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    Sigmoid Colon Perforation Mimics a Tuboovarian Absces
    (2018) Sayan C.D.; Yeral M.I.; Ozkan Z.S.; Karaca G.; Asal N.; Aydın O.; Sagsoz N.
    Introduction: An adnexal mass may be diagnosed after a routine pelvic ultrasonographic examination or an emergent hospital admission due to rupture of ectopic pregnancy, adnexal torsion or rupture of tuboovarian abscess. It is necessary to evaluate the origin of the mass initially and to classify patients who need further evaluation and treatment for an urgent condition.Case presentation: We report a case of sigmoid colon rupture due to sigmoid colon adenocarcinoma presenting as acute abdomen with left adnexal mass in a 28 years old woman. Abdominopelvic computed tomography revealed a left adnexal mass with suspicion of tuboovarian abscess. In laparatomy, rupture of sigmoid colon was observed and resection of sigmoid colon was performed. Histological examination of resection part revealed diagnosis of sigmoid colon adenocarcinoma due to familial adenomatous polyposis.Conclusion: This case may be interesting for clinicians because pelvic pain, fever, increased infection markers in the laboratory and mass at ultrasonography or other screening methods could cause a misdiagnosis of tubaovarian abscess especially in reproductive age women. Before the operation of the pelvic mass of all age women with the diagnosis of tuboovarian abscess other causes of the pelvic abscess should come into mine and necessary preparation for operation must be done.
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    Transversus abdominis plane (TAP) block for postoperative analgesia after laparoscopic cholecystectomy, a retrospective study
    (Anestezi Dergisi, 2019) Yaman F.; Karaca G.; Colak S.; Ates G.; Pehlivanlı F.; Gencay I.; Aydın G.
    Objective: Laparoscopic cholecystectomy is a minimally invasive surgical procedure but it is still associated with postoperative pain within the first 24 hours. Ultrasound-guided transversus abdominis plane block is a regional anesthetic technique which provides postoperative analgesia in abdominal surgery. We aimed to determine the effects of the TAP block on discharge time, non-opioid and opioid consumption, shoulder tip pain, incidence of postoperative nausea and vomiting, and severity of pain evaluated with visual analogue scale in patients who underwent laparoscopic cholecystectomy. Methods: Seventy-two eligible patients who underwent laparoscopic cholecystectomy were included in the study. In 38 patients ultrasound-guided TAP block was performed, and 34 patients were treated with conventional methods such as non-steroid anti-inflamatory drugs. Data related to VAS pain scores, shoulder tip pain, intraoperative opioid consumption, postoperative non-opioid and opioid consumption, nausea vomiting and discharge time were collected retrospectively to determine statistically significant differences between TAP block and non-TAP block groups. Results: VAS pain scores were globally reduced at all time periods in two groups (significant group main effect, F(7.760)=94.47, P<0.001). VAS pain scores were significantly lower at all measurement intervals except 24h in the TAP group than in the non-TAP group. Shoulder pain was significantly higher in TAP block group than non-TAP block group (p<0.001). Any statistically significant difference was not found between the groups in terms of intraoperative, and postoperative opioid consumption, discharge time, nausea and vomiting. Conclusion: Ultrasound-guided TAP block is an effective regional analgesic technique to decrease postoperative abdominal pain, however TAP block does not reduce shoulder tip pain. Multimodal pain management is required after laparoscopic cholecystectomy. © Copyright Anesthesiology and Reanimation Specialists' Society.
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    What is the protective effect of krill oil on rat ovary against ischemia–reperfusion injury?
    (Blackwell Publishing, 2019) Yeral I.; Sayan C.D.; Karaca G.; Simsek Y.; Sagsoz N.; Ozkan Z.S.; Atasoy P.
    Aim: In this study, we aimed to investigate the protective effect of krill oil (KO) against ischemia–reperfusion (I/R) injury on rat ovary. Methods: This study was conducted with 32 Wistar Albino rats. Rats were divided into four groups, with eight rats in each group-as follows: Sham group, I/R group, I/R + low dose KO group (50 mg) and I/R + high dose KO group (500 mg). The histopathological and follicle counts were performed on the right ovary. The total antioxidant status, total oxidant status and oxidative stress index were evaluated on the left ovary. And also serum N-thiol level, serum T-thiol level, serum disulfide (SDS) level, serum disulfide/N-thiol and serum disulfide/T-thiol ratios were evaluated too. Results: A statistically significant difference was determined between the I/R group and all the other groups for all parameters. There was significant difference between KO groups and the Sham group for the parameters of serum N-thiol, serum T-thiol, SDS, serum disulfide/N-thiol and serum disulfide/T-thiol. SDS, total oxidant status and oxidative stress index were determined to be the highest in the I/R group and the lowest in the low dose KO group. The total antioxidant status values were found to be the highest in the high dose KO group and the lowest in the I/R group. Follicle counts and histological injury scores showed no significant difference between Sham and KO groups. Conclusion: This study demonstrated that KO has beneficial effects on decreasing the injury after I/R on rat ovary. © 2018 Japan Society of Obstetrics and Gynecology