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  • Küçük Resim
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    Effect of Locally Applied bFGF on Implant Stability: Biomechanical Evaluation of 2 Different Implant Surfaces in Rabbits
    (Lippincott Williams & Wilkins, 2014) Kartal, Yasemin; Ucok, Cahit; Ozgul, Ozkan; Kocyigit, Ismail Doruk; Suer, Berkay Tolga
    Objectives: The aim of this study was to evaluate the implant stability with the addition of local application of basic fibroblast growth factor (bFGF) during the osseointegration of 2 different dental implant surfaces using rabbit tibia model. Materials and Methods: Fifty-six dental implants, 28 of hydrophilic surface (SLActive) and 28 of hydrophobic surface (OsseoSpeed), were placed in 14 mature New Zealand rabbits. The rabbits each received both SLActive and OsseoSpeed implants per tibia, and bFGF was applied locally on 1 randomly selected tibia. Half of the subjects were killed at the fourth week of healing period, and the other half were killed at the twelfth week. Stabilization was assessed using resonance frequency analysis (RFA) and removal torque value (RTV). Results: The local application of bFGF was found to enhance osseointegration, especially at the fourth week of healing period after application (P = 0.046). RFAs and RTVs were found to be higher in bFGF-treated implant with hydrophilic surfaces when compared with both bFGF-treated hydrophobic implants and nontreated hydrophilic controls. Conclusion: Local application of bFGF seems to increase the stabilization values in implants with hydrophilic surfaces and those with hydrophobic surfaces.
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    Evaluation of Preoperative Model Surgery and the Use of a Maxillary Sinus Surgical Template in Sinus Floor Augmentation Surgery
    (Lippincott Williams & Wilkins, 2013) Kocyigit, Ismail Doruk; Coskunses, Fatih Mehmet; Ozgul, Ozkan; Tuz, Hakan Hifzi; Kartal, Yasemin; Polat, Muhlis; Orhan, Kaan
    Maxillary sinus augmentation is an accepted technique for dental implant placement in presence of insufficient maxillary bone. There are various techniques in the literature, either by crestal or lateral approach in maxillary sinus augmentation that have high percentage of success, while all have complications. Schneiderian membrane perforation is the most common complication encountered during surgery. The aim of this study was to evaluate the benefits of preoperative model surgery and the ease of use of a maxillary sinus surgical template (MSST) during maxillary sinus augmentation surgery with a lateral approach. Ten patients included in the study needed rehabilitation of a partially or totally edentulous maxilla with an implant-supported fixed prosthesis and requiring sinus augmentation. A questionnaire was asked to performing surgeons, and study results showed the use of an MSST was found to be effective in terms of adaptation (62.5%), window preparation (87.5%), ease of elevation (95.9%), ease of grafting (95.9%), reduction of perforation risk (91.7%), and achieving immobility during the procedure (62.5%); however, the use of an MSST was also found to prolong the surgical procedure (100%) and restrict the view of the surgical area (79.2%). Maxillary sinus augmentation appears to be a useful tool for locating an appropriate entrance to the sinus cavity, allowing for safe elevation of the sinus membrane and effectively grafting the sinus floor.
  • Küçük Resim
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    İkinci nesil trombosit konsantrasyonunun klinik uygulamaları
    (2012) Koçyiğit, İsmail Doruk; Tunalı, Mustafa; Özdemir, Hakan; Kartal, Yasemin; Süer, Berkay Tolga
    Trombositten zengin otoj en ürünlerin tedavi amacı ile kullanılması, güncel bir yaklaşım olarak dikkati çekmektedir. Sert ve yumuşak doku iyileşmelerinde kullanılan ve çok çeşitli büyüme faktörleri ve proteinlerin kontrollü salınımlarını içeren bu preparatların doğal yara iyileşmesi için gerekli olan maddeleri yoğun olarak içerdikleri bilinmektedir. Platelet-rich fibrin (PRF), yeni jenerasyon trombositten zengin otojen ürün olarak bilinmektedir. Kolay uygulanabilir ve biyokimyasal herhangi bir işlem gerektirmeyen PRF protokolü, kişinin kendisinden alınan kan örneklerinden lökositten ve trombositten zengin bir otolog biyomateryal elde edilmesine izin vermektedir. Diş Hekimliğinde özellikle Periodontoloji ve Ağız, Diş ve Çene Cerrahisi’ndeki klinik uygulamalarda kullanılmaya başlanan PRF’nin önemi giderek artmaktadır.