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    Histomorphometric evaluation of delayed changes in masseter muscle after lengthening the rabbit mandible by distraction osteogenesis
    (Wiley, 2009) Tüz, Hakan H.; Dolanmaz, Doğan; Pampu, A. Alper; Kişnişçi, Reha S.; Günhan, O.
    The aim of the study was to evaluate the delayed responses and changes of gradually lengthened masseter muscles of rabbit mandibles. Unilateral lengthening of rabbit mandibles was performed in 18 New Zealand rabbits for 7 days at the rate of 1 mm day(-1). Mandibles of animals were removed at months 3, 4, and 6 after distraction. Biopsy samples of distracted and contralateral side masseter muscles were histopathologically evaluated and mean area of muscle fibers (MAF) was evaluated with histomorphometric methods. Results were statistically analyzed. Mild to moderate atrophy of the fibers, and necrosis and myophagocytosis in some areas were the leading features at month 3 and which were decreased at month 4 in distracted side-muscle specimens, with no statistically significant differences when compared with non-distracted side muscles at the same periods. Almost completely, normal fibers were detected in distracted muscle specimens at month 6. Evidence of myopathic changes was found to disappear at month 6 and no significant difference was found in the MAF of distracted side muscles. This study showed that the masseter muscle could adapt to gradual lengthening of the mandible within 6 months. Regenerative features and some degree of atrophic changes that could be observed at months 3 and 4 disappeared at month 6, with adaptation of the fibers.
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    Long-term results of arthrocentesis in degenerative temporomandibular disorders
    (Mosby-Elsevier, 2009) Önder, M. Ercüment; Tüz, Hakan H.; Koçyiğit, Doruk; Kişnişçi, Reha S.
    Objectives. Long-term efficacy of arthrocentesis was investigated in patients with degenerative temporomandibular disorder (TMD) in this clinical study. Study design. Twenty-two joints of 15 patients with degenerative TMD were included as the study group, and 16 joints of 10 patients served as the control group. Arthrocentesis procedures in upper joint spaces were performed. The study group patients' mean follow-up period was 36.7 +/- 18.7 months, whereas the control group were kept for an average 9.9 +/- 2.8 months. Results were statistically compared using 1-way repeated analysis of variance and t test. Results. Pretreatment maximal interincisal opening increased significantly from 33.6 +/- 6.0 mm to 37.8 +/- 6.0 mm in the study group. Pretreatment pain and crepitus scores decreased significantly from 71.0 +/- 6.6 to 27.0 +/- 16 and 0.73 +/- 0.4 to 0.6 +/- 0.5, respectively, in the study group. Conclusions. Arthrocentesis was found to be a useful method for the treatment of degenerative TMDs, and the outcomes of treatment provide long-term cure for degenerative temporomandibular joints. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: e1-e5)