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    Mediatory effect of alexythymiaon the relationship between cyberchondria and somatosensory amplification in psoriasis patients
    (Cukurova Univ, Fac Medicine, 2024) Kalaycı, Bülent Nuri; Kartal, Fatma; Salcan, Tarık; Mete, Burak
    Purpose:We hypothesized that the level of cyberchondriamay be related to exaggeration of bodily sensations in patients diagnosed with psoriasis and that the level of alexithymia may have a mediating effect on this relationship.Materials and Methods:Our research sample consists of 101 patients diagnosed withPsoriasis and 89 healthy controls. Psoriasis Area and Severity Index (PASI) was applied to patients diagnosed with psoriasis. All participants completed the Sociodemographic Data Form, Cyberchondria Severity Scale (CCS), Toronto Alexithymia Scale (TAS), Beck Depression Inventory (BDI), Beck AnxietyInventory (BAI) and Somatosensory Amplification Scale (SSAS).Results:SC & Ouml; F1, F2 subscale and total scores in the control group; f5 scores were statistically significantly higher in the psoriasis group. SSAS total scores in the psoriasis group were statistically significantly higher than in the control group.A significant, positive and low level correlation was found between PASI and SCS f1, BD and ssas scores in psoriasis patients. There is a significant, positive and significant difference between PASI and BA scores. A moderate correlation was found. The mediating effect of alexithymia in the relationship between cyberchondria and exaggeration of bodily sensations. In the mediation analysis examined, alexithymia was found to be a partial mediator. Both the direct and indirect (mediating effect) effects of cyberchondria on alexithymia are significant.Conclusion:Alexithymia has a mediating effect on the relationship between cyberchondria and exaggeration of bodily sensations in patients with psoriasis. In clinica practice, assessing the level of exaggeration of bodily sensations and alexithymia may be predictive to determine the pathological level of health information seeking behavior in people suffering from chronic diseases such as psoriasis.
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    Parietal Cortex Volume and Functions in Major Depression and Bipolar Disorder: A Cloud-Based Magnetic Resonans Imaging Study
    (Turkish Neuropsychiatry Assoc-Turk Noropsikiyatri Dernegi, 2024) Kılıç, Fatma; Kartal, Fatma; Erbay, Mehmet Fatih; Karlıdağ, Rıfat
    Introduction: The present study aimed to compare the Parietal Lobe (PL) volumes and Cancellation Test (CT) performances of euthymic patients with Bipolar Disorder -1 (BD) and Major Depressive Disorder (MDD), and healthy controls. Methods: The present study included 63 participants in three groups; two patient groups in remission involving patients with BD and MDD diagnosed according to DSM-5 and a control group with healthy individuals. Sociodemographic Data Form, CT, and Hand Preference Questionnaire were applied to all participants. Participant PL volumes were measured with the Cloud-Based Brain Magnetic Resonance Image Segmentation - Parcellation System. Results: Both patient groups exhibited lower PL volume when compared to the control group, and there was no difference between the patient groups based on PL volume. It was determined that MDD and BB patients scored less in the CT when compared to the control group. There was a weak correlation between right and left PL volumes and CT performances. Conclusion: The present study findings demonstrated that BD and MDD patients in remission exhibited lower PL volume and CT performance when compared to healthy controls, emphasizing that PL could be structurally and functionally significant in the pathophysiology of mood disorders.