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    Comparison of American and European Guidelines for the Management of Patients With Valvular Heart Disease
    (Elsevier Inc, 2023) Inanc, Ibrahim Halil; Cilingiroglu, Mehmet; Iliescu, Cezar; NInios, Vlasis; Matar, Fadi; Ates, Ismail; Toutouzas, Konstantinos
    This review compares the recommendations of the recent 2020 American College of Cardiology (ACC)/American Heart Association (AHA) and 2021 European Society of Cardiology (ESC)/European Association for CardioThoracic Surgery (EACTS) guidelines on the management of patients with valvular heart disease (VHD). ACC/ AHA and ESC/EACTS guidelines are both the updated versions of previous 2017 documents. Both guidelines fundamentally agree on the extended indications of percutaneous valve interventions, the optimal use of imaging modalities other than 2D echocardiography, the importance of a multidisciplinary Heart Team as well as active patient participation in clinical decision making, more widespread use of NOACs and earlier intervention with lower left ventricular dilatation thresholds to decrease long-term mortality. The differences between the guidelines are mainly related to the classification of the severity of valve pathologies and frequency of follow-up, level of recommendations of valve intervention indications in special patient groups such as frail patients and the left ventricular diameter and ejection fraction thresholds for intervention. (c) 2022 Elsevier Inc. All rights reserved.
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    Effectiveness and Safety of Same-Day Discharge After Left Atrial Appendage Closure Using Moderate Conscious Sedation: One-Year Follow-Up Outcomes
    (Elsevier Science Inc, 2023) Inanc, Ibrahim Halil; Mutlu, Deniz; Marmagkiolis, Kostas; Iliescu, Cezar; Ates, Ismail; Feldman, Marc; Cilingiroglu, Mehmet
    [Abstract No tAvailable]
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    Feasibility of Same-Day Discharge Approach After Transcatheter Mitral Valve Repair Procedures: One-Year Follow-Up Outcomes
    (Elsevier Science Inc, 2023) Inanc, Ibrahim Halil; Mutlu, Deniz; Marmagkiolis, Kostas; Iliescu, Cezar; Ates, Ismail; Feldman, Marc; Cilingiroglu, Mehmet
    [Abstract No tAvailable]
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    Use of IVOCT for Assessment of the Lesion Characteristics as Well as Evaluation of Vascular Healing Effects of Different Technologies in PAD Patients
    (Elsevier Science Inc, 2023) Inanc, Ibrahim Halil; Mutlu, Deniz; Marmagkiolis, Kostas; Iliescu, Cezar; Ates, Ismail; Feldman, Marc; Cilingiroglu, Mehmet
    [Abstract No tAvailable]
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    Use of SAFARI 2 as Workhorse Wire for Left-Sided Structural Heart Interventions
    (Elsevier Science Inc, 2023) Inanc, Ibrahim Halil; Mutlu, Deniz; Rollefson, William; Marmagkiolis, Kostas; Iliescu, Cezar; Ates, Ismail; Feldman, Marc
    [Abstract No tAvailable]
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    Use of SAFARI 2n° as workhorse wire for left-sided structural heart interventions
    (Elsevier Inc, 2024) Inanc, Ibrahim H.; Mutlu, Deniz; Marmagkiolis, Kostas; Iliescu, Cezar; Ates, Ismail; Cilingiroglu, Mehmet
    Background: With the advances in percutaneous treatment technologies, the left atrial appendage occlusion (LAAO) and the transcatheter mitral valve repair using MitraClip (TMVR) are increasingly being performed today. The SAFARI 2n degrees guidewire is primarily used during transcatheter aortic valve implantation (TAVI), our group has also been using it during MitraClip and LAAO procedures. Our clinical study aimed to share our data on the safety and effectiveness for the use of the SAFARI 2n degrees guidewire during MitraClip or LAAO procedures. Methods: This study included a total of 1730 patients (948 patients of MitraClip and 782 of LAAO). It was designed as single arm, retrospective, and multicenter between July 2016 and August 2022. SAFARI 2n degrees guidewire was used exclusively during all the procedures. Results: A total of 1730 patients (male 55.8 %) were included in the study. There was no guidewire-related complications, stroke/transient ischemic attack, bleeding (minor/major/life-threatening), need for cardiac surgery, pneumonia, and vascular dissection/rupture in patients undergoing LAAO. There were 2 device-related pericardial effusions without tamponade. No stroke/transient ischemic attack, bleeding (minor/major/life-threatening), mortality, need for cardiac surgery, pneumonia, guidewire-related complication, pericardial effusion, vascular dissection/rupture, or clip embolization was observed in patients undergoing MitraClip. Conclusions: By taking advantage of its pre-shaped structure, the SAFARI 2n degrees guidewire seems to offer a reliable and safe device delivery for both MitraClip and LAAO procedures as a regular work horse wire. Our results should be confirmed by larger randomized or prospective trials.