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Öğe Platelet-rich fibrin and its use in dentistry(2022) Khaled, Sarah; Olgun, Ebru; Hendek, MeltemPRF is often defined as an autogenous fibrin biomaterial rich in leukocytes and platelets and is clinically easy to obtain and use. Various methods are available to prepare platelet concentrates, albeit the contents of platelet concentrates obtained by different methods also vary. Accordingly, they are divided into P-PRF, L-PRF, i-PRF, A-PRF, and A-PRF+, considering the thrombocyte leukocyte concentrates and fibrin contents. PRF is widely adopted in dentistry as promoting angiogenesis, immunity, and epithelial proliferation.