in cats(Ankara Univ Press, 2009) Arikan, Sevket; Gurkan, MehmetThe safe use of transfusion therapy requires proper knowledge on blood groups, blood typing, donor selection, blood collection, transfusion protocols and adverse transfusion reactions. Type B cats have high titres of naturally occurring anti-A isoagglutinins and type A cats have generally low titred anti-B isoagglutinins in their plasma. The severity of incompatibility reactions in blood transfusion is proportional to the alloantibody titres of the recipient blood. Transfusion of type B blood to type A cats may develop a mild transfusion reactions. In contrast, administration of type A blood to type B cats can cause potentially fatal acute hemolytic transfusion reactions. Adverse transfusion reactions can be avoided by typing donor and recipient cats before transfusion and by administering only matched blood. Due to improvement in feline blood typing, collecting and administration procedures, there has been a notable increase in the blood transfusion therapy in these animals. Present paper reviews current understanding of the pactical aspects of transfusion therapy in cats.Öğe Comparison of the Efficacy of Gutta-percha and Thermafil in Endodontic Treatment in Dogs(Academic Journals Inc, 2011) Pekcan, Zeynep; Kurum, Baris; Gurkan, Mehmet; Kumandas, Ali; Karsli, Birkan; Elma, ErtugrulEndodontic treatment is performed to save periodontally intact teeth with pulpal inflammation, infection or necrosis. There are some endodontic filling materials used in dogs. The aim of this study was to evaluate the clinical application of two different root canal treatments with thermafil and gutta-percha, in dogs. Nineteen tooth roots were treated in 11 dogs. The treated teeth comprised of six first incisors, five second incisors, three third incisors and five canine teeth. Root canal treatment was decided to be performed after clinical and radiological examination. The depth of the gingival sulcus, dental mobility, haemorrhage after probing and change of tooth colour were assessed and periapical lesions and root resorption were evaluated after dental radiographic examination. In clinical examination, exposed dental pulp, dental mobility, discoloration and fracture were recorded in 14, 3, 6 and 4 teeth, respectively. Periapical lesions were recorded in 4 teeth and root resorption was determined in 2 teeth during dental radiological examination. The root canal was filled with gutta-percha in 12 tooth roots and with thermafil in 7 tooth roots. Afterwards, access openings were closed with a composite resin. Of the 12 tooth roots obturated with gutta-percha, 4 were filled with 55 mm long-gutta-percha plugs manufactured specifically for carnivores and the others were obturated with commercially available 25 mm-long gutta-percha plugs. Both techniques were observed to be applicable; however, obturation with thermafil proved to be much easier. As regards the time needed for application, thermafil was applied within shorter periods compared to gutta-percha. However, the results obtained showed that, instead of using gutta-percha cones and a file of the same size, it would be better to prefer a smaller size thermafil cone to obturate the full length of the root canal.Öğe Effects of Halothane and Isoflurane Anaesthesia on Antioxidant Enzymes in Dogs(Medwell Online, 2010) Yarsan, Ender; Gurkan, Mehmet; Pekcan, Zeynep; Ince, Sinan; Kumandas, AliFree radicals, along with the impairment of biological membranes and cellular structures and increased biological activity, come out with the results of the changes in the activity of the enzymes followed by the damages of cellular function and metabolism This condition was attributed to the initiation effects of anaeshetics and other drugs which are used throughout the general anaesthesia General anaesthesia which is constructed with using many drugs which have various physicochemical structures is a condition affecting lipid peroxidation in the organism directly or indirectly In the frame of the study, the effects of halothane and isoflurane used in the anaesthesia on Malonyldialdehyde (MDA) concentration were investigated The study was carried out on 14 dogs with various breeds, ages and sexes which were admitted to Kirikkale University, Faculty of Veterinary Medicine and with various signs of complaint and determined as healthy according to the clinical and haemotological examination In the experiment, halothane (1-2 5%) and isoflurane (1-3%) were investigated as the anaesthetic substances Diazepam (0 3 mg kg(-1), IM) was administered as preanesthesia and thiopenthal sodium (10 mg kg(-1), IV) was administered for the induction of anesthesia to dogs Halothane and isoflurane were administered to the dogs in the first and second group, respectively The duration of anaesthesia was determined as 60 mm Five blood samples were taken from the animals at the time prior to premedication, immediately before the gas anaesthesia, after 1 h of the initiation of anaesthesia, 3 and 24 h after the end of anaesthesia into the heparinated tubes Malonyldialdehyde levels were measured in plasma During the experimental period, body temperatures, heart rate, respiration rate and blood oxygen saturation values were recorded Malondialdehyde levels measured during the halothane anaesthesia were numerically lower than those determined in isoflurane anaesthesia in same time period However, they reached the same levels prior to the anaesthesia within 24 h m both groups The differences between the two groups were statistically insignificant (p>0 05) Additionally, there were no significant differences in body temperature, heart rate, respiration rate and blood oxygen saturation values between the anaesthethic drugs Results of the comparisons of time and drug type showed that anaesthesia procedures using both halothane and isoflurane did not have any negative effect on the oxidative metabolism in dogs
