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Öğe Afebrile convulsion in an adult after recombinant hepatitis B vaccination(Taylor & Francis As, 2002) Kaygusuz, S.; Erdemoglu, A.K.; Koksal, I.Vaccination against HBV is important in order to reduce the incidence of HBV infection. Although the HBV vaccine is among the safest of all vaccines, vaccination against HBV has been associated with side-effects. Herein we present a case of afebrile convulsion after recombinant HBV vaccination.Öğe Candida colonisation within a silicone tissue expander(Churchill Livingstone, 2002) Saray, A.; Kaygusuz, S.; Kisa, Ü.; Kilic, D.The fungal contamination of tissue expanders is rarely reported. There are, however, occasional reports of fungi in association with inflatable mammary implants. We describe the colonisation of a tissue expander with Candida albicans, resulting in the fluid becoming a turbid brown colour. The possible modes of inoculation and survival of the microorganism within the expander shell were investigated by means of biochemical and microbiological analyses of the fluid. The colonisation of silicone implants by opportunistic fungi is probably more common than has been reported, and precautions that can be taken to avoid this complication are emphasised. (C) 2002 The British Association of Plastic Surgeons.Öğe CT features of pulmonary embolism in patients with COVID-19 pneumonia(Verduci Publisher, 2023) Ekici, M.; Ekici, A.; Kaygusuz, S.; Inanc, F.OBJECTIVE: The aim of this study was to describe the Computed Tomogra-phy (CT) features of pulmonary embolism in pa-tients hospitalized for acute COVID-19 pneumo-nia and to evaluate the prognostic significance of these features.PATIENTS AND METHODS: This retrospec-tive study included 110 consecutive patients who were hospitalized for acute COVID-19 pneumonia and underwent pulmonary com-puted tomography angiography (BTPA) on the basis of clinical suspicion. The diagnosis of COVID-19 infection was determined by CT find-ings typical of COVID-19 pneumonia and/or a positive result of a reverse transcriptase-poly-merase chain reaction test.RESULTS: Of the 110 patients, 30 (27.3%) had acute pulmonary embolism and 71 (64.5%) had CT features of chronic pulmonary embolism. Of the 14 (12.7%) patients who died despite receiv-ing therapeutic doses of heparin, 13 (92.9%) had CT features of chronic pulmonary embolism and 1 (7.1%) of acute pulmonary embolism. CT features of chronic pulmonary embolism were more com-mon in deceased patients than in surviving pa-tients (92.9% vs. 60.4%, p=0.01, respectively). Low oxygen saturation and high urine microalbumin creatinine ratio at admission in COVID-19 patients are important determinants of mortality after ad-justing for sex and age in logistic procedures.CONCLUSIONS: CT features of chronic pul-monary embolism are common in COVID-19 pa-tients undergoing Computed Tomography Pul-monary Angiography (CTPA) in the hospital. The coexistence of albuminuria, low oxygen satura-tion and CT features of chronic pulmonary em-bolism at admission in COVID-19 patients may herald fatal outcomes.Öğe Efficacy of povidone-iodine in preputial antisepsis(Blackwell Publishing Ltd, 2003) Çakmak, M.; Çaglayan, F.; Kılıç, D.; Kaygusuz, S.; Çakmak, A.; Ulusoy, S.; Osluk, N.Wound infection after a surgical procedure is one of the main problems affecting the success of an operation. The prepuce is used in hypospadias surgery and in tissue defects in reconstructive surgery. The objective of this study is to determine the efficacy of povidone-iodine and surgical soap in preputial skin preparation. Ninety-four healthy children were divided into three groups. After obtaining preputial skin swabs, an application of povidone-iodine 10% was made and skin swabs were obtained after two and five minutes in group 1. An additional application of povidone-iodine after two minutes was made in group 2 and swabs taken. Group 3 received a local scrub with surgical soap and an application of povidone-iodine. Results showed that, despite painting with povidone-iodine and/or local cleaning with surgical soap, it is not possible totally to eradicate the micro-organisms in the prepuce. Surgical soap decreases the colony count, which can lead to increased effectiveness of povidone-iodine after painting. We recommend preoperative local cleaning with surgical soap before surgical painting.Öğe Neopterin levels in nonreplicative HBV carriers(Elsevier Sci Ireland Ltd, 2002) Kilic, D.; Boyunaga, H.; Kaygusuz, S.; Akgul, E.O.; Al Rashed, M.; Kenar, L.; Kutluay, T.The aim of this study was to determine the existence of immune activation by measuring neopterin in HBV (Hepatitis B virus) carriers with viral load (HBV DNA) less than 5 pg/ml. Forty-three subjects and 56 healthy controls were included in the study. Neopterin levels of were compared. ALT and ALP levels in one patient and AST levels in two patients were found minimally higher than upper limit, and GGT levels were within the reference range in all patients. Neopterin levels in the patient group and in the controls were 159.97 +/- 13.39 and 84.10 +/- 11.45 nmol/l, respectively (P < 0.0001). The difference between the two groups was statistically significant (P < 0.0001). In conclusion, the increased neopterin levels of HBV carriers might be the indicators of the effect of cellular immunity. This increase might also implicate a background inflammation based on mainly cellular immunity that exists within the liver. (C) 2002 Elsevier Science B.V. All rights reserved.Öğe Seroprevalence of tetanus immunity among noninsulin-dependent diabetes mellitus patients(Elsevier Science Inc, 2003) Kilic, D.; Kaygusuz, S.; Saygun, M.; Cakman, A.; Uzer, H.; Doganci, L.Tetanus is a preventable disease that continues to affect people in both developing and developed countries. The aim of the present study was to evaluate the immunity profile to tetanus in patients with Type II diabetes mellitus (DM) and to compare them with healthy controls. The tetanus antitoxin levels in 310 diabetic patients (104 males and 206 females) and in 200 healthy controls (72 males and 128 females) were measured by ELISA (Virotech, Germany). The mean antitoxin concentration in patient and control groups were 0.8238+/-1.61 and 0.9978+/-1.49 IU/ml, respectively. There was a statistically significant difference between the two groups (z = -3.520, P = .0001 and odds ratio was 2.367). There was a definitive inverse correlation between the duration of diabetes and tetanus antibody titers (Spearman's correlation analysis, r = -.155, P = .006). A gender-dependent difference in the susceptibility to tetanus was present in the diabetic group with antibody titers being significantly higher in males compared with females (z = -2.267, P = .023). For both of control (chi(2) = 20.207, P = .003) and patient (chi(2) = 43.532, P = .0001) groups, there was a significant inverse correlation between the tetanus immunity levels and age. Statistically, a significant drop in antibody titers of both groups was found as the period past from the last immunization increased (Pearson correlation analysis: for patient group r = -.364, P = .0001; for control group r = -.143, P = .044). The tetanus antitoxin levels were significantly increased in individuals who had primary immunization during childhood (for patient group chi(2) = 17.191, P = .0001; for control group chi(2) = 9.911, P = .007). A significant reduction in the level of antitoxin immunity to tetanus in association with an increased susceptibility to infections in patients with diabetes may implicate the need for improving vaccination rates in this patient group. (C) 2003 Elsevier Inc. All rights reserved.
