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    Postobturation Pain of three Novel Calcium Silicate-based sealers with asymptomatic irreversible pulpitis or necrotic pulp with chronic apical periodontitis: prospective clinical trial
    (Bmc, 2024) Turkyilmaz, Ali; Baris, Sevda Durust; Hancerliogullari, Dilek; Erdemir, Ali
    Background Bioceramic-based root canal sealers are increasingly important in root canal treatment because of their biocompatible properties. This study aimed to evaluate postobturation pain incidence and intensity after root canal obturation with NeoSealer Flo, MTA-Bioseal, and GuttaFlow bioseal calcium silicate-based sealers and AH Plus epoxy resin-based sealer in patients with asymptomatic irreversible pulpitis or necrotic pulp with chronic apical periodontitis. Methods A total of 120 participants with single-rooted teeth were included and randomly divided into four groups according to the root canal sealer used (n = 30). The patients were subsequently categorised based on the pulp vitality (vital or nonvital) in each group (n = 15) and all teeth were obturated in a single-visit. The postobturation pain scores were recorded on a visual analogue scale (VAS) at 6 h, 24 h, 48 h, 72 h, 7 d and 30 d. Moreover, analgesic intake was also noted at 24 h and 48 h. The Mann-Whitney U test, Kruskal-Wallis H test, Friedman test, and Spearman's correlation test were used, and a p value < 0.05 was considered significant. Results VAS scores were highest for the 6 h > 24 h > 48 h approximate to 72 h approximate to 7 d approximate to 30 d time intervals for both pulp status in each root canal sealer. A significant decrease in the VAS score was observed for all sealers from 6 h to 48 h (p 0.05). Nonvital cases had lower VAS scores at all time intervals. Analgesic intake was greater in the first 24 h (p < 0.05) in vital cases (p < 0.05) and also in females than males. Conclusion The level of pain experienced after obturation was similar in patients with different pulp status for all the root canal sealers. Analgesic intake was greater in vital cases and females within 24 h.
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    Quality of information in #brokenfileremoval Reels videos on Instagram: a cross-sectional study
    (Springer Heidelberg, 2023) Hancerliogullari, Dilek; Ceylanoglu, Eray
    Aim Instagram is a popular social media platform for sharing videos and photos that is widely used by individuals worldwide. The objective of this study was to assess the information quality of Reels videos on Instagram with respect to broken files, a complication in endodontic treatment.Subject and methods Reels videos were searched on May 16 between 19:00 and 23:00 using English hashtags (#brokenfile, #brokenfileremoval, #brokeninstrument, #brokeninstrumentremoval). The videos related to the subject were examined based on their characteristics and uploaders. The videos were evaluated by Global Quality Scale (GQS) scores, modified DISCERN, and JAMA criteria. Descriptive statistics were obtained, and the data were analyzed with the Kruskal-Wallis and Spearman rho tests.Results Of the 205 downloaded Reels videos, 54 met the criteria for analysis. Most posts were posted by specialists (79.62%, n = 43), hospitals/universities/clinics (9.25%, n = 5), health-related businesses (5.55%, n = 3), and others (5.55%, n = 3). The GQS (1.50 +/- 0.66), modified DISCERN score (1.57 +/- 0.68), and JAMA criteria (1.85 +/- 0.41) of Instagram video posts about #brokenfileremoval were found to be very low. A strong positive correlation was found between the number of followers and viewing rates (p < 0.001).Conclusion The Reels videos related to #brokenfile #brokenfileremoval, #brokeninstrument, and #brokeninstrumentremoval were limited in number and of low quality. Therefore, specialists should upload more comprehensive videos to effectively utilize this platform.
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    The effect of different irrigation solutions and activation techniques on the expression of growth factors from dentine of extracted premolar teeth
    (Wiley, 2021) Hancerliogullari, Dilek; Erdemir, Ali; Kisa, Ucler
    Aim To evaluate in a laboratory study, the effect of different canal irrigant solutions and activation techniques on transforming growth factor (TGF-beta 1), insulin growth factor-1 (IGF-1), bone morphogenetic protein-7 (BMP-7) and vascular endothelial growth factor-A (VEGF-A) release levels from the dentine of extracted premolar teeth. Methodology Seventy premolar teeth with single root and canal were used. The lengths of the root segments were standardized to 12 mm, and the root canals were prepared up to size 100 with hand files. All surfaces of the teeth were covered with nail polish except the inner root canal surface. The root canals were irrigated with 1.5% NaOCl. Ten teeth were allocated to the control group. The remaining sixty teeth were divided into 2 main groups according to the chelating agent used (17% EDTA, 10% Citric acid; CA) and 3 subgroups (n = 10) according to irrigation activation technique (conventional syringe irrigation (CSI), passive ultrasonic irrigation (PUI) and Er:YAG laser activation). After the activation procedure, the root segments were placed into eppendorf tubes containing 1 mL of phosphate-buffered saline solution and kept at 37celcius. TGF-beta 1, IGF-1, BMP-7 and VEGF-A release levels from dentine were measured using the enzyme-linked immunosorbent assay (ELISA) method at 24 h and at day 7. The volume of root canals was calculated using cone-beam computed tomography. The growth factor levels were calculated in ng/mL except VEGF-A (pg/ml). Normality analysis of the data was evaluated with the Kolmogorov-Smirnov test. Statistical analysis was performed using the Mann-Whitney-U and Wilcoxon tests. Results Regardless of the activation type and sampling time, EDTA caused significantly more IGF release than did CA, whereas EDTA and CA were equally effective for the release of the other growth factors. For either EDTA or CA, the lowest and highest growth factor release levels were observed in the CSI and Er:YAG laser groups, respectively (p < .05). All of the growth factors were released significantly more at 24 h than on day 7 (p < .05). Conclusions Irrigation activation techniques with EDTA or CA increased the release levels of all growth factors from the dentine of canal walls in extracted premolar teeth.