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Öğe Bilateral Optic Neuritis After Influenza Vaccination(Informa Healthcare, 2010) Tan, Funda Uysal; Akarsu, Cengiz; Gullu, Reyhan; Kansu, TulayOptic neuritis is a rare complication of vaccination. We report a 55-year-old woman who presented with bilateral optic neuritis following influenza vaccination. The patient has typical features of acute optic neuritis with acute visual loss, periocular pain, visual defects, full recovery of vision after 6 months, and the absence of deterioration after withdrawal of corticosteroids. Considering the absence of oligoclonal bands in the cerebrospinal fluid analysis and the nonexistence of lesions resembling multiple sclerosis (MS) in cranial magnetic resonance imaging, the case at present does not appear to be associated with MS.Öğe Post-thymectomy, seronegative myasthenia gravis(Taylor & Francis Inc, 2008) Tan, Funda Uysal; Kansu, Tulay; Akarsu, CengizPatients with thymoma associated myasthenia gravis (MG) usually present with severe disease unresponsive to usual treatment and almost all have antibodies against acetylcholine receptors (AChR). We like to present a case of post-thymectomy, seronegative MG. A 55-year-old man was referred with horizontal diplopia and abduction deficit in the right eye two years after he had thymectomy for a thymoma. Single-fiber electromyography was diagnostic for MG and AChR titer was undetectable. Ocular signs did not response to pyridostigmine, prednisolone and immunoglobulin treatments and the patient also suffered from proximal weakness and pain in the extremities. Cyclosporine-A was started and the initial response was favorable with a decrease in general weakness.